TREM1 regulates antifungal immune responses in invasive pulmonary aspergillosis

Autor: L Bernal-Martínez, SM Gonçalves, B de Andres, C Cunha, I Gonzalez Jimenez, K Lagrou, E Mellado, ML Gaspar, JA Maertens, A Carvalho, L Alcazar-Fuoli

Publikováno v: Virulence, Vol 12, Iss 1, Pp 570-583 (2021)

Pattern recognition receptors (PRRs) are responsible for Aspergillus fumigatus recognition by innate immunity and its subsequent immune signaling. The triggering receptor expressed on myeloid cells 1 (TREM1) is a recently characterized pro-inflammato

Externí odkaz: https://doaj.org/article/4d1d6092559d4913990ac809ed9d0c4b

Correction: Tyrosine kinase 2 modulates splenic B cells through type I IFN and TLR7 signaling.

Autor: Bodega-Mayor I; Molecular Biology Unit, Hospital Universitario de La Princesa and Research Institute (IIS-Princesa), Madrid, Spain.; Immunobiology Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain., Delgado-Wicke P; Molecular Biology Unit, Hospital Universitario de La Princesa and Research Institute (IIS-Princesa), Madrid, Spain., Arrabal A; Molecular Biology Unit, Hospital Universitario de La Princesa and Research Institute (IIS-Princesa), Madrid, Spain.; Immunobiology Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain., Alegría-Carrasco E; Molecular Biology Unit, Hospital Universitario de La Princesa and Research Institute (IIS-Princesa), Madrid, Spain., Nicolao-Gómez A; Molecular Biology Unit, Hospital Universitario de La Princesa and Research Institute (IIS-Princesa), Madrid, Spain., Jaén-Castaño M; Molecular Biology Unit, Hospital Universitario de La Princesa and Research Institute (IIS-Princesa), Madrid, Spain., Espadas C; Genomics Unit, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain., Dopazo A; Genomics Unit, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.; CIBER de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain., Martín-Gayo E; Genomics Unit, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.; Immunology Department, Hospital Universitario de La Princesa and IIS-Princesa, Madrid, Spain.; Faculty of Medicine, Universidad Autónoma de Madrid, Madrid, Spain., Gaspar ML; Immunobiology Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain., de Andrés B; Immunobiology Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain., Fernández-Ruiz E; Molecular Biology Unit, Hospital Universitario de La Princesa and Research Institute (IIS-Princesa), Madrid, Spain. efruiz@salud.madrid.org.; Faculty of Medicine, Universidad Autónoma de Madrid, Madrid, Spain. efruiz@salud.madrid.org.

Publikováno v: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 Nov 15; Vol. 81 (1), pp. 455. Date of Electronic Publication: 2024 Nov 15.

Immune stress suppresses innate immune signaling in preleukemic precursor B-cells to provoke leukemia in predisposed mice.

