Zobrazeno 1 - 10
of 96
pro vyhledávání: '"MIKELL PAIGE"'
Autor:
Bryan M. Delfing, Xavier E. Laracuente, Xingyu Luo, Audrey Olson, William Jeffries, Kenneth W. Foreman, Mikell Paige, Kylene Kehn-Hall, Christopher Lockhart, Dmitri K. Klimov
Publikováno v:
ACS Omega, Vol 9, Iss 38, Pp 40259-40268 (2024)
Externí odkaz:
https://doaj.org/article/fa808101ebc248e1b00e2437d38b4502
Autor:
Greg Petruncio, Zachary Shellnutt, Lauren L. Young, Michael Girgis, Wendy K. Strangman, R. Thomas Williamson, Kylene Kehn-Hall, Mikell Paige
Publikováno v:
ACS Omega, Vol 9, Iss 28, Pp 30993-30997 (2024)
Externí odkaz:
https://doaj.org/article/accb0649445a4006be85232d7b57c277
Autor:
Ali Andalibi, Remi Veneziano, Mikell Paige, Michael Buschmann, Amanda Haymond, Virginia Espina, Alessandra Luchini, Lance Liotta, Barney Bishop, Monique Van Hoek
Publikováno v:
SLAS Discovery, Vol 28, Iss 6, Pp 270-274 (2023)
With over 39,000 students, and research expenditures in excess of $200 million, George Mason University (GMU) is the largest R1 (Carnegie Classification of very high research activity) university in Virginia. Mason scientists have been involved in th
Externí odkaz:
https://doaj.org/article/af3387cf6ee045f89afd859e9b7f42f1
Autor:
Kyung Hyeon Lee, Nadia Fazal Ali, Soo Hyeon Lee, Zhimin Zhang, Marie Burdick, Zachary J. Beaulac, Greg Petruncio, Linxia Li, Jiangdong Xiang, Ezra M. Chung, Kenneth W. Foreman, Schroeder M. Noble, Yun M. Shim, Mikell Paige
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The aminopeptidase activity (AP) of the leukotriene A4 hydrolase (LTA4H) enzyme has emerged as a therapeutic target to modulate host immunity. Initial reports focused on the benefits of augmenting the LTA4H AP activity and clearing its putat
Externí odkaz:
https://doaj.org/article/5e035599853c418c91141324ae6d3acc
Autor:
Manuel J. Carrasco, Suman Alishetty, Mohamad-Gabriel Alameh, Hooda Said, Lacey Wright, Mikell Paige, Ousamah Soliman, Drew Weissman, Thomas E. Cleveland, Alexander Grishaev, Michael D. Buschmann
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Carrasco et al. report a method that can predict the lipid nanoparticles (LNP) pKa from the structure of the ionizable lipid. They investigate the delivery efficiency for intramuscular and intravascular administration and propose design principles to
Externí odkaz:
https://doaj.org/article/bbdbf3686db74c9385304e3b47673ec7
Autor:
Ramya Chandrasekaran, Colleen Mathieu, Rishi Sheth, Alexandre P. Cheng, David Fong, Robert McCormack, Hani El-Gabalawy, Suman Alishetty, Mikell Paige, Caroline D. Hoemann
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
UDP-glucose dehydrogenase (UGDH) generates essential precursors of hyaluronic acid (HA) synthesis, however mechanisms regulating its activity are unclear. We used enzyme histostaining and quantitative image analysis to test whether cytokines that sti
Externí odkaz:
https://doaj.org/article/dedddb3ec2f44be299aa315e0cf588fc
Autor:
Angela Dailing, Kelsey Mitchell, Ngoc Vuong, Kyung Hyeon Lee, Reva Joshi, Virginia Espina, Amanda Haymond Still, Carter J. Gottschalk, Anne M. Brown, Mikell Paige, Lance A. Liotta, Alessandra Luchini
Publikováno v:
Frontiers in Chemistry, Vol 8 (2021)
Osteoarthritis (OA) is the most common form of arthritis and the fastest growing cause of chronic disability in the world. Formation of the ternary IL-1β /IL-1R1/IL-1RAcP protein complex and its downstream signaling has been implicated in osteoarthr
Externí odkaz:
https://doaj.org/article/1334db1fa1654443b0c419d36bc615ae
Publikováno v:
Engineering Reports, Vol 2, Iss 3, Pp n/a-n/a (2020)
Abstract It is well known that the mixing of two or more species in flows at low Reynolds numbers cannot be easily achieved since inertial effects are essentially absent and molecular diffusion is slow. To achieve mixing in Newtonian fluids under the
Externí odkaz:
https://doaj.org/article/c66e0bef262d443d8e545d4728bd2987
Autor:
Michael D. Buschmann, Manuel J. Carrasco, Suman Alishetty, Mikell Paige, Mohamad Gabriel Alameh, Drew Weissman
Publikováno v:
Vaccines, Vol 9, Iss 1, p 65 (2021)
The recent success of mRNA vaccines in SARS-CoV-2 clinical trials is in part due to the development of lipid nanoparticle delivery systems that not only efficiently express the mRNA-encoded immunogen after intramuscular injection, but also play roles
Externí odkaz:
https://doaj.org/article/7520c01c5127460eac7a71be1bad4007
Autor:
Bryan M. Delfing, Audrey Olson, Xavier E. Laracuente, Kenneth W. Foreman, Mikell Paige, Kylene Kehn-Hall, Christopher Lockhart, Dmitri K. Klimov
Publikováno v:
The Journal of Physical Chemistry B. 127:3175-3186
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74b3b6e1c32d42c54fb17d4e24c024b4
https://doi.org/10.1021/acs.jpcb.3c00429
https://doi.org/10.1021/acs.jpcb.3c00429