Zobrazeno 1 - 10
of 108
pro vyhledávání: '"MICKEY S. URDEA"'
Autor:
Michael Mckenna, Sarah Hamren, Mickey S. Urdea, Theodore M. Tarasow, Anil Patwardhan, Laura Penny
Publikováno v:
Bioanalysis. 3:2233-2251
Complex diseases are caused by combinatorial genetic, environmental and lifestyle factors. The emergence of multibiomarker tests to define these diseases and to identify the early, presymptomatic stages offers several advantages to the conventional u
Autor:
Mickey S. Urdea, Janice A. Kolberg, Elizabeth C. Breen, Peter J. Dailey, John L. Fahey, Jesus F. Salazar-Gonzalez, Wei W. Cao, Pat Sheridan, Lu-Ping Shen
Publikováno v:
Journal of Immunological Methods. 215:123-134
Changes in the patterns of cytokine expression are thought to be of central importance in human infectious and inflammatory diseases. As such, there is a need for precise, reproducible assays for quantification of cytokine mRNA that are amenable to r
Autor:
John M. Leonard, Chris Gee, Hongmei Mo, Mickey S. Urdea, Martin Markowitz, John E. Mittler, Daniel W. Norbeck, P. Scott Eastman, Janice A. Kolberg, Eric Boyer, Reed Kelso
Publikováno v:
Journal of Virology. 72:5154-5164
Ten subjects received 600 to 1,200 mg of the human immunodeficiency virus type 1 (HIV-1) protease inhibitor ritonavir per day. Following 2 weeks of therapy, plasma HIV RNA levels decreased by a mean of 1.57 (range, 0.89 to 1.96) log units. With conti
Publikováno v:
Nucleic Acids Research. 25:4842-4849
The divergent synthesis of bDNA structures is described. This new type of branched DNA contains one unique oligonucleotide, the primary sequence, covalently attached through a comb-like branching network to many identical copies of a different oligon
Publikováno v:
Nucleic Acids Research. 25:4835-4841
The divergent synthesis of branched DNA (bDNA) comb structures is described. This new type of bDNA contains one unique oligonucleotide, the primary sequence, covalently attached through a comb-like branch network to many identical copies of a differe
Publikováno v:
Clinical Chemistry. 43:1507-1511
Cloning of the hepatitis C virus (HCV) genome was a tremendous advance in the development of tests for diagnosis and monitoring of HCV-infected patients. Serological tests, including enzyme-linked immunoassays and RIBATM strip immunoblot assays, are
Autor:
Gary L. Davis, Etsuro Orito, Janice A. Kolberg, Johnson Y.N. Lau, Mickey S. Urdea, Masashi Mizokami, Jill Detmer, Mark L. Collins, Ke-Ping Qian
Publikováno v:
The Journal of Infectious Diseases. 176:421-426
GB virus C/hepatitis G virus (GBV-C/HGV) is a newly described virus associated with hepatitis in humans, and GBV-C/HGV coinfection is common in patients chronically infected with hepatitis C virus (HCV). To determine the clinical impact of GBV-C/HGV
Autor:
Jungsuh P. Kim, Mickey S. Urdea, Janice A. Kolberg, George G. Schlauder, Bhavna Bhardwaj, Masashi Mizokami, Gary L. Davis, Ke-Ping Qian, Johnson Y.N. Lau, Jeffrey M. Linnen, Jill Detmer
Publikováno v:
Journal of Medical Virology. 52:92-96
Three PCR methods based on the GB virus-C/hepatitis G virus (GBV-C/HGV) 5′UTR and NS3 genomic region were used for the detection of GBV-C/HBV RNA in serum of 62 patients with chronic hepatitis C virus (HCV) infection. Ten of 62 (16%) patients were
Autor:
Michael S. German, Janice A. Kolberg, Mickey S. Urdea, Franz M. Matschinsky, Juehu Wang, Lu-Ping Shen, Habiba Najafi
Publikováno v:
Proceedings of the National Academy of Sciences. 94:4360-4365
Glucose tightly regulates the synthesis and secretion of insulin by beta cells in the pancreatic islets of Langerhans. To investigate whether glucose regulates insulin synthesis at the level of insulin RNA splicing, we developed a method to detect an
Autor:
Judith C. Wilber, Mickey S. Urdea, Norah A. Terrault, Bhupinder N. Bhandari, Mark L. Collins, Peter J. Dailey, Teresa L. Wright, Linda D. Ferrell
Publikováno v:
Journal of Medical Virology. 51:217-224
The optimal method for viral quantitation and the most appropriate site for determining viral load in patients with chronic hepatitis C virus (HCV) infection are unknown. We developed a method for measuring HCV RNA in the liver with the following fea