Zobrazeno 1 - 10
of 126
pro vyhledávání: '"MIchael Hackenberg"'
Autor:
Stavros Giannoukakos, Silvia D'Ambrosi, Danijela Koppers-Lalic, Cristina Gómez-Martín, Alberto Fernandez, Michael Hackenberg
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27360- (2024)
Liquid biopsy-derived RNA sequencing (lbRNA-seq) exhibits significant promise for clinic-oriented cancer diagnostics due to its non-invasiveness and ease of repeatability. Despite substantial advancements, obstacles like technical artefacts and proce
Externí odkaz:
https://doaj.org/article/153e3103597048f196f34257b9113a5d
Autor:
Monique A.J. van Eijndhoven, Chantal Scheepbouwer, Ernesto Aparicio-Puerta, Michael Hackenberg, D. Michiel Pegtel
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102645- (2023)
Summary: Besides canonical microRNAs (miRNAs), sequence-based variations called isomiRs have biological relevance and diagnostic potential; however, accurate calling of these post-transcriptional modifications is challenging, especially for low input
Externí odkaz:
https://doaj.org/article/f333a2f9af6b43af94de6e9a12fc66dd
Autor:
Diogo Fortunato, Stavros Giannoukakos, Ana Giménez-Capitán, Michael Hackenberg, Miguel A. Molina-Vila, Nataša Zarovni
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-24 (2022)
Abstract Background Intercellular communication is mediated by extracellular vesicles (EVs), as they enclose selectively packaged biomolecules that can be horizontally transferred from donor to recipient cells. Because all cells constantly generate a
Externí odkaz:
https://doaj.org/article/a32e0c24638f4896964ad6d0c176dec0
Digital multiplexed analysis of circular RNAs in FFPE and fresh non‐small cell lung cancer specimens
Autor:
Carlos Pedraz‐Valdunciel, Stavros Giannoukakos, Nicolas Potie, Ana Giménez‐Capitán, Chung‐Ying Huang, Michael Hackenberg, Alberto Fernandez‐Hilario, Jill Bracht, Martyna Filipska, Erika Aldeguer, Sonia Rodríguez, Trever G. Bivona, Sarah Warren, Cristina Aguado, Masaoki Ito, Andrés Aguilar‐Hernández, Miguel Angel Molina‐Vila, Rafael Rosell
Publikováno v:
Molecular Oncology, Vol 16, Iss 12, Pp 2367-2383 (2022)
Although many studies highlight the implication of circular RNAs (circRNAs) in carcinogenesis and tumor progression, their potential as cancer biomarkers has not yet been fully explored in the clinic due to the limitations of current quantification m
Externí odkaz:
https://doaj.org/article/80cef2ed33524c79919697a56c94f2dd
Autor:
José María Medina, Mohamed Amine Jmel, Brent Cuveele, Cristina Gómez-Martín, Ernesto Aparicio-Puerta, Imen Mekki, Jan Kotál, Larissa Almeida Martins, Michael Hackenberg, Chaima Bensaoud, Michail Kotsyfakis
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Ticks are blood-feeding arthropods that use the components of their salivary glands to counter the host’s hemostatic, inflammatory, and immune responses. The tick midgut also plays a crucial role in hematophagy. It is responsible for managing blood
Externí odkaz:
https://doaj.org/article/17ae4b4aacc142e19e1b26054b57edae
Autor:
Silvia D’Ambrosi, Stavros Giannoukakos, Mafalda Antunes-Ferreira, Carlos Pedraz-Valdunciel, Jillian W. P. Bracht, Nicolas Potie, Ana Gimenez-Capitan, Michael Hackenberg, Alberto Fernandez Hilario, Miguel A. Molina-Vila, Rafael Rosell, Thomas Würdinger, Danijela Koppers-Lalic
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4881 (2023)
Despite the diversity of liquid biopsy transcriptomic repertoire, numerous studies often exploit only a single RNA type signature for diagnostic biomarker potential. This frequently results in insufficient sensitivity and specificity necessary to rea
Externí odkaz:
https://doaj.org/article/508b8d699bbb4150bd895b6180ff88bf
Autor:
Cristina Gómez-Martín, Hui Zhou, José María Medina, Ernesto Aparicio-Puerta, Bujun Shi, Michael Hackenberg
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 440 (2023)
Wheat is one of the most important food sources on Earth. MicroRNAs (miRNAs) play important roles in wheat productivity. To identify wheat miRNAs as well as their expression profiles under drought condition, we constructed and sequenced small RNA (sR
Externí odkaz:
https://doaj.org/article/fd06d843712a47a09839abfc8c2b0f06
Autor:
Ana M. González, Ricardo Lebrón, Fernando J. Yuste-Lisbona, Cristina Gómez-Martín, Ana Ortiz-Atienza, Michael Hackenberg, José L. Oliver, Rafael Lozano, Marta Santalla
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14783 (2022)
The tropical common bean (Phaseolus vulgaris L.) is an obligatory short-day plant that requires relaxation of the photoperiod to induce flowering. Similar to other crops, photoperiod-induced floral initiation depends on the differentiation and mainte
Externí odkaz:
https://doaj.org/article/55c48853c3fc484e8bd07eaf30a7d80b
Autor:
Carlos Pedraz-Valdunciel, Stavros Giannoukakos, Ana Giménez-Capitán, Diogo Fortunato, Martyna Filipska, Jordi Bertran-Alamillo, Jillian W. P. Bracht, Ana Drozdowskyj, Joselyn Valarezo, Natasa Zarovni, Alberto Fernández-Hilario, Michael Hackenberg, Andrés Aguilar-Hernández, Miguel Ángel Molina-Vila, Rafael Rosell
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2034 (2022)
Background: The analysis of liquid biopsies brings new opportunities in the precision oncology field. Under this context, extracellular vesicle circular RNAs (EV-circRNAs) have gained interest as biomarkers for lung cancer (LC) detection. However, st
Externí odkaz:
https://doaj.org/article/4b768aff04134ca0a6c572a1e40f25df
Autor:
Esther E. E. Drees, Margaretha G. M. Roemer, Nils J. Groenewegen, Jennifer Perez‐Boza, Monique A. J. vanEijndhoven, Leah I. Prins, Sandra A. W. M. Verkuijlen, Xuan‐Mai Tran, Julia Driessen, G. J. C. Zwezerijnen, Phylicia Stathi, Kevin Mol, Joey J. J. P. Karregat, Aikaterini Kalantidou, Andrea Vallés‐Martí, T. J. Molenaar, Ernesto Aparicio‐Puerta, Erik vanDijk, Bauke Ylstra, Catharina G. M. Groothuis‐Oudshoorn, Michael Hackenberg, Daphne deJong, Josée M. Zijlstra, D. Michiel Pegtel
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 9, Pp n/a-n/a (2021)
Abstract Minimally‐invasive tools to assess tumour presence and burden may improve clinical management. FDG‐PET (metabolic) imaging is the current gold standard for interim response assessment in patients with classical Hodgkin Lymphoma (cHL), bu
Externí odkaz:
https://doaj.org/article/dd7ff80e47294223ac9069d292d8a4bd