Zobrazeno 1 - 10
of 21
pro vyhledávání: '"MIHO KAKUTA"'
Development of metachronous rectal cancers in a young man with dyskeratosis congenita: a case report
Autor:
Motoko Watanabe, Gou Yamamoto, Kenji Fujiyoshi, Yoshito Akagi, Miho Kakuta, Yoji Nishimura, Kiwamu Akagi
Publikováno v:
Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-6 (2019)
Abstract Background DKC1 (dyskerin pseudouridine synthase 1) is a causative gene for X-linked dyskeratosis congenita. Approximately 8% of patients with dyskeratosis congenita have malignancy, but information about the development of malignancy in pat
Externí odkaz:
https://doaj.org/article/277239f8be094e2e8e3801db4c2d6060
Autor:
GOU YAMAMOTO, TETSUYA ITO, OKIHIDE SUZUKI, NAO KAMAE, MIHO KAKUTA, AKEMI TAKAHASHI, KATSUYA IUCHI, TOMIO ARAI, HIDEYUKI ISHIDA, KIWAMU AKAGI
Publikováno v:
Oncology Letters; Nov2023, Vol. 26 Issue 5, p1-9, 9p
Autor:
Emmanouil Pikoulis, Anastasia Pikouli, Georgios Antonios Margonis, Katsunori Imai, Neda Amini, Shigenori Kadowaki, Jaeyun Wang, Carsten Kamphues, Maria Theochari, Takahiko Akiyama, Despoina Geka, Jan N. M. IJzermans, Miho Kakuta, George Theodoropoulos, Toshiro Ogura, Nikolaos Andreatos, Efstathios Antoniou, Yuki Sakamoto, Nobuya Daitoku, Stefan Buettner, Kiwamu Akagi, Martin E. Kreis, Inge van den Berg
Publikováno v:
Journal of Surgical Oncology, 123(4), 1005-1014. Wiley-Liss Inc.
Background: Although the prognostic relevance of KRAS status in metastatic colorectal cancer (CRC) depends on tumor laterality, this relationship is largely unknown in non-metastatic CRC. Methods: Patients who underwent resection for non-metastatic C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e87bef520b26702d696d86704e5136
https://doi.org/10.1002/jso.26352
https://doi.org/10.1002/jso.26352
Autor:
Miho Kakuta, Keisuke Tanaka, Gou Yamamoto, Izumi Miyabe, Kiwamu Akagi, Motoko Watanabe, Satoru Kawakami, Hideyuki Ishida
Publikováno v:
Eur J Hum Genet
Lynch syndrome is an autosomal dominant hereditary cancer syndrome in which many cancers develop, the main one being colorectal cancer. Germline pathogenic variants in one of four mismatch repair (MMR) genes are known to be causative of this disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc940099bce532a7fc25617ed0dfbe5b
https://doi.org/10.1038/s41431-020-00779-5
https://doi.org/10.1038/s41431-020-00779-5
Autor:
Akemi Takahashi, Tetsuhiko Tachikawa, Shigeki Yamaguchi, Miho Kakuta, Kiwamu Akagi, Gou Yamamoto, Yukiko Osanai, Takanori Washio, Masato Kamiyama, Michio Shiibashi, Takashi Takenoya
Publikováno v:
Familial cancer. 20(2)
Microsatellite instability (MSI) is an effective biomarker for diagnosing Lynch syndrome (LS) and predicting the responsiveness of cancer therapy. MSI testing is conventionally performed by capillary electrophoresis, and MSI status is judged by visua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a777b2a4d41da64376f3ffd99a6172
https://pubmed.ncbi.nlm.nih.gov/32949329
https://pubmed.ncbi.nlm.nih.gov/32949329
Autor:
Hiroshi Sakai, Hiroyasu Kinoshita, Yoshihito Iijima, Kiwamu Akagi, Tomokazu Wakatsuki, Yuki Yamane, Mari Kikuchi, Hirohiko Akiyama, Yoshiko Arai, Yoshito Akagi, Miho Kakuta, Junko Sudo, Futoshi Kurimoto, Shiho Kobayashi, Hideaki Mizutani, Yuki Nakajima, Gou Yamamoto, Kenji Fujiyoshi, Hidetaka Uramoto
Publikováno v:
International Journal of Oncology
After the development of EGFR tyrosine kinase inhibitors (TKIs), genetic testing of EGFR became required for effective treatment of lung cancer. Initially, the testing was conducted separately for each mutated region. However, many EGFR mutations hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecea7fe975eb934ce86eca0cec2ce74f
https://doi.org/10.3892/ijo.2017.3935
https://doi.org/10.3892/ijo.2017.3935
Autor:
Akemi Takahashi, Yoji Nishimura, Kensei Yamaguchi, Miho Kakuta, Yoshito Akagi, Yoshiko Arai, Mina Yamada, Hirohiko Sakamoto, Kiwamu Akagi, Gou Yamamoto, Kenji Fujiyoshi
Publikováno v:
Oncology Reports. 37:785-792
Genetic testing is needed for the treatment of colorectal cancer (CRC), especially molecular-targeted therapy. The effects of anti-EGFR therapy and prognosis are affected by the presence of KRAS mutations. However, whether primary CRC or metastatic t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c04e85c063c8bcd89203b4960088ef8
https://doi.org/10.3892/or.2016.5323
https://doi.org/10.3892/or.2016.5323
Development of metachronous rectal cancers in a young man with dyskeratosis congenita: a case report
Autor:
Gou Yamamoto, Kenji Fujiyoshi, Yoji Nishimura, Yoshito Akagi, Kiwamu Akagi, Motoko Watanabe, Miho Kakuta
Publikováno v:
Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-6 (2019)
Background DKC1 (dyskerin pseudouridine synthase 1) is a causative gene for X-linked dyskeratosis congenita. Approximately 8% of patients with dyskeratosis congenita have malignancy, but information about the development of malignancy in patients wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11dd1837de256e1b84d009f71b101ad2
https://pubmed.ncbi.nlm.nih.gov/31027506
https://pubmed.ncbi.nlm.nih.gov/31027506
Autor:
Shinichiro Horiguchi, Yoshiko Arai, Soichiro Natsume, Sachiko Ohde, Kenji Fujiyoshi, Shinsuke Kazama, Akemi Takahashi, Mina Yamada, Kiwamu Akagi, Miho Kakuta, Yoji Nishimura, Yusuke Nishizawa, Yoshito Akagi, Hirohiko Sakamoto, Misato Takao, Tatsuro Yamaguchi, Gou Yamamoto
Publikováno v:
Cancer Medicine
Microsatellite instability (MSI) is an important biomarker for screening for Lynch syndrome, and also of response to immune checkpoint inhibitors. The aim of this study is to create a predictive model to determine which elderly patients with colorect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8143f09b2b47cadb0ac97c5e12f8c1
https://pubmed.ncbi.nlm.nih.gov/28544821
https://pubmed.ncbi.nlm.nih.gov/28544821
Autor:
Miho Kakuta, Masako Asayama, Akira Ooki, Kiwamu Akagi, Kensei Yamaguchi, Akemi Takahashi, Toshimasa Yatsuoka, Yoji Nishimura, Hiroki Hara
Publikováno v:
Journal of Surgical Oncology. 110:982-988
Background The clinical relevance of combined microsatellite instability (MSI) and BRAF status for adjuvant treatment in stage III colorectal cancer (CRC) remains elusive. Methods In 405 patients with curatively resected stage III CRC, the prognostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ffbb907050d6f18119bbb334f28b0a7
https://doi.org/10.1002/jso.23755
https://doi.org/10.1002/jso.23755