Zobrazeno 1 - 10 of 252 pro vyhledávání: '"MN, Weedon"'
1
Influence of family history on penetrance of hereditary cancers in a population setting
Autor: L Jackson, MN Weedon, JW Harrison, AR Wood, KS Ruth, J Tyrrell, CF Wright
BackgroundWe sought to investigate how penetrance of familial cancer syndromes varies with family history using a population-based cohort.MethodsWe analysed 454,712 UK Biobank participants with exome sequence and clinical data. We identified particip
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a5942e3479cbb3e09bb4bb2f1e138256
https://doi.org/10.1101/2022.07.08.22277415
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3
Periodical
Use of SNP chips to detect rare pathogenic variants: retrospective, population based diagnostic evaluation
Autor: MN, Weedon, L, Jackson, JW, Harrison, KS, Ruth, J, Tyrrell, AT, Hattersley, CF, Wright
Publikováno v: BMJ (British Medical Journal); 2021, Vol. 372 Issue: 2 pn214-n214, 1p
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5
Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution
Autor: Cm, Lindgren, Im, Heid, Jc, Randall, Lamina C, Steinthorsdottir V, Qi L, Ek, Speliotes, Thorleifsson G, Cj, Willer, Bm, Herrera, Au, Jackson, Lim N, Scheet P, Soranzo N, Amin N, Ys, Aulchenko, Jc, Chambers, Drong A, Luan J, Hn, Lyon, Rivadeneira F, Sanna S, Nj, Timpson, Mc, Zillikens, Jh, Zhao, Almgren P, Bandinelli S, Aj, Bennett, Rn, Bergman, Ll, Bonnycastle, Sj, Bumpstead, Sj, Chanock, Cherkas L, Chines P, Coin L, Cooper C, Crawford G, Doering A, Dominiczak A, Asf, Doney, Ebrahim S, Elliott P, Erdos MR, Estrada K, Ferrucci L, Fischer G, Ng, Forouhi, Gieger C, Grallert H, Cj, Groves, Grundy S, Guiducci C, Hadley D, Hamsten A, As, Havulinna, Hofman A, Holle R, Jw, Holloway, Illig T, Isomaa B, Lc, Jacobs, Jameson K, Jousilahti P, Karpe F, Kuusisto J, Laitinen J, Gm, Lathrop, Da, Lawlor, Mangino M, Wl, Mcardle, Meitinger T, Ma, Morken, Ap, Morris, Munroe P, Narisu N, Nordström A, Nordström P, Ba, Oostra, Cna, Palmer, Payne F, Jf, Peden, Inga Prokopenko, Renström F, Ruokonen A, Salomaa V, Ms, Sandhu, Lj, Scott, Scuteri A, Silander K, Song K, Yuan X, Hm, Stringham, Aj, Swift, Tuomi T, Uda M, Vollenweider P, Waeber G, Wallace C, Gb, Walters, Mn, Weedon, Jcm, Witteman, Zhang C, Zhang W, Mj, Caulfield, Fs, Collins, Davey Smith G, Inm, Day, Pw, Franks, At, Hattersley, Fb, Hu, Jarvelin M, Kong A, Js, Kooner, Laakso M, Lakatta E, Mooser V, Ad, Morris, Peltonen L, Nj, Samani, Td, Spector, Dp, Strachan, Tanaka T, Tuomilehto J, Ag, Uitterlinden, Cm, Duijn, Nj, Wareham, Procardis, Watkins For The Consortia H., Dm, Waterworth, Boehnke M, Deloukas P, Groop L, Dj, Hunter, Thorsteinsdottir U, Schlessinger D, H-, Wichmann, Tm, Frayling, Gr, Abecasis, Jn, Hirschhorn, Rjf, Loos, Stefansson K, Kl, Mohlke, Barroso I, Giant Mi, Mccarthy For The Consortium
Publikováno v: Europe PubMed Central
PLoS Genetics
PLoS Genetics, Vol 5, Iss 7 (2009)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4aa71e313de404e331242e6d0f0e4f
http://europepmc.org/abstract/PMC/PMC2722420
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6
Akademický článek
Type 1 diabetes genetic risk score variation across ancestries using whole genome sequencing and array-based approaches.
