Zobrazeno 1 - 10
of 24
pro vyhledávání: '"MOLLY CRAXTON"'
Autor:
Melissa Huang, Jennifer Macdonald, Isabelle Lavenir, Renren Chen, Molly Craxton, Elizabeth Slavik-Smith, Stephen W. Davies, Michel Goedert
Publikováno v:
eneuro. 9:ENEURO.0247-22.2022
Alzheimer’s Disease (AD) is characterized by the pathologic assembly of amyloid β (Aβ) peptide, which deposits into extracellular plaques, and tau, which accumulates in intraneuronal inclusions. To investigate the link between Aβ and tau patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd137a2b59a43d518afcfa5639a64c34
https://doi.org/10.1523/eneuro.0247-22.2022
https://doi.org/10.1523/eneuro.0247-22.2022
Autor:
R. Bryan Sutton, Abujiang Pataer, Kerry L. Fuson, Molly Craxton, Sunil Chada, Mingzhong Zheng, Rajagopal Ramesh
Publikováno v:
Journal of Biological Chemistry. 284:30526-30533
Human interleukin-24 (IL-24) is unique among the IL-10 superfamily as there is considerable evidence that it possesses multiple anti-cancer properties, including direct tumor cell cytotoxicity, helper T cell (TH1) immune stimulation, and anti-angioge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5ef9cd439cab074e43793892635c559
https://doi.org/10.1074/jbc.m109.036061
https://doi.org/10.1074/jbc.m109.036061
Autor:
Molly Craxton, Michel Goedert
Publikováno v:
FEBS Letters. 460:417-422
The synaptotagmin gene family currently includes 12 members. Analysis of the three known genomic synaptotagmin sequences reveals conserved exon-intron patterns which delineate the synaptotagmin structural domains. We used expressed sequence tag, reve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699ec4ff469c0de67b0138fee396a41c
https://doi.org/10.1016/s0014-5793(99)01382-4
https://doi.org/10.1016/s0014-5793(99)01382-4
Publikováno v:
FEBS Letters. 383:273-276
Stress-activated protein kinases are MAP kinase homologues that are activated by cellular stresses, bacterial endotoxin and inflammatory cytokines. They are activated by a dual threonine/tyrosine phosphorylation within a TPY sequence in the case of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ab58a2ea205851f7f724047940330f
https://doi.org/10.1016/0014-5793(96)00255-4
https://doi.org/10.1016/0014-5793(96)00255-4
Autor:
Michel Goedert, Molly Craxton
Publikováno v:
FEBS Letters. 361:196-200
Regulated Ca2+-dependent release of transmitters from synaptic vesicles is an important characteristic of chemical neurotransmission. Synaptotagmins are abundant synaptic vesicle transmembrane proteins that probably function as Ca2+ sensors. Molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02e559c7843e8753bff948c35a437ca
https://doi.org/10.1016/0014-5793(95)00176-a
https://doi.org/10.1016/0014-5793(95)00176-a
Autor:
Molly Craxton
Publikováno v:
BMC Genomics, Vol 11, Iss 1, p 37 (2010)
BMC Genomics
BMC Genomics
Background Synaptotagmin proteins were first identified in nervous tissue, residing in synaptic vesicles. Synaptotagmins were subsequently found to form a large family, some members of which play important roles in calcium triggered exocytic events.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ed400f5deb975c176a27f5395c2ecb
http://www.biomedcentral.com/1471-2164/11/37
http://www.biomedcentral.com/1471-2164/11/37
Autor:
Molly Craxton
Publikováno v:
Methods. 3:20-26
Linear amplification sequencing is a simple, general-purpose sequencing method using Taq polymerase in cycled rounds of primer extension in the presence of deoxynucleotides and dideoxynucleotides. The method can use DNA templates produced from a wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de86c7539335984cbe4482afa279577e
https://doi.org/10.1016/s1046-2023(05)80159-8
https://doi.org/10.1016/s1046-2023(05)80159-8
Autor:
Molly Craxton
Publikováno v:
BMC Genomics, Vol 5, Iss 1, p 43 (2004)
BMC Genomics
BMC Genomics
Background Synaptotagmins exist as a large gene family in mammals. There is much interest in the function of certain family members which act crucially in the regulated synaptic vesicle exocytosis required for efficient neurotransmission. Knowledge o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3719603776bc981dee4d08b6aafd30bb
https://doi.org/10.1186/1471-2164-5-43
https://doi.org/10.1186/1471-2164-5-43
Publikováno v:
Gene. 341
Filamentous tau deposits are a defining feature of a number of human neurodegenerative diseases. Apes and monkeys have been reported to be differentially susceptible to developing tau pathology. Despite this, only little is known about the organisati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803b3bd580d116f975827ce3c824a2a5
https://pubmed.ncbi.nlm.nih.gov/15474313
https://pubmed.ncbi.nlm.nih.gov/15474313
Intracellular membrane traffic is governed by a conserved set of proteins, including Syts (synaptotagmins). The mammalian Syt family includes 15 isoforms. Syts are membrane proteins that possess tandem C2 domains (C2AB) implicated in calcium-dependen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0818e07b47265c80a5fb82c88096523
https://europepmc.org/articles/PMC1223993/
https://europepmc.org/articles/PMC1223993/
