Is Beta-Amyloid Accumulation a Cause or Consequence of Alzheimer’s Disease?

Autor: Wang, Shaoxun, Mims, Paige N., Roman, Richard J., Fan, Fan

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized by the pathological hallmarks of extracellular beta-amyloid (Aβ) plaques and intraneuronal tau-containing neurofibrillary tangles in the brain. Intraneuronal

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https://europepmc.org/articles/PMC5555607/

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Impaired Cerebral Autoregulation-A Common Neurovascular Pathway in Diabetes may Play a Critical Role in Diabetes-Related Alzheimer's Disease.

Autor: Shekhar S; Department of Neurology, University of Mississippi Medical Center, USA.; Institute of Clinical Medicine, University of Turku, Finland., Wang S; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, USA., Mims PN; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, USA., Gonzalez-Fernandez E; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, USA., Zhang C; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, USA.; Department of Urology, Fudan University, China., He X; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, USA., Liu CY; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, USA., Lv W; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, USA.; Department of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, China., Wang Y; Department of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, China., Huang J; Department of Neurology, University of Mississippi Medical Center, USA., Fan F; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, USA.

Publikováno v: Current research in diabetes & obesity journal [Curr Res Diabetes Obes J] 2017 Jun; Vol. 2 (3). Date of Electronic Publication: 2017 Jun 05.