Zobrazeno 1 - 10
of 460
pro vyhledávání: '"MJ Brodie"'
Publikováno v:
British Journal of Clinical Pharmacology. 23:358-361
Antipyrine kinetics following a single oral dose were obtained in porphyric patients in attack and in remission and in controls. The clearance of antipyrine was significantly lower during an acute porphyric attack (median: 0.34 ml min-1 kg-1; range:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b8715aff8bd561e9967b4a042f1eb7
https://doi.org/10.1111/j.1365-2125.1987.tb03059.x
https://doi.org/10.1111/j.1365-2125.1987.tb03059.x
Publikováno v:
British Journal of Clinical Pharmacology. 12:771-777
1 The metabolism of antipyrine to its three main oxidative metabolites, 4-hydroxyantipyrine, 3-hydroxymethylantipyrine and norphenazone was investigated in vivo and in vitro in separate groups of subjects with normal hepatic function and in the same
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7fe29bbb944983adf55758a1cbf996a
https://doi.org/10.1111/j.1365-2125.1981.tb01305.x
https://doi.org/10.1111/j.1365-2125.1981.tb01305.x
Publikováno v:
Scopus-Elsevier
1 Methods are described for the determination of mixed function oxidase activity in microsomal fractions from percutaneous needle biopsies of human liver. 2 Activities of needle biopsy samples were comparable with those of wedge biopsy sample obtaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2121df3ef3bd6415c3e2ae6dab86331
https://doi.org/10.1111/j.1365-2125.1980.tb04790.x
https://doi.org/10.1111/j.1365-2125.1980.tb04790.x
Autor:
Alan R. Boobis, Colin T. Dollery, R Harrison, MJ Brodie, EL Toverud, S Webster, W Ellis, Stephen Murray
Publikováno v:
British Journal of Clinical Pharmacology. 9:523-525
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f07650b59492cca7c2648e329a02ae9a
https://doi.org/10.1111/j.1365-2125.1980.tb05853.x
https://doi.org/10.1111/j.1365-2125.1980.tb05853.x
Publikováno v:
British Journal of Clinical Pharmacology. 11:89-91
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a2f092a689b173d1d43f26b1be9912
https://doi.org/10.1111/j.1365-2125.1981.tb01108.x
https://doi.org/10.1111/j.1365-2125.1981.tb01108.x
Autor:
Alan R. Boobis, Donald S. Davies, MJ Brodie, RY Frempong, C Whyte, Michael E. McManus, G. M. Pacifici, GC Kahn
Publikováno v:
Life sciences. 26(6)
The metabolism of xenobiotics by human lung has been investigated in tissue obtained from 10 patients undergoing pneumonectomy and compared with human liver activities in 6 different subjects. Lung microsomal fractions contain no detectable cytochrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec235fc99762b4297b915a6c4b20207
https://pubmed.ncbi.nlm.nih.gov/6768947
https://pubmed.ncbi.nlm.nih.gov/6768947
Publikováno v:
British journal of clinical pharmacology. 9(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64232315160851083c46553d970c4da1
https://pubmed.ncbi.nlm.nih.gov/7362740
https://pubmed.ncbi.nlm.nih.gov/7362740
Autor:
MJ Brodie
Publikováno v:
British journal of clinical pharmacology. 13(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abaf73557820605c4b90b121bb404f05
https://pubmed.ncbi.nlm.nih.gov/7066155
https://pubmed.ncbi.nlm.nih.gov/7066155
Autor:
JC Mucklow, MJ Brodie, CJ Hillyard, BK Park, EL Toverud, Donald S. Davies, I Macintyre, HS Fraser, Colin T. Dollery, PF Wilmana
Publikováno v:
British journal of clinical pharmacology. 8(6)
1 Twenty-four Asian vegetarians had significantly lower 25-hydroxyvitamin D (25-OHD) levels and longer antipyrine half-lives than twenty white non-vegetarians (P less than 0.001). 2 Treatment with oral antipyrine over 4 or 5 weeks in seven vegetarian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9966d8d8278436984c928b1f21d4f6c3
https://pubmed.ncbi.nlm.nih.gov/533574
https://pubmed.ncbi.nlm.nih.gov/533574
Publikováno v:
British journal of clinical pharmacology. 20(1)
Phenacetin O-deethylase activity was impaired, both in vivo and in vitro, in poor metabolisers of debrisoquine, consistent with the work of others. No impairment was observed in the oxidation of acetanilide, amylobarbitone or antipyrine in the PM phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6deb2d3f1b1eb1e429bdc0efd8779632
https://pubmed.ncbi.nlm.nih.gov/4027138
https://pubmed.ncbi.nlm.nih.gov/4027138