Endogenous opioids modulate neuronal survival in the developing avian ciliary ganglion

Autor: Stephen D. Meriney, MJ Ford, G Pilar, D Oliva

Publikováno v: The Journal of Neuroscience. 11:3705-3717

Most studies on the trophic regulation of the normal neuronal competition for survival have focused on interactions between neurons and their target environment. However, it is also likely that trophic modulators are released from premotor inputs ont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5c43a87d99360ae719624b591954cf
https://doi.org/10.1523/jneurosci.11-12-03705.1991

Sensitization of colorectal and pancreatic cancer cell lines to the prodrug 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954) by retroviral transduction and expression of the E. coli nitroreductase gene

Autor: Nk, Green, Dj, Youngs, John Neoptolemos, Friedlos F, Rj, Knox, Cj, Springer, Gm, Anlezark, Np, Michael, Rg, Melton, Mj, Ford, Ls, Young, Dj, Kerr, Pf, Searle

Publikováno v: Europe PubMed Central

Expression of genes encoding prodrug-activating enzymes can increase the susceptibility of tumor cells to prodrugs, and may ultimately achieve a better therapeutic index than conventional chemotherapy. CB1954 is a weak, monofunctional alkylating agen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cc05eaf1c4392ea5f604f1e76548272a
https://pubmed.ncbi.nlm.nih.gov/9253508

Host proteins that bind to or mimic SV40 large T antigen: using antibodies to look at protein interactions and their significance

Autor: Sara Mole, Jv, Gannon, Ia, Anton, Mj, Ford, Dp, Lane

Publikováno v: Europe PubMed Central

The papovavirus SV40 is able to induce tumours in susceptible hosts and will transform cells in vitro. Its major early protein, large T antigen, is required for viral DNA synthesis, both in vivo and in vitro, and is also responsible for the oncogenic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::59ed0ef369376337b67ed16b763e27fb
http://europepmc.org/abstract/med/2478459

Natural TCRs targeting KRASG12V display fine specificity and sensitivity to human solid tumors.

Autor: Bear AS; Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine., Nadler RB; The College of Arts and Sciences., O'Hara MH; Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine.; Abramson Cancer Center, and., Stanton KL; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Xu C; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Saporito RJ; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Rech AJ; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Baroja ML; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Blanchard T; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Elliott MH; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Ford MJ; MSBioworks, Ann Arbor, Michigan, USA., Jones R; MSBioworks, Ann Arbor, Michigan, USA., Patel S; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Brennan A; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., O'Neil Z; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Powell DJ Jr; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Pathology and Laboratory Medicine and., Vonderheide RH; Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine.; Abramson Cancer Center, and.; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Linette GP; Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine.; Abramson Cancer Center, and.; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Carreno BM; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Pathology and Laboratory Medicine and.; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2024 Sep 17; Vol. 134 (21). Date of Electronic Publication: 2024 Sep 17.

A pan-respiratory antiviral chemotype targeting a transient host multi-protein complex.

