Zobrazeno 1 - 10
of 69
pro vyhledávání: '"MINEO NIWA"'
Autor:
Masayuki Fukuda, Takeshi Yagami, Yukio Sugiura, Masayuki Omote, Kayoko Yamauchi, Mineo Niwa, Shiroh Futaki
Publikováno v:
Journal of the American Chemical Society. 123:12127-12134
In this report, we describe a novel concept of extramembrane control of channel peptide assembly and the eventual channel current modulation. Alamethicin is a peptide antibiotic, which usually forms ion channels in various association states. By intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a685a5f1d82612ccc20329443bfff8b
https://doi.org/10.1021/ja011166i
https://doi.org/10.1021/ja011166i
Publikováno v:
Bulletin of the Chemical Society of Japan. 72:1827-1835
The primary structure of human IGF-I, except for the disulfide bond system, has been reported by Rinderknecht and Humbel. IGF-I afforded the corresponding characteristic peptide fragments on V8 protease digestion, which contained Cys6, Cys47, Cys48,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be2825f367aa72be9beaf776eb2bc300
https://doi.org/10.1246/bcsj.72.1827
https://doi.org/10.1246/bcsj.72.1827
Autor:
Tomoko Ishikawa, Mineo Niwa, Shiroh Futaki, Tomoko Asahara, Kouki Kitagawa, Fusayo Kondo, Takeshi Yagami, Yutaka Nakaya, Mika Aoki
Publikováno v:
Bioorganic & Medicinal Chemistry. 7:187-192
Development of the strategies for assembling multiple kinds of peptide segments would give new possibilities for the de novo design of functional proteins. We will introduce our approach for the selective assembly of helical peptide segments on a pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4d0ab279025c5d65fe8ba7189ea7a7
https://doi.org/10.1016/s0968-0896(98)00246-6
https://doi.org/10.1016/s0968-0896(98)00246-6
Autor:
Mineo Niwa, Hiroshi Kiwada, S. Futaki, Hideyoshi Harashima, Makiko Azumano, Rieko Tachibana, Masayuki Shono
Publikováno v:
Biochemical and Biophysical Research Communications. 251:538-544
The objective of this study is to present a rational strategy to target macromolecules to the nucleus via the endocytic pathway. The two major barriers in this route to the nucleus are known as endosomal escape and nuclear transport. pH-sensitive lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56da8875a27688081953a2926196e484
https://doi.org/10.1006/bbrc.1998.9460
https://doi.org/10.1006/bbrc.1998.9460
Autor:
Keiko Kitajima, Shiroh Futaki, Noriko Nakamura, Mari Ueda, Yoshihisa Takaishi, Yasuyuki Tsutsumishita, Mineo Niwa
Publikováno v:
Biochemical and Biophysical Research Communications. 239:367-371
Benzoquinones inhibited the production of NO induced by LPS and γ-IFN in C6 glia cells. The mechanistic studies showed that benzoquinones inhibited the expression of iNOS mRNA through inactivation of NF κ B. Benzoquinones may be a useful candidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14261377cf2d33ce58330aa5c173fe42
https://doi.org/10.1006/bbrc.1997.7437
https://doi.org/10.1006/bbrc.1997.7437
Autor:
Masayuki Fukuda, Fusayo Kondo, Mika Aoki, Yutaka Nakaya, Mineo Niwa, Shiroh Futaki, Kouki Kitagawa
Publikováno v:
Tetrahedron Letters. 38:7071-7074
A template having four cysteines with selectively detachable protecting groups was developed, which enables selective introduction of individual helices by chemical ligation between the free sulfhydryl group on the template and the chloroacetyl moiet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad7085b54b0c0f32ea716ff66be4807b
https://doi.org/10.1016/s0040-4039(97)01651-1
https://doi.org/10.1016/s0040-4039(97)01651-1
Publikováno v:
Bioorganic & Medicinal Chemistry. 5:1883-1891
A new approach was developed to embody the alpha-helical protein structure having an arbitrary combination and arrangement of helices by the successive ligation of a haloacetyl peptide segment with a cysteinyl peptide. A four-helix-bundle protein was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6a04e302eefad718e7673a937aa1fc
https://doi.org/10.1016/s0968-0896(97)00119-3
https://doi.org/10.1016/s0968-0896(97)00119-3
Publikováno v:
Tetrahedron Letters. 38:6237-6240
Preparation of peptide thioesters was conducted through peptide chain construction with Fmoc-solid-phase peptide synthesis on a 2-chlorotrityl resin followed by coupling with HS-(CH2)2-COOEt and deprotection with 95% aqueous CF3COOH. The peptide thio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c5d1c137475f19589011c670f033c5b
https://doi.org/10.1016/s0040-4039(97)01434-2
https://doi.org/10.1016/s0040-4039(97)01434-2
Autor:
Mineo Niwa, Takao Fujimura, Hitoshi Sasaki, Hisashi Yamada, Yuji Noguchi, Yoshimasa Saito, Kyoichi Shimomura, Yoshinori Ishii
Publikováno v:
Annals of the New York Academy of Sciences. 782:226-240
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e1d96e1f323172d042318c020dbd78
https://doi.org/10.1111/j.1749-6632.1996.tb40564.x
https://doi.org/10.1111/j.1749-6632.1996.tb40564.x
Autor:
Kenji Katoh, Takaaki Ikata, Mineo Niwa, Yasuyuki Tsutsumishita, Shinsuke Katoh, Yoshitaka Hamada, Kenji Fukuzawa
Publikováno v:
Neuroscience Letters. 203:97-100
This study was undertaken to examine the effect of transforming growth factor-beta 1 (TGF-beta 1) administered into the subarachnoid space after spinal cord injury (SCI) on the increased production of inducible-nitric oxide synthase (i-NOS) in the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f99f5719b450eb46750c7742804280
https://doi.org/10.1016/0304-3940(95)12271-0
https://doi.org/10.1016/0304-3940(95)12271-0