Zobrazeno 1 - 10
of 282
pro vyhledávání: '"MICROGLIAL CELL ACTIVATION"'
Publikováno v:
Guoji Yanke Zazhi, Vol 18, Iss 8, Pp 1403-1406 (2018)
Tauroursodeoxycholic acid(TUDCA)is formed by taurine conjugated of ursodeoxycholic acid(UDCA). It has the role of neurotrophic factor in anti-inflammatory, anti-apoptosis and reducing the activation of microglial cells. These effects may be one of th
Externí odkaz:
https://doaj.org/article/875ca0c3273345048d002c2f5c5e4c02
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Microglial cells in the central nervous system (CNS) are crucial in maintaining a healthy environment for neurons to function properly. However, aberrant microglial cell activation can lead to excessive generation of neurotoxic proinflammatory mediat
Externí odkaz:
https://doaj.org/article/11d736fa40cc488d99203929b7be2f3f
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Age-associated decline in retina function is largely responsible for the irreversible vision deterioration in the elderly population. It is also an important risk factor for the development of degenerative and angiogenic diseases. However, the molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2ae9810a66d58772116a12b7eae2d1
https://doi.org/10.1155/2021/6715758
https://doi.org/10.1155/2021/6715758
Publikováno v:
Fundamental & Clinical Pharmacology. 36:277-285
Background Damage to the peripheral or central nervous system results in Neuropathic pain. Based on a complicated mechanism, neuropathic pain has no efficient treatment so far. It has been well-known that the expression of some proteins (BDNF, KCC2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925aa5f405d4f151244523d47a782f1d
https://doi.org/10.1111/fcp.12719
https://doi.org/10.1111/fcp.12719
Autor:
Renjuan Sun, Long Tai Zheng, Youliang Ke, Rong Zhang, Xuechu Zhen, Xiaohu Zhang, Zhirou Xu, Junjie Cheng, Huicui Yang
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-18 (2021)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Microglial activation-mediated neuroinflammation plays an important role in the progression of neurodegenerative diseases. Inflammatory activation of microglial cells is often accompanied by a metabolic switch from oxidative phosphorylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505434db7063b9b96b997e9994ecd8ed
https://doaj.org/article/6d3d4d626b494c44b73c826e8b0ecd7b
https://doaj.org/article/6d3d4d626b494c44b73c826e8b0ecd7b
Publikováno v:
Journal of Neuroscience Research
Journal of Neuroscience Research, 2021, 99 (7), pp.1835-1849. ⟨10.1002/jnr.24836⟩
Journal of Neuroscience Research, 2021, 99 (7), pp.1835-1849. ⟨10.1002/jnr.24836⟩
Spinal cord injury (SCI) is a debilitating condition, which leads to a permanent loss of functions below the injury site. The events which take place after SCI are characterized by cellular death, release of inhibitory factors, and inflammation. Many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42cac74cbcc0beb52b062714a7e73c8d
https://doi.org/10.1002/jnr.24836
https://doi.org/10.1002/jnr.24836
Publikováno v:
Aging (Albany NY)
Adaptor molecule downstream of kinase-3 (DOK3) is a vital regulator of innate immune responses in macrophages and B cells, and G-protein-coupled receptor 84 (GPR84) is significant in mediating the biosynthesis and maintenance of inflammatory mediator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4377e5395d87bef67dc20fe322241a2
https://doi.org/10.18632/aging.202144
https://doi.org/10.18632/aging.202144
Autor:
Cheng-Feng Qin, Qing-Feng Wu, Yisheng Jiang, Cui Li, Jing Li, Yafei Chang, Qin Wang, Feng Zhang, Zhiheng Xu
Publikováno v:
Genomics, Proteomics & Bioinformatics
The association of Zika virus (ZIKV) infection with microcephaly has raised alarm worldwide. Their causal link has been confirmed in different animal models infected by ZIKV. However, the molecular mechanisms underlying ZIKV pathogenesis are far from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3944a5efd03faa90f60290894a860fb
https://doi.org/10.1016/j.gpb.2019.06.004
https://doi.org/10.1016/j.gpb.2019.06.004
Autor:
María Carmen Bartolomé-Camacho, Luz Torner, Rosalio Mercado-Camargo, Héctor Eduardo Martínez-Flores, Rosa Elena Pérez-Sánchez, Ana Elisa Toscano, Raul Manhães de Castro, Omar Guzmán-Quevedo, Mercedes Victoria Urquiza-Martínez
Publikováno v:
Journal of Food and Nutrition Research. 8:473-483
Opuntia ficus-indica consumption improves obesity and glucose and lipid metabolism, to name a few; however, the involved mechanism is poorly understood and attributed primarily to fiber. Obesity was recently shown to increase microglial cell activati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bb1d58a9bf006acb6794506bbdddd77
https://doi.org/10.12691/jfnr-8-9-4
https://doi.org/10.12691/jfnr-8-9-4
Autor:
Flavio Tardin, Felipe Dal-Pizzol, Allan Collodel, Tatiana Barichello, Jaqueline S. Generoso, Gursimrat Bhatti, Diogo Dominguini, Cristiano Julio Faller, Fabricia Petronilho, Vijayasree V. Giridharan
Publikováno v:
Neurotherapeutics
Pneumococcal meningitis is a life-threatening infection of the central nervous system (CNS), and half of the survivors of meningitis suffer from neurological sequelae. We hypothesized that pneumococcal meningitis causes CNS inflammation via the disru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0582ac6a0d43852e12b69cca82d179
https://doi.org/10.1007/s13311-020-00917-3
https://doi.org/10.1007/s13311-020-00917-3