Zobrazeno 1 - 10
of 817
pro vyhledávání: '"MMP14"'
Autor:
Xuezhou Zhang, Baoan Hong, Hongwei Li, Jiahui Zhao, Mingchuan Li, Dechao Wei, Yongxing Wang, Ning Zhang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Basement membrane (BM) is an important component of the extracellular matrix, which plays an important role in the growth and metastasis of tumor cells. However, few biomarkers based on BM have been developed for prognostic assess
Externí odkaz:
https://doaj.org/article/51f46a545cb941d6a4c6cf2b04630229
Autor:
Jordi Gonzalez‐Molina, Paula Hahn, Raul Maia Falcão, Okan Gultekin, Georgia Kokaraki, Valentina Zanfagnin, Tirzah Braz Petta, Kaisa Lehti, Joseph W. Carlson
Publikováno v:
Molecular Oncology, Vol 18, Iss 4, Pp 850-865 (2024)
Fibrillar collagen deposition, stiffness and downstream signalling support the development of leiomyomas (LMs), common benign mesenchymal tumours of the uterus, and are associated with aggressiveness in multiple carcinomas. Compared with epithelial c
Externí odkaz:
https://doaj.org/article/ce0b7c7310a54a3d94cc48e84d821fb1
Autor:
Yanling Yin, Yu Zhang, Xiaobo Zhang, Qi Zhang, Jiachen Wang, Tian Yang, Chen Liang, Wu Li, Jie Liu, Xiaojuan Ma, Jinwei Duan, Wenzhen Shi, Ye Tian
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Background Cerebral stroke (CS) is the leading cause of death in China, and a complex disease caused by both alterable risk factors and genetic factors. This study intended to investigate the association of MMP3, MMP14, and MMP25 single nucl
Externí odkaz:
https://doaj.org/article/e8ae4a70f4224595923d2c1c8d5048f5
Autor:
Dan Peng, Juan Li, Yin Li, Lingling Bai, Anying Xiong, Xiang He, Xiaolan Li, Qin Ran, Lei Zhang, Manling Jiang, Junyi Wang, Elaine Lai-Han Leung, Pingchang Yang, Guoping Li
Publikováno v:
Pharmacological Research, Vol 200, Iss , Pp 107070- (2024)
Fibrotic hypersensitivity pneumonitis (FHP) is a fatal interstitial pulmonary disease with limited treatment options. Lung macrophages are a heterogeneous cell population that exhibit distinct subsets with divergent functions, playing pivotal roles i
Externí odkaz:
https://doaj.org/article/7768b464e5c54cda910ed841daae94fa
Autor:
Wei Li, Linyan Liu, Ming’ai Duanqing, Xiaoqing Xiong, Dejian Gan, Jin Yang, Mingya Wang, Min Zhou, Jun Yan
Publikováno v:
Autoimmunity, Vol 56, Iss 1 (2023)
AbstractAirway remodeling is an important pathologic factor in the progression of asthma. Abnormal proliferation and migration of airway smooth muscle cells (ASMCs) are important pathologic mechanisms in severe asthma. In the current study, claudin-1
Externí odkaz:
https://doaj.org/article/bfa002e261c548378b2d8ede4d8fefcd
Autor:
Ruth M. Escalona, Simon Chu, Elif Kadife, Jason K. Kelly, George Kannourakis, Jock K. Findlay, Nuzhat Ahmed
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-27 (2022)
Abstract Background The endogenous tissue inhibitor of metalloproteinase-2 (TIMP-2), through its homeostatic action on certain metalloproteinases, plays a vital role in remodelling extracellular matrix (ECM) to facilitate cancer progression. This stu
Externí odkaz:
https://doaj.org/article/bf8b668de7d74546917e2a322c13f1ee
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Olga Bugaeva, Pilvi Maliniemi, Wenche S. Prestvik, Eeva Leivo, Nicolas Kluger, Alexander Salava, Sanna Virtanen, Kirsi Jäntti, Olli Saksela, Kaisa Lehti, Paula Kujala, Kaj Krohn, Annamari Ranki
Publikováno v:
Acta Dermato-Venereologica, Vol 103 (2023)
Melanoma is a highly metastatic tumour originating from neural crest-derived melanocytes. The aim of this study was to analyse the expression of neuron navigator 3 (NAV3) in relation to membrane type-1 matrix metalloproteinase MMP14, a major regulato
Externí odkaz:
https://doaj.org/article/be93bcaba81f463c88d6229ed9d2ea83