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Akademický článek

The Munich MIDY Pig Biobank – A unique resource for studying organ crosstalk in diabetes

Autor: Andreas Blutke, Simone Renner, Florian Flenkenthaler, Mattias Backman, Serena Haesner, Elisabeth Kemter, Erik Ländström, Christina Braun-Reichhart, Barbara Albl, Elisabeth Streckel, Birgit Rathkolb, Cornelia Prehn, Alessandra Palladini, Michal Grzybek, Stefan Krebs, Stefan Bauersachs, Andrea Bähr, Andreas Brühschwein, Cornelia A. Deeg, Erica De Monte, Michaela Dmochewitz, Caroline Eberle, Daniela Emrich, Robert Fux, Frauke Groth, Sophie Gumbert, Antonia Heitmann, Arne Hinrichs, Barbara Keßler, Mayuko Kurome, Miriam Leipig-Rudolph, Kaspar Matiasek, Hazal Öztürk, Christiane Otzdorff, Myriam Reichenbach, Horst Dieter Reichenbach, Alexandra Rieger, Birte Rieseberg, Marco Rosati, Manuel Nicolas Saucedo, Anna Schleicher, Marlon R. Schneider, Kilian Simmet, Judith Steinmetz, Nicole Übel, Patrizia Zehetmaier, Andreas Jung, Jerzy Adamski, Ünal Coskun, Martin Hrabě de Angelis, Christian Simmet, Mathias Ritzmann, Andrea Meyer-Lindenberg, Helmut Blum, Georg J. Arnold, Thomas Fröhlich, Rüdiger Wanke, Eckhard Wolf

Publikováno v: Molecular Metabolism, Vol 6, Iss 8, Pp 931-940 (2017)

Objective: The prevalence of diabetes mellitus and associated complications is steadily increasing. As a resource for studying systemic consequences of chronic insulin insufficiency and hyperglycemia, we established a comprehensive biobank of long-te

Externí odkaz: https://doaj.org/article/6df6a6d42ef44752b7265a8b82fbcbb7

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Akademický článek

De los números de Midy a la primalidad

Autor: John H. Castillo, Gilberto García-Pulgarín, Juan Miguel Velásquez-Soto

Publikováno v: Revista Integración, Vol 33, Iss 1, Pp 1-10 (2015)

Utilizando propiedades de los números de Midy se define el concepto de q-seudoprimo base b, el cual extiende la idea de seudoprimo fuerte base b, y a partir de dicho concepto se establece un nuevo criterio de primalidad que refina el Teorema de P

Externí odkaz: https://doaj.org/article/afcd0be775f44254812ab2f8674899c1

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Misfolded proinsulin impairs processing of precursor of insulin receptor and insulin signaling in β cells

Autor: Xiaoxi Xu, Ming Liu, Ruimin Zhu, Zhenqian Fan, Jing Yang, Xin Li, Jinhong Sun, Shiqun Liu, Wenli Feng, Jingqiu Cui

Publikováno v: The FASEB Journal

Insulin resistance in classic insulin-responsive tissues is a hallmark of type 2 diabetes (T2D). However, the pathologic significance of β-cell insulin resistance and the underlying mechanisms contributing to defective insulin signaling in β cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e3ae84131b9cff618165353273315a
https://doi.org/10.1096/fj.201900442r

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Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus

Publikováno v: Molecular Metabolism
Mol. Metab. 26, 30-44 (2019)
Molecular Metabolism, Vol 26, Iss, Pp 30-44 (2019)

Objective The liver regulates the availability of insulin to other tissues and is the first line insulin response organ physiologically exposed to higher insulin concentrations than the periphery. Basal insulin during fasting inhibits hepatic glucone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7e5c3953bcd2186340c014cd2aff9c
http://europepmc.org/articles/PMC6667734

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De los números de Midy a la primalidad

Autor: Gilberto García-Pulgarín, John H. Castillo, Juan Miguel Velásquez-Soto

Publikováno v: Revista Integración, Vol 33, Iss 1, Pp 1-10 (2015)
Revista Integración, Vol 33, Iss 1 (2015)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c846d62fd3d8f128c29d4a7c5086524
http://revistas.uis.edu.co/index.php/revistaintegracion/article/view/4765/4924

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The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes

Autor: Sophie Gumbert, C. Otzdorff, Stefan Bauersachs, Jerzy Adamski, Barbara Albl, Marco Rosati, Alessandra Palladini, Eckhard Wolf, Andreas Jung, Kaspar Matiasek, Mattias Backman, Birte Rieseberg, Arne Hinrichs, Mathias Ritzmann, Miriam Leipig-Rudolph, Kilian Simmet, Caroline Eberle, Manuel Nicolas Saucedo, Stefan Krebs, Simone Renner, Robert Fux, Alexandra Rieger, Elisabeth Streckel, Serena Haesner, Christina Braun-Reichhart, Judith Steinmetz, Birgit Rathkolb, Christian Simmet, Ünal Coskun, Cornelia Prehn, Andreas Brühschwein, Erica De Monte, Helmut Blum, Nicole Übel, Martin Hrabě de Angelis, Andreas Blutke, Hazal Öztürk, Andrea Bähr, Frauke Groth, Florian Flenkenthaler, Elisabeth Kemter, Rüdiger Wanke, Thomas Fröhlich, Daniela Emrich, Michal Grzybek, Anna Schleicher, Cornelia A. Deeg, Michaela Dmochewitz, Mayuko Kurome, Andrea Meyer-Lindenberg, H.-D. Reichenbach, Georg J. Arnold, Antonia Heitmann, Patrizia Zehetmaier, M. Reichenbach, Marlon R. Schneider, Erik Ländström, Barbara Keßler

Publikováno v: Molecular Metabolism
Mol. Metab. 6, 931-940 (2017)
Molecular Metabolism, 6 (8)
Molecular Metabolism, Vol 6, Iss 8, Pp 931-940 (2017)

Objective The prevalence of diabetes mellitus and associated complications is steadily increasing. As a resource for studying systemic consequences of chronic insulin insufficiency and hyperglycemia, we established a comprehensive biobank of long-ter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b1481c9a2871b73b2f44f0fbd847be