Zobrazeno 1 - 10
of 110
pro vyhledávání: '"MOTOSHI OUCHI"'
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Hyperuricemia often accompanies hypertension, diabetes, dyslipidemia, metabolic syndrome, and chronic renal disease; it is also closely related to cardiovascular disease. Moreover, several epidemiological studies have linked hyperuricemia and ischemi
Externí odkaz:
https://doaj.org/article/5654753c890e4f3e837384589b886916
Autor:
Motoshi Ouchi, Asuka Morita, Keitaro Satoh, Shunsuke Kobayashi, Misao Terada, Hiroe Kon, Keitaro Hayashi, Tatsuya Suzuki, Kenzo Oba, Hitoshi Sugihara, Masahiro Yasutake, Naohiko Anzai, Tomoe Fujita
Publikováno v:
Journal of Pharmacological Sciences, Vol 149, Iss 2, Pp 66-72 (2022)
Organ bath experiments are conventionally used to investigate the physiological actions and effects of hormones and drugs on organ responses. We developed an experimental method to reproduce insulin secretion from isolated rat pancreas preparations,
Externí odkaz:
https://doaj.org/article/1b2bdd34a7454a31b8619adc8ad7214a
Autor:
Masanari Kuwabara, Tomoko Fukuuchi, Yuhei Aoki, Einosuke Mizuta, Motoshi Ouchi, Masafumi Kurajoh, Tatsuya Maruhashi, Atsushi Tanaka, Nagisa Morikawa, Kensuke Nishimiya, Naoyuki Akashi, Yoshihiro Tanaka, Naoyuki Otani, Mihoko Morita, Hiroshi Miyata, Tappei Takada, Hiroshi Tsutani, Kazuhide Ogino, Kimiyoshi Ichida, Ichiro Hisatome, Kohtaro Abe
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1519 (2023)
The prevalence of patients with hyperuricemia or gout is increasing worldwide. Hyperuricemia and gout are primarily attributed to genetic factors, along with lifestyle factors like consuming a purine-rich diet, alcohol and/or fructose intake, and phy
Externí odkaz:
https://doaj.org/article/f8bcd732d1774a70b7cf7e3d0a39b2e1
Autor:
Ikuko Shibasaki, Motoshi Ouchi, Taira Fukuda, Go Tsuchiya, Hironaga Ogawa, Yusuke Takei, Masahiro Tezuka, Yuta Kanazawa, Satoshi Katayanagi, Naohiro Nozawa, Takashi Mizushima, Shigeru Toyoda, Hirotsugu Fukuda, Toshiaki Nakajima
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 39, Iss , Pp 101003- (2022)
Background: Cardiovascular surgery in older patients with sarcopenia has high rates of major complications, long hospital stays, readmissions, and discharge transfers. However, the factors that influence the length of hospital stay are unknown. This
Externí odkaz:
https://doaj.org/article/336847a01a6c4aaab1e5b1b91f22bb65
Autor:
Naoyuki Otani, Motoshi Ouchi, Einosuke Mizuta, Asuka Morita, Tomoe Fujita, Naohiko Anzai, Ichiro Hisatome
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1255 (2023)
The importance of uric acid, the final metabolite of purines excreted by the kidneys and intestines, was not previously recognized, except for its role in forming crystals in the joints and causing gout. However, recent evidence implies that uric aci
Externí odkaz:
https://doaj.org/article/a3784758ba6e481184245e7b58f99eb6
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 652 (2022)
Hypouricemia is recognized as a rare disorder, defined as a serum uric acid level of 2.0 mg/dL or less. Hypouricemia is divided into an overexcretion type and an underproduction type. The former typical disease is xanthinuria, and the latter is renal
Externí odkaz:
https://doaj.org/article/4d9c3ab2b92440e9a2e2371d3884526f
Autor:
Takayuki Hori, Motoshi Ouchi, Naoyuki Otani, Masakatsu Nohara, Asuka Morita, Yusuke Otsuka, Promsuk Jutabha, Ikuko Shibasaki, Yasushi Matsushita, Tomoe Fujita, Hirotsugu Fukuda, Naohiko Anzai
Publikováno v:
Journal of Pharmacological Sciences, Vol 136, Iss 4, Pp 196-202 (2018)
The purpose of this study was to create novel urate under-excretion animal models using pyrazinamide and to evaluate whether dihydropyridine calcium channel blockers (CCBs) have uricosuric effects in vivo.Adult male ICR mice were treated with pyrazin
Externí odkaz:
https://doaj.org/article/f2f6897de944435983abc6f100a1dc66
Autor:
Keitaro Hayashi, Promsuk Jutabha, Sumiko Maeda, Yothaisong Supak, Motoshi Ouchi, Hitoshi Endou, Tomoe Fujita, Masayuki Chida, Naohiko Anzai
Publikováno v:
Journal of Pharmacological Sciences, Vol 132, Iss 3, Pp 201-204 (2016)
L-type amino acid transporter 1 (LAT1, SLC7A5) incorporates essential amino acids into cells. Recent studies have shown that LAT1 is a predominant transporter in various human cancers. However, the function of LAT1 in thymic carcinoma remains unknown
Externí odkaz:
https://doaj.org/article/6058706be7b249baabd7f8730bb9aec4
Autor:
Ikuko Shibasaki, Naoyuki Otani, Shunsuke Saito, Hironaga Ogawa, Taito Masawa, Go Tsuchiya, Yusuke Takei, Masahiro Tezuka, Yuta Kanazawa, Yasuyuki Kanno, Shohei Yokoyama, Shotaro Hirota, Ken Niitsuma, Taiki Matsuoka, Taisuke Konishi, Kouji Ogata, Motoshi Ouchi, Shigeru Toyoda, Hirotsugu Fukuda
Publikováno v:
Journal of cardiology.
Post-myocardial infarction ventricular septal rupture (PIVSR) is becoming increasingly rare in the percutaneous coronary intervention era; however, the mortality rates remain high. Surgical repair is the gold standard treatment for PIVSR but is assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8816cbf1780fad8f079769dbea25d91a
https://pubmed.ncbi.nlm.nih.gov/36503063
https://pubmed.ncbi.nlm.nih.gov/36503063
Autor:
Yoshifumi Kurosaki, Rikke Nielsen, Motoshi Ouchi, Asuka Morita, Akemi Imoto, Fumitaka Kawakami, Yoshiko Iizuka, Geraldine Mollet, Takafumi Ichikawa, Masanori Yokoba, Masato Katagiri, Tsuneo Takenaka, Naohito Ishii
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Proteinuria is a major risk factor for the progression of chronic kidney disease. Protein overload in the proximal tubular epithelial cells causes oxidative stress, lysosomal dysfunction, inflammation and apoptosis, resulting in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b7caaf3cffaffb7dbcd09d374b3bd62
https://doi.org/10.1093/ndt/gfac070.069
https://doi.org/10.1093/ndt/gfac070.069