Autor: Arni AM; Department of Clinical and Biomedical Sciences, RILD Building, Royal Devon and Exeter Hospital, University of Exeter, Barrack Road, Exeter, EX2 5DW, UK., Fraser DP; Department of Clinical and Biomedical Sciences, RILD Building, Royal Devon and Exeter Hospital, University of Exeter, Barrack Road, Exeter, EX2 5DW, UK., Sharp SA; Department of Pediatrics, Stanford University, Stanford, CA, 94305, USA., Oram RA; Department of Clinical and Biomedical Sciences, RILD Building, Royal Devon and Exeter Hospital, University of Exeter, Barrack Road, Exeter, EX2 5DW, UK., Johnson MB; Department of Clinical and Biomedical Sciences, RILD Building, Royal Devon and Exeter Hospital, University of Exeter, Barrack Road, Exeter, EX2 5DW, UK., Weedon MN; Department of Clinical and Biomedical Sciences, RILD Building, Royal Devon and Exeter Hospital, University of Exeter, Barrack Road, Exeter, EX2 5DW, UK., Patel KA; Department of Clinical and Biomedical Sciences, RILD Building, Royal Devon and Exeter Hospital, University of Exeter, Barrack Road, Exeter, EX2 5DW, UK. K.A.Patel@exeter.ac.uk.
Publikováno v: Scientific reports [Sci Rep] 2024 Dec 28; Vol. 14 (1), pp. 31044. Date of Electronic Publication: 2024 Dec 28.
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7
Editorial & Opinion
Accurate and cost-effective generation of a genetic risk score direct from blood lysates.
Autor: Locke JM; Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Level 3, RILD Building, Barrack Road, Exeter, EX2 5DW, UK. j.locke@exeter.ac.uk., Spurrier B; Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Level 3, RILD Building, Barrack Road, Exeter, EX2 5DW, UK., Laver TW; Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Level 3, RILD Building, Barrack Road, Exeter, EX2 5DW, UK., Houghton JAL; Exeter Genomics Laboratory, Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK., Colclough K; Exeter Genomics Laboratory, Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK., Weedon MN; Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Level 3, RILD Building, Barrack Road, Exeter, EX2 5DW, UK., Oram RA; Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Level 3, RILD Building, Barrack Road, Exeter, EX2 5DW, UK.
Publikováno v: Journal of translational medicine [J Transl Med] 2024 Dec 20; Vol. 22 (1), pp. 1128. Date of Electronic Publication: 2024 Dec 20.
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8
Akademický článek
Type 2 diabetes pathway-specific polygenic risk scores elucidate heterogeneity in clinical presentation, disease progression and diabetic complications in 18,217 Chinese individuals with type 2 diabetes.
Autor: Yu G; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; CUHK-SJTU Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Tam CHT; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; CUHK-SJTU Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Lim CKP; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; CUHK-SJTU Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Shi M; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; CUHK-SJTU Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Lau ESH; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Ozaki R; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China., Lee HM; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; CUHK-SJTU Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Ng ACW; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; CUHK-SJTU Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Hou Y; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; CUHK-SJTU Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Fan B; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; CUHK-SJTU Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Huang C; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; CUHK-SJTU Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Wu H; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Yang A; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Cheung HM; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Lee KF; Department of Medicine and Geriatrics, Kwong Wah Hospital, Hong Kong, China., Siu SC; Diabetes Centre, Tung Wah Eastern Hospital, Hong Kong, China., Hui G; Diabetes Centre, Tung Wah Eastern Hospital, Hong Kong, China., Tsang CC; Diabetes and Education Centre, Alice Ho Miu Ling Nethersole Hospital, Hong Kong, China., Lau KP; North District Hospital, Hong Kong, China., Leung JYY; Department of Medicine and Geriatrics, Ruttonjee Hospital, Hong Kong, China., Cheung EYN; Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong, China., Tsang MW; Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong, China., Kam G; Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong, China., Lau IT; Tseung Kwan O Hospital, Hong Kong, China., Li JKY; Department of Medicine, Yan Chai Hospital, Hong Kong, China., Yeung VTF; Centre for Diabetes Education and Management, Our Lady of Maryknoll Hospital, Hong Kong, China., Lau E; Department of Medicine, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China., Lo S; Department of Medicine, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China., Fung S; Department of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong, China., Cheng YL; Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Hong Kong, China., Szeto CC; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Chow E; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Kong APS; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Tam WH; Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong, China.; CUHK Medical Centre, Hong Kong, China., Luk AOY; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; CUHK-SJTU Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Weedon MN; University of Exeter Medical School, Exeter, UK., So WY; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; CUHK-SJTU Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Chan JCN; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China.; CUHK-SJTU Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China., Oram RA; University of Exeter Medical School, Exeter, UK., Ma RCW; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China. rcwma@cuhk.edu.hk.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China. rcwma@cuhk.edu.hk.; CUHK-SJTU Joint Research Centre in Diabetes Genomics and Precision Medicine, The Chinese University of Hong Kong, Hong Kong, China. rcwma@cuhk.edu.hk.; Laboratory for Molecular Epidemiology in Diabetes, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China. rcwma@cuhk.edu.hk.; Diabetes Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China. rcwma@cuhk.edu.hk.
