Zobrazeno 1 - 10 of 40 pro vyhledávání: '"MIKI TSUJITA"'
1
Akademický článek
Effects of rs958804 and rs7858836 single‐nucleotide polymorphisms of the ASTN2 gene on pain‐related phenotypes in patients who underwent laparoscopic colectomy and mandibular sagittal split ramus osteotomy
Autor: Rie Inoue, Daisuke Nishizawa, Junko Hasegawa, Kyoko Nakayama, Ken‐ichi Fukuda, Tatsuya Ichinohe, Tsutomu Mieda, Miki Tsujita, Hideyuki Nakagawa, Akira Kitamura, Hiroyuki Sumikura, Kazutaka Ikeda, Masakazu Hayashida
Publikováno v: Neuropsychopharmacology Reports, Vol 41, Iss 1, Pp 82-90 (2021)
Abstract Background Opioids are widely used as effective analgesics, but opioid sensitivity varies widely among individuals. The underlying genetic and nongenetic factors are not fully understood. Based on the results of our previous genome‐wide as
Externí odkaz: https://doaj.org/article/87bbe8338dbf402a824e897ea0ff720b
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2
Akademický článek
Donepezil reverses buprenorphine-induced central respiratory depression in anesthetized rabbits
Autor: SHIGEKI SAKURABA, MIKI TSUJITA, HIROFUMI ARISAKA, JUNZO TAKEDA, KAZUICHI YOSHIDA, SHUN-ICHI KUWANA
Publikováno v: Biological Research, Vol 42, Iss 4, Pp 469-475 (2009)
Buprenorphine is a mixed opioid receptor agonist-antagonist used in acute and chronic pain management. Although this agent's analgesic effect increases in a dose-dependent manner, buprenorphine-induced respiratory depression shows a marked ceiling ef
Externí odkaz: https://doaj.org/article/bfd8935ebeff41478d4c6518c51d9d37
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3
Akademický článek
Antagonism of morphine-induced central respiratory depression by donepezil in the anesthetized rabbit
Autor: MIKI TSUJITA, SHIGEKI SAKURABA, JUNYA KURIBAYASHI, YUKI HOSOKAWA, EIKI HATORI, YASUMASA OKADA, MASANORI KASHIWAGI, JUNZO TAKEDA, SHUN-ICHI KUWANA
Publikováno v: Biological Research, Vol 40, Iss 3, Pp 339-346 (2007)
Morphine is often used in cancer pain and postoperative analgesic management but induces respiratory depression. Therefore, there is an ongoing search for drug candidates that can antagonize morphine-induced respiratory depression but have no effect
Externí odkaz: https://doaj.org/article/16266b046cb84d7b9f29ded23a8741da
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4
Akademický článek
Association of nicotinic acetylcholine receptors with central respiratory control in isolated brainstem-spinal cord preparation of neonatal rats
Autor: EIKI HATORI, SHIGEKI SAKURABA, MASANORI KASHIWAGI, JUNYA KURIBAYASHI, MIKI TSUJITA, YUKI HOSOKAWA, JUNZO TAKEDA, SHUN-ICHI KUWANA
Publikováno v: Biological Research, Vol 39, Iss 2, Pp 321-330 (2006)
Nicotine exposure is a risk factor in several breathing disorders Nicotinic acetylcholine receptors (nAChRs) exist in the ventrolateral medulla, an important site for respiratory control. We examined the effects of nicotinic acetylcholine neurotransm
Externí odkaz: https://doaj.org/article/0533664b6ae5454cb4651cbeddd29308
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5
Genome-Wide Association Study Identifies Genetic Polymorphisms Associated with Estimated Minimum Effective Concentration of Fentanyl in Patients Undergoing Laparoscopic-Assisted Colectomy
Autor: Daisuke Nishizawa, Tsutomu Mieda, Miki Tsujita, Hideyuki Nakagawa, Shigeki Yamaguchi, Shinya Kasai, Junko Hasegawa, Kyoko Nakayama, Yuko Ebata, Akira Kitamura, Hirotomo Shimizu, Tadayuki Takashima, Masakazu Hayashida, Kazutaka Ikeda
Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8421
Sensitivity to opioids varies widely among individuals. To identify potential candidate single-nucleotide polymorphisms (SNPs) that may significantly contribute to individual differences in the minimum effective concentration (MEC) of an opioid, fent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efdb59a9ed62b73203c953630acaf9c6
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