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Akademický článek

Genome-wide methylation profiling identified novel differentially hypermethylated biomarker MPPED2 in colorectal cancer

Autor: Simeng Gu, Shujuan Lin, Ding Ye, Sangni Qian, Danjie Jiang, Xiaocong Zhang, Qilong Li, Jinhua Yang, Xiaojiang Ying, Zhenjun Li, Mengling Tang, Jianbing Wang, Mingjuan Jin, Kun Chen

Publikováno v: Clinical Epigenetics, Vol 11, Iss 1, Pp 1-12 (2019)

Abstract Background Epigenetic alternation is a common contributing factor to neoplastic transformation. Although previous studies have reported a cluster of aberrant promoter methylation changes associated with silencing of tumor suppressor genes, l

Externí odkaz: https://doaj.org/article/e1b6e24454be4847ad2dbd248933695a

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Akademický článek

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MPPED2 is downregulated in glioblastoma, and its restoration inhibits proliferation and increases the sensitivity to temozolomide of glioblastoma cells

Autor: Pierlorenzo Pallante, Marco De Martino, Cristina Quintavalle, Alfredo Fusco, Simona Pellecchia, Francesco Esposito

Publikováno v: Cell Cycle

Glioblastoma (GBM) is the most aggressive and lethal neoplasia of the central nervous system in adults. Based on the molecular signature genes, GBM has been classified in proneural, neural, mesenchymal and classical subtypes. The Metallophosphoestera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0271066f17a98db86740bdd10dbbf2d4
https://europepmc.org/articles/PMC8078659/

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The Metallophosphoesterase-Domain-Containing Protein 2 (MPPED2) Gene Acts as Tumor Suppressor in Breast Cancer

Autor: Lorenzo Chiariotti, Simona Pellecchia, Romina Sepe, Mariana Severo Ramundo, Elvira Crescenzi, Pasquale Pisapia, Pierlorenzo Pallante, Gabriella De Vita, Claudio Bellevicine, Mariella Cuomo, Luigi Terracciano, Alfredo Fusco, Antonella Federico, Sara Carmela Credendino, Pedro Nicolau-Neto

Publikováno v: Cancers, Vol 11, Iss 6, p 797 (2019)
Cancers (Basel) 11 (2019). doi:10.3390/cancers11060797
info:cnr-pdr/source/autori:Pellecchia S.; Sepe R.; Federico A.; Cuomo M.; Credendino S.C.; Pisapia P.; Bellevicine C.; Nicolau-Neto P.; Ramundo M.S.; Crescenzi E.; de Vita G.; Terracciano L.M.; Chiariotti L.; Fusco A.; Pallante P./titolo:The metallophosphoesterase-domain-containing protein 2 (MPPED2) gene acts as tumor suppressor in breast cancer/doi:10.3390%2Fcancers11060797/rivista:Cancers (Basel)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
Cancers
Volume 11
Issue 6

Background: We have recently reported the downregulation of the Metallophosphoesterase-domain-containing protein 2 (MPPED2) gene and its cognate long non-coding RNA, MPPED2-AS1, in papillary thyroid carcinomas. Functional studies supported a tumor su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf212088a31f8a4bff307e712bfeb644
https://www.mdpi.com/2072-6694/11/6/797

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The

Autor: Simona, Pellecchia, Romina, Sepe, Antonella, Federico, Mariella, Cuomo, Sara Carmela, Credendino, Pasquale, Pisapia, Claudio, Bellevicine, Pedro, Nicolau-Neto, Mariana, Severo Ramundo, Elvira, Crescenzi, Gabriella, De Vita, Luigi Maria, Terracciano, Lorenzo, Chiariotti, Alfredo, Fusco, Pierlorenzo, Pallante

Publikováno v: Cancers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::13499380b766831d30fc9acaa398945c
https://pubmed.ncbi.nlm.nih.gov/31181813

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Akademický článek

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Dissertation/ Thesis

Biochemical and Functional Studies on the Evolutionarily Conserved MPPED1/MPPED2 Protein Family

Autor: Janardan, Vishnu

A large number of evolutionarily conserved genes have been identified by comparative genomics approaches. However, a considerable fraction of these genes lack functional characterization despite the availability of several bioinformatics approaches f

Externí odkaz: http://etd.iisc.ernet.in/2005/3545
http://etd.iisc.ernet.in/abstracts/4414/G27339-Abs.pdf

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