Autor: Isidro-Hernández M; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC-USAL, Campus M. de Unamuno s/n, Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Casado-García A; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC-USAL, Campus M. de Unamuno s/n, Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Oak N; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA., Alemán-Arteaga S; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC-USAL, Campus M. de Unamuno s/n, Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Ruiz-Corzo B; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC-USAL, Campus M. de Unamuno s/n, Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain., Martínez-Cano J; Immune system development and function Unit, Centro de Biología Molecular Severo Ochoa (Consejo Superior de Investigaciones Científicas -Universidad Autónoma de Madrid), Madrid, Spain., Mayado A; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Servicio de Citometría, Departamento de Medicina, Biomedical Research Networking Centre on Cancer CIBER-CIBERONC (CB16/12/00400), Institute of Health Carlos III, and Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain., Sánchez EG; Department of Pediatric Hematology and Oncology, Hospital Infantil Universitario Niño Jesús, Universidad Autónoma de Madrid, Madrid, Spain., Blanco O; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Anatomía Patológica, Universidad de Salamanca, Salamanca, Spain., Gaspar ML; Immunobiology Department, Carlos III Health Institute, 28220, Majadahonda (Madrid), Spain., Orfao A; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Servicio de Citometría, Departamento de Medicina, Biomedical Research Networking Centre on Cancer CIBER-CIBERONC (CB16/12/00400), Institute of Health Carlos III, and Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Salamanca, Spain., Alonso-López D; Bioinformatics Unit, Cancer Research Center (CSIC-USAL), Salamanca, Spain., De Las Rivas J; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Bioinformatics and Functional Genomics Research Group, Cancer Research Center (CSIC-USAL), Salamanca, Spain., Riesco S; Department of Pediatrics, Hospital Universitario de Salamanca, Paseo de San Vicente, 58-182, Salamanca, 37007, Spain., Prieto-Matos P; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Department of Pediatrics, Hospital Universitario de Salamanca, Paseo de San Vicente, 58-182, Salamanca, 37007, Spain., González-Murillo Á; Department of Pediatric Hematology and Oncology, Hospital Infantil Universitario Niño Jesús, Universidad Autónoma de Madrid, Madrid, Spain., Criado FJG; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Cirugía, , Universidad de Salamanca, Salamanca, Spain., Cenador MBG; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.; Departamento de Cirugía, , Universidad de Salamanca, Salamanca, Spain., Ramírez-Orellana M; Department of Pediatric Hematology and Oncology, Hospital Infantil Universitario Niño Jesús, Universidad Autónoma de Madrid, Madrid, Spain., de Andrés B; Immunobiology Department, Carlos III Health Institute, 28220, Majadahonda (Madrid), Spain., Vicente-Dueñas C; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain. cvd@usal.es.; Department of Pediatrics, Hospital Universitario de Salamanca, Paseo de San Vicente, 58-182, Salamanca, 37007, Spain. cvd@usal.es., Cobaleda C; Immune system development and function Unit, Centro de Biología Molecular Severo Ochoa (Consejo Superior de Investigaciones Científicas -Universidad Autónoma de Madrid), Madrid, Spain. cesar.cobaleda@csic.es., Nichols KE; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA. Kim.Nichols@STJUDE.ORG., Sánchez-García I; Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC-USAL, Campus M. de Unamuno s/n, Salamanca, Spain. isg@usal.es.; Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain. isg@usal.es.

Publikováno v: Nature communications [Nat Commun] 2023 Aug 24; Vol. 14 (1), pp. 5159. Date of Electronic Publication: 2023 Aug 24.

Age-dependent nasal immune responses in non-hospitalized bronchiolitis children.

Autor: Cortegano I; Immunobiology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain., Rodríguez M; Immunobiology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain., Hernángómez S; Pediatrics Department, Hospital El Tajo, Aranjuez, Madrid, Spain., Arrabal A; Immunobiology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain., Garcia-Vao C; Pediatrics Department, Hospital El Tajo, Aranjuez, Madrid, Spain., Rodríguez J; Pediatrics Department, Atención Primaria Galapagar, Madrid, Spain., Fernández S; Pediatrics Department, Atención Primaria Galapagar, Madrid, Spain., Díaz J; Pediatrics Department, Atención Primaria Galapagar, Madrid, Spain., de la Rosa B; Pediatrics Department, Hospital Puerta de Hierro, Madrid, Spain., Solís B; Pediatrics Department, Hospital Puerta de Hierro, Madrid, Spain., Arribas C; Pediatrics Department, Clínica Universitaria de Navarra, Madrid, Spain., Garrido F; Pediatrics Department, Clínica Universitaria de Navarra, Madrid, Spain., Zaballos A; Genomics Central Core, Instituto de Salud Carlos III (ISCIII), Madrid, Spain., Roa S; Biochemistry and Genetics Department, Universidad de Navarra, Pamplona, Spain., López V; Chronic Disease Programme Unidad de Investigación de Enfermedades Crónicas (UFIEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain., Gaspar ML; Immunobiology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain., de Andrés B; Immunobiology Department, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 Dec 06; Vol. 13, pp. 1011607. Date of Electronic Publication: 2022 Dec 06 (Print Publication: 2022).

Phosphatidic acid species 34:1 mediates expression of the myo-inositol 3-phosphate synthase gene INO1 for lipid synthesis in yeast.

Autor: Gaspar ML; Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, USA. Electronic address: mlg32@cornell.edu., Aregullin MA; Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, USA., Chang YF; Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, USA., Jesch SA; Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, USA., Henry SA; Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, USA.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2022 Jul; Vol. 298 (7), pp. 102148. Date of Electronic Publication: 2022 Jun 16.