Zobrazeno 1 - 10
of 260
pro vyhledávání: '"ML Cleary"'
Publikováno v:
Blood. 87:4607-4617
Genes encoding transcription factors are frequently altered by chromosomal translocations in acute lymphoblastic leukemia (ALL), suggesting that aberrant transcriptional regulation plays a prominent role in leukemogenesis. E2A-hepatic leukemia factor
Autor:
C deWolf-Peeters, B. Falini, Hk. Mullerhermelink, Dy. Mason, Sa Pileri, Es. Jaffe, Jkc. Chan, G. Delsol, Tm. Grogan, Ml. Cleary, Nl. Harris, Pm. Banks, Ra. Warnke, Dm. Knowles, Ma. Piris, Pg. Isaacson, Harald Stein, E. Ralfkiaer, K C Gatter
Publikováno v:
Blood. 85:857-860
Autor:
NL Harris, ES Jaffe, H Stein, PM Banks, JK Chan, ML Cleary, G Delsol, C De Wolf- Peeters, B Falini, KC Gatter
Publikováno v:
Blood. 84:1361-1392
Autor:
ML Cleary, AJ Carroll, DJ Pullen, JJ Shuster, Stephen P. Hunger, Michael J. Borowitz, CP Steuber
Publikováno v:
Blood. 82:1086-1091
The t(1;19)(q23;p13) translocation occurs in approximately 5% of B- precursor acute lymphoblastic leukemias (ALLs) occurring in children. Its presence has been associated with a poor prognosis, which may be overcome with more intensive therapy. Altho
Publikováno v:
Blood. 81:3197-3203
Chromosome band 11q23 is a site of recurrent translocations and interstitial deletions in human leukemias. Recent studies have shown that the 11q23 gene HRX is fused to heterologous genes from chromosomes 4 or 19 after t(4;11)(q21;q23) and t(11;19)(q
Publikováno v:
Blood. 84(6)
Chromosome band 11q23 is the site of recurring translocations with a variety of partner chromosomes in myeloid and lymphoid acute leukemias, infant leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints c
Publikováno v:
Blood. 84(2)
chromosome band 11q23, the location of the HRX gene, is a site of recurrent translocations in human malignancies. Infants with acute lymphoblastic leukemia (ALL) commonly have 11q23 translocations and have an especially poor prognosis despite intensi
Publikováno v:
Blood. 77(2)
To investigate the relationship of bcr-abl fusion mRNAs with childhood acute lymphoblastic leukemias (ALL), we examined 27 pediatric Philadelphia chromosome (Ph1)-positive acute leukemias using a reverse polymerase chain reaction (PCR) procedure. In
Autor:
S L Giardina, N Pritikin, David W. Golde, RK Oldham, J Sklar, Kenneth A. Foon, Robert W. Schroff, ML Cleary, CS Woodhouse
Publikováno v:
Blood. 66:1017-1021
Immunoglobulin gene rearrangement analysis and somatic cell hybridization techniques were used to examine the malignant cell population in an unusual patient with hairy cell leukemia and macroglobulinemia (N Engl J Med 296:92, 1977). Although previou
Publikováno v:
Blood. 73:2155-2164
We report the molecular, cytogenetic, and immunologic characterization of three hematologic malignancies that contained characteristic t(2;5) chromosomal translocations. The clinicopathologic features in all three cases fit the disease spectrum of so