Frequent overexpression of AMAP1, an Arf6 effector in cell invasion, is characteristic of the MMTV-PyMT rather than the MMTV-Neu human breast cancer model

Autor: Yutaro Otsuka, Tsukasa Oikawa, Hinako Yoshino, Shigeru Hashimoto, Haruka Handa, Hiroki Yamamoto, Ari Hashimoto, Hisataka Sabe

Publikováno v: Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-9 (2018)

Abstract Background The small GTPase Arf6 and its downstream effector AMAP1 (also called ASAP1/DDEF1) constitute a signaling pathway promoting cell invasion, in which AMAP1 interacts with several different proteins, including PRKD2, EPB41L5, paxillin

Externí odkaz: https://doaj.org/article/c6ca8b57c90341baaf1cc101ba342cf7

Effects of aerobic exercise training on myomirs expression in cachectic and non-cachectic cancer mice

Autor: Edilamar Menezes de Oliveira, Gabriel Cardial Tobias, Patricia Chakur Brum, João Lucas Penteado Gomes, André C. Silveira, Tiago Fernandes, Roger Chammas, Carlos Eduardo Negrão

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cancers, Vol 13, Iss 5728, p 5728 (2021)
Cancers
Volume 13
Issue 22

We investigated the effects of AET on myomiRs expression in the skeletal muscle and serum of colon cachectic (CT26) and breast non-cachectic (MMTV-PyMT) cancer mice models. Colon cancer decreased microRNA-486 expression, increasing PTEN in tibialis a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1998b5914013452049b039ed570e2a5a

Single-cell analysis reveals immune modulation and metabolic switch in tumor-draining lymph nodes

Autor: Shao Chun Wang, Shih-Sheng Jiang, Yen-Liang Li, Jing-Yi Chen, You-Syuan Lai, Chung-Hsing Chen, Wen-Chun Hung

Publikováno v: OncoImmunology, Vol 9, Iss 1 (2020)
Oncoimmunology
article-version (VoR) Version of Record

Lymph-node metastasis is a prognosis factor for poor clinical outcome of breast cancer patients. Currently, how breast cancer cells establish pre-metastatic niche in the tumor-draining lymph nodes (TDLNs) is still unclear. To address this question, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97945b0fd0d09a8c815e55cb4a8dd973
https://doaj.org/article/a883f58d92e74c40ad255a97acaaf2d1

Frequent overexpression of AMAP1, an Arf6 effector in cell invasion, is characteristic of the MMTV-PyMT rather than the MMTV-Neu human breast cancer model

Autor: Hiroki Yamamoto, Yutaro Otsuka, Shigeru Hashimoto, Ari Hashimoto, Hinako Yoshino, Tsukasa Oikawa, Haruka Handa, Hisataka Sabe

Publikováno v: Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-9 (2018)

Background The small GTPase Arf6 and its downstream effector AMAP1 (also called ASAP1/DDEF1) constitute a signaling pathway promoting cell invasion, in which AMAP1 interacts with several different proteins, including PRKD2, EPB41L5, paxillin, and cor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abf868a22b0326a3afecf48985c32b9
https://doi.org/10.1186/s12964-017-0212-z

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