Zobrazeno 1 - 10
of 49
pro vyhledávání: '"MITO-QC"'
Akademický článek
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Autor:
Francois Singh, Alan R Prescott, Philippa Rosewell, Graeme Ball, Alastair D Reith, Ian G Ganley
Publikováno v:
eLife, Vol 10 (2021)
Parkinson’s disease (PD) is a major and progressive neurodegenerative disorder, yet the biological mechanisms involved in its aetiology are poorly understood. Evidence links this disorder with mitochondrial dysfunction and/or impaired lysosomal deg
Externí odkaz:
https://doaj.org/article/1fe20ff9e4834b2f99a5c0d252b7aa97
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Ines Rosignol, Beatriz Villarejo-Zori, Petra Teresak, Elena Sierra-Filardi, Xandra Pereiro, Natalia Rodríguez-Muela, Elena Vecino, Helena L. A. Vieira, Katharina Bell, Patricia Boya
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1882 (2020)
Mitochondrial damage plays a prominent role in glaucoma. The only way cells can degrade whole mitochondria is via autophagy, in a process called mitophagy. Thus, studying mitophagy in the context of glaucoma is essential to understand the disease. Up
Externí odkaz:
https://doaj.org/article/7209aa92a4184ca0b6fba591b4a87101
Autor:
Rappe, Anna, McWilliams, Thomas G.
Aging is characterised by the progressive accumulation of cellular dysfunction, stress, and inflammation. A large body of evidence implicates mitochondrial dysfunction as a cause or consequence of age-related diseases including metabolic disorders, n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1593::16f3a0de636429b79e11a3d6a9eded5a
http://hdl.handle.net/10138/350817
http://hdl.handle.net/10138/350817
Autor:
Hsu, Lewis Shun-Neng
Chronic kidney disease (CKD) is an irreversible systemic disease characterised by the gradual loss of kidney function over time. Patients with progressive CKD frequently encounter altered levels of circulating and bone-derived hormones which can dysr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______463::3c5986e62d4d8b0c05b63db18078589c
https://hdl.handle.net/1842/39136
https://hdl.handle.net/1842/39136
Autor:
Maeve Long, Thomas G. McWilliams
Publikováno v:
Seminars in Cancer Biology. 66:12-21
Autophagy refers to an essential mechanism that evolved to sustain eukaryotic homeostasis and metabolism during instances of nutrient deprivation. During autophagy, intracellular cargo is encapsulated and delivered to the lysosome for elimination. Lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccfdcca9b5dee98a4d10050915ab6ab4
https://doi.org/10.1016/j.semcancer.2019.05.016
https://doi.org/10.1016/j.semcancer.2019.05.016
Autor:
Long, Maeve, Sanchez-Martinez, Alvaro, Longo, Marianna, Suomi, Fumi, Stenlund, Hans, Johansson, Annika I, Ehsan, Homa, Salo, Veijo T, Montava-Garriga, Lambert, Naddafi, Seyedehshima, Ikonen, Elina, Ganley, Ian G, Whitworth, Alexander J, McWilliams, Thomas G
Funder: Novo Nordisk Foundation/Novo Nordisk Fonden; Id: http://dx.doi.org/10.13039/501100011747
Funder: Helsingin Yliopisto (HY); Id: http://dx.doi.org/10.13039/100007797
Funder: Sydäntutkimussäätiö (Finnish Foundation for Cardiovascul
Funder: Helsingin Yliopisto (HY); Id: http://dx.doi.org/10.13039/100007797
Funder: Sydäntutkimussäätiö (Finnish Foundation for Cardiovascul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::562d4701cc356047a7c147af849e5782
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-193974
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-193974
Autor:
Alan R. Prescott, Philippa Rosewell, Ian G. Ganley, Graeme Ball, Alastair D. Reith, François Singh
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Parkinson’s disease (PD) is a major and progressive neurodegenerative disorder, yet the biological mechanisms involved in its aetiology are poorly understood. Evidence links this disorder with mitochondrial dysfunction and/or impaired lysosomal deg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6415a524a8c36dd76f9496bbe9760360
https://elifesciences.org/articles/67604
https://elifesciences.org/articles/67604
Autor:
McWilliams, Thomas G., Prescott, Alan R., Villarejo-Zori, Beatriz, Ball, Graeme, Boya, Patricia, Ganley, Ian G.
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
14 p.-6 fig.
Photoreception is pivotal to our experience and perception of the natural world; hence the eye is of prime importance for most vertebrate animals to sense light. Central to visual health is mitochondrial homeostasis, and the selecti
Photoreception is pivotal to our experience and perception of the natural world; hence the eye is of prime importance for most vertebrate animals to sense light. Central to visual health is mitochondrial homeostasis, and the selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7c2091371194bf03f7db0014da1fc34b
http://hdl.handle.net/10138/306378
http://hdl.handle.net/10138/306378