Lack of Mucosal Cholinergic Innervation Is Associated With Increased Risk of Enterocolitis in Hirschsprung's Disease

Autor: Simone Keck, Virginie Galati-Fournier, Urs Kym, Michèle Moesch, Jakob Usemann, Isabelle Müller, Ulrike Subotic, Sasha J. Tharakan, Thomas Krebs, Eleuthere Stathopoulos, Peter Schmittenbecher, Dietmar Cholewa, Philipp Romero, Bertram Reingruber, Elisabeth Bruder, NIG Study Group, Stefan Holland-Cunz

Publikováno v: Keck, Simone; Galati-Fournier, Virginie; Kym, Urs; Moesch, Michèle; Usemann, Jakob; Müller, Isabelle; Subotic, Ulrike; Tharakan, Sasha J.; Krebs, Thomas; Stathopoulos, Eleuthere; Schmittenbecher, Peter; Cholewa, Dietmar; Romero, Philipp; Reingruber, Bertram; Bruder, Elisabeth; NIG, Study Group; Holland-Cunz, Stefan (2021). Lack of Mucosal Cholinergic Innervation Is Associated With Increased Risk of Enterocolitis in Hirschsprung’s Disease. Cellular and molecular gastroenterology and hepatology, 12(2), pp. 507-545. Elsevier 10.1016/j.jcmgh.2021.03.004
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 507-545 (2021)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Hirschsprung’s disease (HSCR) is a congenital intestinal motility disorder defined by the absence of enteric neuronal cells (ganglia) in the distal gut. The development of HSCR-associated enterocolitis remains a life-threatening c

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https://doi.org/10.5167/uzh-216782