Zobrazeno 1 - 10
of 30
pro vyhledávání: '"MITA VARGHESE"'
Autor:
Mita Varghese, Jeremy Clemente, Arianna Lerner, Simin Abrishami, Mohammed Islam, Perla Subbaiah, Kanakadurga Singer
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Obesity is associated with systemic inflammation and immune cell recruitment to metabolic tissues. Sex differences have been observed where male mice challenged with high fat diet (HFD) exhibit greater adipose tissue inflammation than females demonst
Externí odkaz:
https://doaj.org/article/6df4a0e44b1641e89410d0c64acb5e19
Autor:
Cameron Griffin, Chelsea R. Hutch, Simin Abrishami, Daria Stelmak, Leila Eter, Ziru Li, Eric Chang, Devyani Agarwal, Brian Zamarron, Mita Varghese, Perla Subbaiah, Ormond A. MacDougald, Darleen A. Sandoval, Kanakadurga Singer
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-16 (2019)
Abstract Background Weight loss by surgery or lifestyle changes is strongly recommended for obese individuals to improve metabolic health, but the underlying impairments that persist from a history of obesity remain unclear. Recent investigations dem
Externí odkaz:
https://doaj.org/article/0eb8f96c2ae3414c8d70662c2c7f319d
Publikováno v:
International Journal of Cell Biology, Vol 2012 (2012)
A computerized morphometric classification technique based on latent factors reveals major protrusion classes: factors 4, 5, and 7. Previous work showed that factor 4 represented filopodia, 5 the distribution of lamellar cytoplasm, and 7 a blunt prot
Externí odkaz:
https://doaj.org/article/e51a7a665ead4425a80fc6075597f64d
Age‐associated adipose tissue inflammation promotes monocyte chemotaxis and enhances atherosclerosis
Autor:
Jianrui Song, Diana Farris, Paola Ariza, Smriti Moorjani, Mita Varghese, Muriel Blin, Judy Chen, Daniel Tyrrell, Min Zhang, Kanakadurga Singer, Morgan Salmon, Daniel R. Goldstein
Publikováno v:
Aging Cell. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f73b07d4f05e4ae93b3104ec628ac7cf
https://doi.org/10.1111/acel.13783
https://doi.org/10.1111/acel.13783
Autor:
Simin Abrishami, Mita Varghese, Jason S Villano, Mohammed R Islam, Kanakadurga Singer, Kimberly A Schultz
Publikováno v:
J Am Assoc Lab Anim Sci
Understanding how differences in animal husbandry practices affect the reproducibility of research results is critical. We sought to understand how different beddings might influence dietary obesity studies. We compared the effects of paper and cornc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d1e5ea95a9cb6717e84423324aed39
https://doi.org/10.30802/aalas-jaalas-20-000139
https://doi.org/10.30802/aalas-jaalas-20-000139
Publikováno v:
Diabetes. 71
Obesity-induced inflammation is a risk factor for metabolic impairment leading to diabetes and cardiovascular disease. We, and others, have shown that sex differences exist in adipose tissue (AT) and myeloid inflammatory responses to high-fat diet (H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e0f32e1cda7635e39a4ef2227af2adb
https://doi.org/10.2337/db22-236-lb
https://doi.org/10.2337/db22-236-lb
Autor:
Mita Varghese, Kaitlin McKernan, Simin Abrishami, Leila Eter, Kanakadurga Singer, Cameron Griffin
Publikováno v:
Aging (Albany NY)
Aging, like obesity, is associated with metabolic and inflammatory alterations within adipose tissue in older individuals. Younger females are protected from adipose inflammation, but older post-menopausal females exhibit exaggerated visceral adiposi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377350b9527f89bcd39095cef3fd6a70
https://doi.org/10.18632/aging.102709
https://doi.org/10.18632/aging.102709
Autor:
Mita Varghese, Jeremy Clemente, Arianna Lerner, Simin Abrishami, Mohammed Islam, Perla Subbaiah, Kanakadurga Singer
Publikováno v:
Frontiers in endocrinology. 13
Obesity is associated with systemic inflammation and immune cell recruitment to metabolic tissues. Sex differences have been observed where male mice challenged with high fat diet (HFD) exhibit greater adipose tissue inflammation than females demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38c7f10df1ba451ff903eccc5002feb
https://pubmed.ncbi.nlm.nih.gov/35422759
https://pubmed.ncbi.nlm.nih.gov/35422759
Autor:
James G. Granneman, Mita Varghese, Guy Perkins, Fariha R. Ghazi, Victoria A. Kimler, Mark H. Ellisman, Gurnoor K. Rathore
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
This study investigated the effects of elevated fatty acid (FA) supply from adipose tissue on the ultrastructure of cardiac lipid droplets (LDs) and the expression and organization of LD scaffold proteins perilipin-2 (PLIN2) and perilipin-5 (PLIN5).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f801324ae7754b987d6d1f5a0da938
http://link.springer.com/article/10.1038/s41598-019-41329-4
http://link.springer.com/article/10.1038/s41598-019-41329-4
Autor:
Omolola Eniola-Adefeso, Kanakadurga Singer, Hanieh Safari, Mita Varghese, Emma R. Brannon, Nicholas Kaczorowski, Michael L. Felder
Publikováno v:
Science Advances
We describe a novel gold-templating method for fabricating stable, biodegradable, bile salt microparticles with controlled geometry.
Bile acids are proposed as therapeutic agents for various diseases, including liver diseases and obesity. Howeve
Bile acids are proposed as therapeutic agents for various diseases, including liver diseases and obesity. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e58aca44a694a0b9e95aeb6b36a63f1
https://doi.org/10.1126/sciadv.abd8019
https://doi.org/10.1126/sciadv.abd8019