Autor: Michon M; Prosetta Biosciences, San Francisco, CA, USA., Müller-Schiffmann A; Institute of Neuropathology, Heinrich Heine University, Düsseldorf, 40225 Germany., Lingappa AF; Prosetta Biosciences, San Francisco, CA, USA., Yu SF; Prosetta Biosciences, San Francisco, CA, USA., Du L; Vitalant Research Institute, San Francisco, CA, 94118-4417 USA., Deiter F; Veterans Administration Medical Center, San Francisco, CA, USA., Broce S; Prosetta Biosciences, San Francisco, CA, USA., Mallesh S; Prosetta Biosciences, San Francisco, CA, USA., Crabtree J; University of Georgia, Animal Health Research Center, Athens, GA, 28130 USA., Lingappa UF; Prosetta Biosciences, San Francisco, CA, USA., Macieik A; Prosetta Biosciences, San Francisco, CA, USA., Müller L; Institute of Virology, Heinrich Heine University, Düsseldorf, 40225 Germany., Ostermann PN; Institute of Virology, Heinrich Heine University, Düsseldorf, 40225 Germany., Andrée M; Institute of Virology, Heinrich Heine University, Düsseldorf, 40225 Germany., Adams O; Institute of Virology, Heinrich Heine University, Düsseldorf, 40225 Germany., Schaal H; Institute of Virology, Heinrich Heine University, Düsseldorf, 40225 Germany., Hogan RJ; Vitalant Research Institute, San Francisco, CA, 94118-4417 USA., Tripp RA; Vitalant Research Institute, San Francisco, CA, 94118-4417 USA., Appaiah U; Prosetta Biosciences, San Francisco, CA, USA., Anand SK; Santo Biotech, LLC, Pendleton, IN, USA., Campi TW; Santo Biotech, LLC, Pendleton, IN, USA., Ford MJ; MS Bioworks, Ann Arbor, MI, USA., Reed JC; Onipro LLC, Kensington, CA, USA., Lin J; Prosetta Biosciences, San Francisco, CA, USA., Akintunde O; Prosetta Biosciences, San Francisco, CA, USA., Copeland K; Prosetta Biosciences, San Francisco, CA, USA., Nichols C; Prosetta Biosciences, San Francisco, CA, USA., Petrouski E; Prosetta Biosciences, San Francisco, CA, USA., Moreira AR; Prosetta Biosciences, San Francisco, CA, USA., Jiang IT; Prosetta Biosciences, San Francisco, CA, USA., DeYarman N; Prosetta Biosciences, San Francisco, CA, USA., Brown I; Prosetta Biosciences, San Francisco, CA, USA., Lau S; Prosetta Biosciences, San Francisco, CA, USA., Segal I; Prosetta Biosciences, San Francisco, CA, USA., Goldsmith D; Prosetta Biosciences, San Francisco, CA, USA., Hong S; Prosetta Biosciences, San Francisco, CA, USA., Asundi V; Prosetta Biosciences, San Francisco, CA, USA., Briggs EM; Prosetta Biosciences, San Francisco, CA, USA., Phyo NS; Prosetta Biosciences, San Francisco, CA, USA., Froehlich M; Prosetta Biosciences, San Francisco, CA, USA., Onisko B; Onipro LLC, Kensington, CA, USA., Matlack K; Prosetta Biosciences, San Francisco, CA, USA., Dey D; Prosetta Biosciences, San Francisco, CA, USA., Lingappa JR; Department of Global Health, University of Washington, Seattle, WA, 98195, USA., Prasad DM; Prosetta Biosciences, San Francisco, CA, USA., Kitaygorodskyy A; Prosetta Biosciences, San Francisco, CA, USA., Solas D; Prosetta Biosciences, San Francisco, CA, USA., Boushey H; University of California, San Francisco, CA, 94143, USA., Greenland J; Veterans Administration Medical Center, San Francisco, CA, USA.; University of California, San Francisco, CA, 94143, USA., Pillai S; Vitalant Research Institute, San Francisco, CA, 94118-4417 USA.; University of California, San Francisco, CA, 94143, USA., Lo MK; Viral Special Pathogens Branch, US Centers for Disease Control and Prevention, Atlanta, GA, USA., Montgomery JM; Viral Special Pathogens Branch, US Centers for Disease Control and Prevention, Atlanta, GA, USA., Spiropoulou CF; Viral Special Pathogens Branch, US Centers for Disease Control and Prevention, Atlanta, GA, USA., Korth C; Institute of Neuropathology, Heinrich Heine University, Düsseldorf, 40225 Germany., Selvarajah S; Prosetta Biosciences, San Francisco, CA, USA., Paulvannan K; Prosetta Biosciences, San Francisco, CA, USA., Lingappa VR; Prosetta Biosciences, San Francisco, CA, USA.; University of California, San Francisco, CA, 94143, USA.

Publikováno v: Open biology [Open Biol] 2024 Jun; Vol. 14 (6), pp. 230363. Date of Electronic Publication: 2024 Jun 19.