Publikováno v: Diabetologia [Diabetologia] 2024 Nov 12. Date of Electronic Publication: 2024 Nov 12.
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9
Akademický článek
Type 1 diabetes genetic risk contributes to phenotypic presentation in monogenic autoimmune diabetes.
Autor: Luckett AM; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK, University of Exeter Medical School, Exeter, UK., Hawkes G; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK, University of Exeter Medical School, Exeter, UK., Green HD; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK, University of Exeter Medical School, Exeter, UK., De Franco E; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK, University of Exeter Medical School, Exeter, UK., Hagopian WA; Indiana University School of Medicine, Department of Pediatrics, Indianapolis, USA., Roep BO; Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands., Weedon MN; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK, University of Exeter Medical School, Exeter, UK., Oram RA; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK, University of Exeter Medical School, Exeter, UK.; Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK., Johnson MB; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK, University of Exeter Medical School, Exeter, UK.
Publikováno v: Diabetes [Diabetes] 2024 Nov 12. Date of Electronic Publication: 2024 Nov 12.
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10
Akademický článek
A homozygous TARS2 variant is a novel cause of syndromic neonatal diabetes.
Autor: Donis R; Department of Clinical and Biomedical Science, University of Exeter Faculty of Health and Life Sciences, Exeter, UK., Patel KA; Department of Clinical and Biomedical Science, University of Exeter Faculty of Health and Life Sciences, Exeter, UK., Wakeling MN; Department of Clinical and Biomedical Science, University of Exeter Faculty of Health and Life Sciences, Exeter, UK., Johnson MB; Department of Clinical and Biomedical Science, University of Exeter Faculty of Health and Life Sciences, Exeter, UK., Amoli MM; Metabolic Disorders Research Centre, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran., Yildiz M; Department of Paediatric Endocrinology, İstanbul University, İstanbul Faculty of Medicine, İstanbul, Turkey., Akçay T; Department of Paediatric Endocrinology, Bakırköy Dr. Sadi Konuk Education and Research Hospital, İstanbul, Turkey., Aspi I; Nanavati Super Speciality Hospital, Mumbai, India.; Juvenile Diabetes Foundation, Maharashtra Chapter, Mumbai, India., Yong J; Children and Young People's Diabetes Team, St James's University Hospital, Leeds, UK., Yaghootkar H; College of Health and Science, University of Lincoln, Joseph Banks Laboratories, Lincoln, UK., Weedon MN; Department of Clinical and Biomedical Science, University of Exeter Faculty of Health and Life Sciences, Exeter, UK., Hattersley AT; Department of Clinical and Biomedical Science, University of Exeter Faculty of Health and Life Sciences, Exeter, UK., Flanagan SE; Department of Clinical and Biomedical Science, University of Exeter Faculty of Health and Life Sciences, Exeter, UK., De Franco E; Department of Clinical and Biomedical Science, University of Exeter Faculty of Health and Life Sciences, Exeter, UK.
Publikováno v: Diabetic medicine : a journal of the British Diabetic Association [Diabet Med] 2024 Nov 07, pp. e15471. Date of Electronic Publication: 2024 Nov 07.
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