Zobrazeno 1 - 10
of 308
pro vyhledávání: '"MMP, matrix metalloproteinase"'
Autor:
Chaofeng Yuan, Jialin Yuan, Huijie Xiao, Haitao Li, Yang Jiang, Rongnan Zhai, Jinjing Zhai, Hua Xing, Jiannan Huang
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
This study systematically and comprehensively analyzed the characteristics of matrix metalloproteinases (MMPs) in gastric cancer (GC) and revealed the relationship between MMPs and prognoses, clinicopathological features, tumor microenvironment, gene
Externí odkaz:
https://doaj.org/article/3bc7deee197742c8b3784fea4b14c993
Autor:
Kelly M. Stanton, Hongjuan Liu, Vivian Kienzle, Christina Bursill, Shisan Bao, David S. Celermajer
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundExercise is associated with a less atherogenic lipid profile; however, there is limited research on the effect of exercise on atherosclerotic plaque composition and markers of plaque stability.MethodsA total of 110 apolipoprotein (apo)E−/
Externí odkaz:
https://doaj.org/article/7a9d323b82d14e109266642074592015
Autor:
Teruki Nii, Yasuhiko Tabata
Publikováno v:
Regenerative Therapy, Vol 18, Iss, Pp 516-522 (2021)
Regenerative Therapy
Regenerative Therapy
Introduction The objective of this study is to design a co-culture system of cancer cells and three-dimensional (3D) mesenchymal stem cells (MSC) aggregates for the in vitro evaluation of cancer invasion. Methods First, the MSC of an immunosuppressiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30478d0d874b865560a7aa85190b7a7e
http://hdl.handle.net/2433/277951
http://hdl.handle.net/2433/277951
Autor:
David A. Frank, Isidora Tošić
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1167-1178 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1167-1178 (2021)
The oncogenic transcription factor signal transducer and activator of transcription 3 (STAT3) is activated constitutively in a wide array of human cancers. It is an appealing molecular target for novel therapy as it directly regulates expression of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95fc1e221705a2edcb47149735290583
http://europepmc.org/articles/PMC8569436
http://europepmc.org/articles/PMC8569436
Autor:
Sallam Hasan Abdallah, Hady Shahin, Ahmed T. El-Serafi, Cathrine Lagerwall, Ingrid Steinvall, Moustafa Elmasry, Folke Sjöberg
Publikováno v:
Regenerative Therapy
Regenerative Therapy, Vol 18, Iss, Pp 401-407 (2021)
Regenerative Therapy, Vol 18, Iss, Pp 401-407 (2021)
Introduction Regenerative solutions of the skin represent a hope for burn victims with extensive skin loss and chronic wound patients. The development of xeno-free workflow is crucial for clinical application in compliance with the directives of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ff772f667d1187525ec3c3eee467e5
http://europepmc.org/articles/PMC8531849
http://europepmc.org/articles/PMC8531849
Autor:
Masahiro Nishikawa, Ichiro Nakano, Afsana Islam, Yuji Watanabe, Daisuke Yamashita, Yasutsugu Takada, Satoshi Suehiro, Hideaki Watanabe, Junya Tanaka, Takeharu Kunieda, Yoshihiro Ohtsuka, Yutaro Sumida, Akihiro Umakoshi, Erika Hayase, Yusuke Nishi, Shota Ohsumi, Eika Usa, Saya Ozaki, Akihiro Inoue, Jun Kuwabara, Hajime Yano, Mohammed E. Choudhury
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 8, Pp 754-765 (2021)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Highlights • CLIC2 is highly expressed in benign, less invasive and less metastatic tumors. • Forced expression of CLIC2 prevents metastasis and invasion in animal tumor models. • CLIC2 is associated with decreased vascular permeability in tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a1857fc7fdf8e1121e51752c54bf4f
http://www.sciencedirect.com/science/article/pii/S1476558621000439
http://www.sciencedirect.com/science/article/pii/S1476558621000439
Autor:
Tamas Kovacs, Nandor Nagy, Ryo Hotta, Ildikó Bódi, Zoltán Varga, Allan M. Goldstein, Viktória E. Tóth, Rhian Stavely, David Dora, Szilamér Ferenczi, Krisztina J. Kovács
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1617-1641 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1617-1641 (2021)
Background & Aims Neuroinflammation in the gut is associated with many gastrointestinal (GI) diseases, including inflammatory bowel disease. In the brain, neuroinflammatory conditions are associated with blood-brain barrier (BBB) disruption and subse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a0ac8fd2f5ff2f3874cc3cf2cf105d
http://europepmc.org/articles/PMC8551790
http://europepmc.org/articles/PMC8551790
Publikováno v:
Journal of Advanced Research
Journal of Advanced Research, Vol 35, Iss, Pp 245-257 (2022)
Journal of Advanced Research, Vol 35, Iss, Pp 245-257 (2022)
Graphical abstract
Highlights • Aberrant STAT3 activation can promote neoplastic transformation by affecting cellular proliferation, invasion, metastasis, angiogenesis, and anti-apoptosis induction. • Fangchinoline abrogated protein expressi
Highlights • Aberrant STAT3 activation can promote neoplastic transformation by affecting cellular proliferation, invasion, metastasis, angiogenesis, and anti-apoptosis induction. • Fangchinoline abrogated protein expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827fdb8a08fdd8e28ed3bcdc4a40ef6f
http://europepmc.org/articles/PMC8721253
http://europepmc.org/articles/PMC8721253
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 322-339 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Fibrosis is a pathological reparative process that can occur in most organs and is responsible for nearly half of deaths in the developed world. Despite considerable research, few therapies have proven effective and been approved clinically for treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31e277e49b3a3364e9726d531259ad4
https://doi.org/10.1016/j.apsb.2020.09.001
https://doi.org/10.1016/j.apsb.2020.09.001
Autor:
Elizabeth Liu, Jennifer E. Ho, Javier Díez, Begoña López, Emily S. Lau, Amy Sarma, Thomas J. Wang, Samantha M. Paniagua, Giovanna A. Zampierollo
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • Gal-3 is a beta-galactoside–binding lectin that regulates inflammation and fibrosis and is highly predictive of heart failure events and mortality. • In a randomized placebo-controlled trial of MCP, Gal-3 inhib
Highlights • Gal-3 is a beta-galactoside–binding lectin that regulates inflammation and fibrosis and is highly predictive of heart failure events and mortality. • In a randomized placebo-controlled trial of MCP, Gal-3 inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d751a3dfc1f77fc0cd729f2b0572e2e
http://europepmc.org/articles/PMC7838053
http://europepmc.org/articles/PMC7838053