Preconceptional paternal caloric restriction of high-fat diet-induced obesity in Wistar rats dysregulates the metabolism of their offspring via AMPK/SIRT1 pathway

Autor: Rachakatla Anuradha, M. Srinivas, M. Satyavani, K. Suresh, MN. Muralidhar, Kalashikam Rajender Rao

Publikováno v: Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-15 (2024)

Abstract Background Obesity is a metabolic syndrome where allelic and environmental variations together determine the susceptibility of an individual to the disease. Caloric restriction (CR) is a nutritional dietary strategy recognized to be benefici

Externí odkaz: https://doaj.org/article/7940dd45b139428a88390e5142695868

Preconceptional paternal caloric restriction of high-fat diet-induced obesity in Wistar rats dysregulates the metabolism of their offspring via AMPK/SIRT1 pathway.

Autor: Anuradha R; Animal Facility, ICMR-National Institute of Nutrition, Tarnaka, Hyderabad, 500007, Telangana, India., Srinivas M; Animal Facility, ICMR-National Institute of Nutrition, Tarnaka, Hyderabad, 500007, Telangana, India., Satyavani M; Animal Facility, ICMR-National Institute of Nutrition, Tarnaka, Hyderabad, 500007, Telangana, India., Suresh K; Animal Facility, ICMR-National Institute of Nutrition, Tarnaka, Hyderabad, 500007, Telangana, India., Muralidhar MN; ICMR-Centre for Research, Management and Control of Haemoglobinopathies (ICMR- CRMCH), Chandrapur, 442406, Maharashtra, India., Rajender Rao K; Animal Facility, ICMR-National Institute of Nutrition, Tarnaka, Hyderabad, 500007, Telangana, India. rkrajender@yahoo.com.

Publikováno v: Lipids in health and disease [Lipids Health Dis] 2024 Jun 08; Vol. 23 (1), pp. 174. Date of Electronic Publication: 2024 Jun 08.

Differential response of rat strains to obesogenic diets underlines the importance of genetic makeup of an individual towards obesity.

Autor: Mn M; Laboratory of Molecular Genetics, National Centre for Laboratory Animal Sciences, National Institute of Nutrition, Hyderabad, 500 007, Telangana, India., Smvk P; Laboratory of Molecular Genetics, National Centre for Laboratory Animal Sciences, National Institute of Nutrition, Hyderabad, 500 007, Telangana, India., Battula KK; Laboratory of Molecular Genetics, National Centre for Laboratory Animal Sciences, National Institute of Nutrition, Hyderabad, 500 007, Telangana, India., Nv G; Laboratory of Molecular Genetics, National Centre for Laboratory Animal Sciences, National Institute of Nutrition, Hyderabad, 500 007, Telangana, India., Kalashikam RR; Laboratory of Molecular Genetics, National Centre for Laboratory Animal Sciences, National Institute of Nutrition, Hyderabad, 500 007, Telangana, India. rkrajender@yahoo.com.

Publikováno v: Scientific reports [Sci Rep] 2017 Aug 22; Vol. 7 (1), pp. 9162. Date of Electronic Publication: 2017 Aug 22.