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pro vyhledávání: '"MICU2"'
Akademický článek
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Autor:
Jack G. Allen, Jeffery S. Tessem
Publikováno v:
Cells, Vol 11, Iss 13, p 1993 (2022)
The Mitochondrial Calcium Uniporter Complex (MCU Complex) is essential for β-cell function due to its role in sustaining insulin secretion. The MCU complex regulates mitochondrial Ca2+ influx, which is necessary for increased ATP production followin
Externí odkaz:
https://doaj.org/article/f3a917619bf54224a9db2b31aae3846f
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT The mitochondrial Ca2+ uptake in trypanosomatids, which belong to the eukaryotic supergroup Excavata, shares biochemical characteristics with that of animals, which, together with fungi, belong to the supergroup Opisthokonta. However, the co
Externí odkaz:
https://doaj.org/article/1059df07d325479ea8ba3200b5c7c3e2
Publikováno v:
Biology Open, Vol 5, Iss 7, Pp 962-969 (2016)
MICU2 has been reported to interact with MICU1 and participate in the regulation of mitochondrial Ca2+ uptake, although the molecular determinants underlying the function of MICU2 is unknown. In order to characterize MICU2 we screened a series of N-t
Externí odkaz:
https://doaj.org/article/27aaa4a21d71426a95b4218d6f3d6cb4
Publikováno v:
Biomedicines, Vol 8, Iss 11, p 451 (2020)
Several studies have indicated the biological role of mitochondrial Ca2+ uptake in cancer pathophysiology; however, its implications in predicting the prognosis of hepatocellular carcinoma (HCC) are not yet fully understood. Here, we collected tumor
Externí odkaz:
https://doaj.org/article/c1ac934563c545f08f530fb38f0a1de3
Autor:
Syed Islamuddin Shah, Ghanim Ullah
Publikováno v:
Cells, Vol 9, Iss 6, p 1520 (2020)
Mitochondrial Ca2+ ([Ca2+]M) uptake through its Ca2+ uniporter (MCU) is central to many cell functions such as bioenergetics, spatiotemporal organization of Ca2+ signals, and apoptosis. MCU activity is regulated by several intrinsic proteins includin
Externí odkaz:
https://doaj.org/article/5a58d0512a7342eda7e7b8ed9738f631
Akademický článek
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Akademický článek
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Autor:
Melanie Paillard, Kai-Ting Huang, David Weaver, Jonathan P. Lambert, John W. Elrod, György Hajnóczky
Publikováno v:
Cell Calcium
Cell Calcium, 2022, 105, pp.102618. ⟨10.1016/j.ceca.2022.102618⟩
Cell Calcium, 2022, 105, pp.102618. ⟨10.1016/j.ceca.2022.102618⟩
International audience; Heart failure (HF) is a leading cause of hospitalization and mortality worldwide. Yet, there is still limited knowledge on the underlying molecular mechanisms, because human tissue for research is scarce, and data obtained in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329bd7055e5473ee680ac28425393931
https://doi.org/10.1016/j.ceca.2022.102618
https://doi.org/10.1016/j.ceca.2022.102618
Publikováno v:
Biomedicines, Vol 8, Iss 451, p 451 (2020)
Biomedicines
Volume 8
Issue 11
Biomedicines
Volume 8
Issue 11
Several studies have indicated the biological role of mitochondrial Ca2+ uptake in cancer pathophysiology
however, its implications in predicting the prognosis of hepatocellular carcinoma (HCC) are not yet fully understood. Here, we collected tu
however, its implications in predicting the prognosis of hepatocellular carcinoma (HCC) are not yet fully understood. Here, we collected tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbaae57792244fbdd4a6ac7e0d82007f
https://www.mdpi.com/2227-9059/8/11/451
https://www.mdpi.com/2227-9059/8/11/451