Zobrazeno 1 - 10
of 715
pro vyhledávání: '"MIR-101"'
Autor:
Randa Erfan, Olfat G. Shaker, Mahmoud A.F. Khalil, Amel Raouf Hassan, Abeer K. Abu-El-Azayem, Amira Samy, Haitham Abdelhamid, Aeshah A. Awaji, Hassan Salem El sayed, Asmaa Mohammed
Publikováno v:
Non-coding RNA Research, Vol 10, Iss , Pp 35-40 (2025)
Background: Alopecia areata (AA) commonly displays as non-scarring, irregular hair loss. Experimental and clinical research have specifically implicated autoimmunity and genetics in the disruption of anagen hair follicles. AA patients' scalp lesions
Externí odkaz:
https://doaj.org/article/fcedd7aaf9a24d51a9cf3873ede44464
Publikováno v:
Renal Failure, Vol 46, Iss 1 (2024)
Acute kidney injury (AKI) can progress to renal fibrosis and chronic kidney disease (CKD), which reduces quality of life and increases the economic burden on patients. However, the molecular mechanisms underlying renal fibrosis following AKI remain u
Externí odkaz:
https://doaj.org/article/198aa8fe6e084ed18b5aca0d7aab66e7
Autor:
E. I. Dzhugashvili, N. V. Yunusova, A. I. Yalovaya, A. E. Grigorieva, E. E. Sereda, L. A. Kolomiets, S. N. Tamkovich
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 2, Pp 108-116 (2023)
Introduction. Ovarian cancer (OC) is one of the malignant neoplasms of the female reproductive system with a high mortality rate. Currently used tumor markers of this pathology do not have high sensitivity and specificity. In this regard, promising a
Externí odkaz:
https://doaj.org/article/67676fadb8694bcb88f069965e0af4d0
Publikováno v:
Cancer Biology & Therapy, Vol 24, Iss 1 (2023)
Introduction Sirtuin 1 (SIRT1) is a key modulator in several types of cancer, including colorectal cancer (CRC). Here, we probed into the molecular mechanism of SIRT1 regulating the development and chemoresistance of CRC. Methods Differentially expre
Externí odkaz:
https://doaj.org/article/f1939b75f213432aa2ab29174fd186fe
Publikováno v:
Clinical and Experimental Hypertension, Vol 44, Iss 8, Pp 671-677 (2022)
Objectives This study explored the miR-101 clinical significance in hypertensive disorder complicating pregnancy (HDCP). Methods Pregnant women with gestational hypertension (GH)/mild preeclampsia (mPE)/severe preeclampsia (sPE) were included. The mi
Externí odkaz:
https://doaj.org/article/fdf9f826677743018aab6f34b44b1338
Publikováno v:
BMC Urology, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background NEAT1 has been shown to play an oncogenic role in many kinds of cancers. However, detailed roles of NEAT1 in bladder cancer are largely unknown. Methods In the present study, the expression of NEAT1, miR-101 and VEGF-C was detecte
Externí odkaz:
https://doaj.org/article/78e5249d198e492cae3178586e3fff80
Autor:
Hang-fei Chen, Dan-dan Gao, Xin-qing Jiang, Hao Sheng, Qi Wu, Quan Zheng, Qiao-cheng Zhai, Lei Yuan, Ming Liu, Li-feng Xu, Mao-xiang Qian, Heng Xu, Jian Fang, Feng Zhang
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundTAF1B (TATA Box Binding Protein (TBP)-Associated Factor) is an RNA polymerase regulating rDNA activity, stress response, and cell cycle. However, the function of TAF1B in the progression of hepatocellular carcinoma (HCC) is unknown.Objectiv
Externí odkaz:
https://doaj.org/article/6658ca29664c4e6d8978c816dab993fe
Autor:
Yang Feng, Jingjing Ge, Danying Zhang, Xue Bai, Hongming Fang, Yujuan Zhou, Wanlin Che, Wenxuan Zhang, Ruixia Zhao, Zuchun Qiu, Xuewei Zhao, Li Xiao, Huimin He, Sinan Cheng, Wei Duan, Ruiju Wang, Wei Chen, Guochao Nie, Yingchun Hou
Publikováno v:
Materials Today Advances, Vol 19, Iss , Pp 100407- (2023)
Esophageal squamous cell carcinoma (ESCC) is one of the most popular cancers in digestive tract. Chemotherapy is still the primary treatment for ESCC patients with or without surgery. But the efficacy of the current chemotherapy for ESCC is poor with
Externí odkaz:
https://doaj.org/article/6a5fdf0bc07a4d8883a274798fe72a00
Publikováno v:
Jichu yixue yu linchuang, Vol 42, Iss 3, Pp 472-478 (2022)
Objective To explore the function of circ-MALAT1 targeting miR-101 in the inhibition of the invasion and migration of bladder cancer cells. Methods Bladder cancer cell line SW780 was divided into si-NC group (transfection si-NC), si-circ-MALAT1 group
Externí odkaz:
https://doaj.org/article/8984fa29891c4ab99cf3dffe8284e473
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The leading pathological mechanisms of Alzheimer’s disease (AD) are amyloidosis and chronic inflammation. The study of new therapeutic drugs of the corresponding action, in particular miRNAs and curcominoids, as well as methods for their packaging,
Externí odkaz:
https://doaj.org/article/594e371937cd44609ebcb24ba2e5f24a