Zobrazeno 1 - 10
of 1 245
pro vyhledávání: '"MITOCHONDRIAL TRANSFER"'
Unveiling the power of mitochondrial transfer in cancer progression: a perspective in ovarian cancer
Autor:
Caixia Wang, Chuan Xie
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Mitochondria are dynamic organelles integral to metabolic processes, coordination of essential biological pathways, and oncogenesis and tumor progression. Recent studies have revealed that mitochondria can be transferred between cells via mu
Externí odkaz:
https://doaj.org/article/21ca235d3ff141c7a7266a466c4e20e9
Autor:
Minghang Zhang, Junfeng Wu, Kehan Cai, Yang Liu, Botao Lu, Jiaojiao Zhang, Jianzhong Xu, Chenxi Gu, Tao Chen
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Osteoarthritis (OA) is a chronic degenerative joint condition characterised by cartilage deterioration and changes in bone morphology, resulting in pain and impaired joint mobility. Investigation into the pathophysiological mechanisms underl
Externí odkaz:
https://doaj.org/article/d1688e654ac241488abf87e5a25d46d8
Autor:
Loic Vaillant, Waseem Akhter, Jean Nakhle, Matthieu Simon, Martin Villalba, Christian Jorgensen, Marie-Luce Vignais, Javier Hernandez
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background . CD8+ Cytotoxic T lymphocytes play a key role in the pathogenesis of autoimmune diseases and clinical conditions such as graft versus host disease and graft rejection. Mesenchymal Stromal Cells (MSCs) are multipotent cells with t
Externí odkaz:
https://doaj.org/article/3fbbf7d8d6cb4553818e55ee8beab49b
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-26 (2024)
Abstract To assess the efficacy of a novel 3D biomimetic hydrogel scaffold with immunomodulatory properties in promoting fracture healing. Immunomodulatory scaffolds were used in cell experiments, osteotomy mice treatment, and single-cell transcripto
Externí odkaz:
https://doaj.org/article/3a7adfbbdf6549bd8f4c3a94345bbf6c
Autor:
Zikril Ariliusra
Publikováno v:
Majalah Kedokteran Andalas, Vol 46, Iss 9, Pp 1469-1481 (2024)
Transfer mitokondria interseluler diduga dapat menjadi mekanisme terapi mesenchymal stem cell (MSC) terhadap berbagai penyakit yang diakibatkan oleh gangguan atau kerusakan pada mitokondria, salah satunya kardiomiopati akibat doxorubicin. Tujuan pene
Externí odkaz:
https://doaj.org/article/bc12ed8a98424efb948b85e84a92f022
Autor:
Vitale Del Vecchio, Ayesha Rehman, Sameer Kumar Panda, Martina Torsiello, Martina Marigliano, Maria Maddalena Nicoletti, Giuseppe Andrea Ferraro, Vincenzo De Falco, Rosamaria Lappano, Eva Lieto, Francesca Pagliuca, Carlo Caputo, Marcella La Noce, Gianpaolo Papaccio, Virginia Tirino, Nirmal Robinson, Vincenzo Desiderio, Federica Papaccio
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Breast cancer (BC) is a complex disease, showing heterogeneity in the genetic background, molecular subtype, and treatment algorithm. Historically, treatment strategies have been directed towards cancer cells, but these are not th
Externí odkaz:
https://doaj.org/article/3a0b4cf17b544ce2a70d5d0c9f16b631
Autor:
Wenjin Cai, Shihua Mao, Ying Wang, Bicong Gao, Jiaying Zhao, Yongzheng Li, Yani Chen, Dong Zhang, Jintao Yang, Guoli Yang
Publikováno v:
Advanced Science, Vol 11, Iss 42, Pp n/a-n/a (2024)
Abstract Coordinating the immune response and bioenergy metabolism in bone defect environments is essential for promoting bone regeneration. Mitochondria are important organelles that control internal balance and metabolism. Repairing dysfunctional m
Externí odkaz:
https://doaj.org/article/eb324d6292684cbeb5b8e85b3eeba5f2
Publikováno v:
Neurobiology of Disease, Vol 201, Iss , Pp 106681- (2024)
Lenadogene nolparvovec is a gene therapy which has been developed to treat Leber hereditary optic neuropathy (LHON) caused by a point mutation in the mitochondrial NADH dehydrogenase 4 (ND4) gene. Clinical trials have demonstrated a significant impro
Externí odkaz:
https://doaj.org/article/254ba0f4562143f28a868d12e6c4e99d
Autor:
Huacui Xiong, Huanhuan Qiu, Chunhui Wang, Yonghao Qiu, Shuyi Tan, Ke Chen, Fujian Zhao, Jinlin Song
Publikováno v:
Materials Today Bio, Vol 28, Iss , Pp 101175- (2024)
The repair of bone defects in the elderly individuals is significantly delayed due to cellular senescence and dysfunction, which presents a challenge in clinical settings. Furthermore, there are limited effective methods available to promote bone rep
Externí odkaz:
https://doaj.org/article/2a8a40667a434fb0800fc7022c7bff42
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Intercellular mitochondrial transfer (MT) is a newly discovered form of cell-to-cell signalling involving the active incorporation of healthy mitochondria into stressed/injured recipient cells, contributing to the restoration of bioenergetic
Externí odkaz:
https://doaj.org/article/f1943cfebabe4db58aac6d09a7cb12c0