Zobrazeno 1 - 10
of 89
pro vyhledávání: '"MICHITAKA, SHICHIJO"'
Autor:
Michitaka Shichijo, Shinichi Kondo, Mina Ishimori, Shinichi Watanabe, Heidi Helin, Tsugiko Yamasaki, Mary E Stevens, Florian Gantner, Kevin B Bacon
Publikováno v:
Allergology International, Vol 55, Iss 3, Pp 271-278 (2006)
Background: To investigate the functional role of protease activated receptor (PAR) -2 in T lymphocytes, we analyzed TCR-mediated inflammatory cytokine production using PAR-2 deficient (KO) and wild type (WT) mice. Methods: Production of serum IgE an
Externí odkaz:
https://doaj.org/article/39843e3c18dd46c38ca10ccc9dfbf58e
Autor:
Toshinobu Kato, Masahiro Kimata, Toshikazu Tsuji, Michitaka Shichijo, Masayuki Murata, Toru Miura, Isao Serizawa, Naoki Inagaki, Hiroichi Nagai
Publikováno v:
Allergology International, Vol 51, Iss 3, Pp 197-203 (2002)
Background: Although β-adrenergic receptor agonists inhibit antigen-induced release of histamine, leukotrienes and prostaglandin D2 from human lung fragments, dispersed human lung mast cells and human skin mast cells, subcellular mechanisms for the
Externí odkaz:
https://doaj.org/article/785d8520e9ce48ae9f3049dbb2c30022
Autor:
Mami Oikawa, Tomoe Nishimura, Michitaka Shichijo, Narumi Ogonuki, Satoshi Kamimura, Kimiko Inoue, Takachika Hiroi, Kazufumi Katayama, Soichi Tofukuji, Akio Mori, Mayumi Saeki, Yusuke Shimo, Atsuo Ogura, Satoru Ishida, Osamu Kaminuma, Noriko Kitamura, Shigeki Katoh
Publikováno v:
EMBO reports. 18:885-893
T-cell receptor (TCR)-transgenic mice have been employed for evaluating antigen-response mechanisms, but their non-endogenous TCR might induce immune response differently than the physiologically expressed TCR Nuclear transfer cloning produces animal
Autor:
Yasuhiko Tomita, Naoki Inagaki, Hiroyuki Tanaka, Miwa Aoki, Yoji Nagira, Michitaka Shichijo, Shingo Furue, Kumiko Goto
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 357:273-280
Prostaglandin D2(PGD2) is involved in the pathogenesis of allergic rhinitis. However, the sensory nervous system-mediated contributions of PGD2to the symptoms of allergic rhinitis remain unclear. We investigated the involvement of PGD2in these sympto
Autor:
Michitaka Shichijo, Azumi Ueyama, Masaya Shimizu, Kazufumi Katayama, Takayuki Okuno, Yoshikazu Sasaki, Chihiro Imura, Kenichiro Tsujii, Yoko Furue, Kiyoshi Yasui, Nobuyuki Tai, Mina Yamamoto
Publikováno v:
Journal of dermatological science. 93(3)
Background Retinoic acid receptor-related orphan receptor gamma t (RORγt) has critical roles in the development, maintenance and function of interleukin (IL)-17-producing cells and is a highly attractive target for the treatment of IL-17-mediated au
Autor:
Akira Kugimiya, Fujio Asanuma, William M. Abraham, Go Takahashi, Shingo Sakamoto, Goro Kuwajima, Masashi Deguchi, Michitaka Shichijo, Maki Hattori, Akinori Arimura, Yasuhiko Tomita, Noriko Suzuki
Publikováno v:
European Journal of Pharmacology. 765:15-23
Prostaglandin (PG) D2 elicits responses through either the DP1 and/or DP2 receptor. Experimental evidence suggests that stimulation of the DP1 receptor contributes to allergic responses, such that antagonists are considered to be directed therapies f
Autor:
Ken ichi Nezasa, Eugene P. Frenkel, Toru Wada, Satomi Shinonome, Keiji Dohi, Kanji Hojo, Michitaka Shichijo, Koichi Masuno, T. Yamada, Motofumi Iguchi, Norihito Sato, Hidekazu Tanaka, Tatsuya Sugimoto, Shuji Yonezawa, Yukichi Ishioka, Kenji Matsuo, Makiko Inoue, Michinari Hirata
Publikováno v:
Cancer Science
Epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) are validated molecular targets in cancer therapy. Dual blockade has been explored and one such agent, lapatinib, is in clinical practice but with modest acti
Autor:
Michitaka, Shichijo 1, Yasuo, Shimizu 2, Kenju, Hiramatsu 2, Michinori, Togawa 1, Naoki, Inagaki 1, Kenzo, Takagi 2, Hiroichi, Nagai 1, *
Publikováno v:
In Japanese Journal of Pharmacology 1999 79(4):501-504
Autor:
Itsuki Oshima, Yasuyuki Fusamae, Michitaka Shichijo, Kenichiro Tsujii, Mina Yamamoto, Kiyoshi Yasui, Miwa Aoki, Minoru Suzuki, Azumi Ueyama, Chihiro Imura, Yoko Furue, Tomohiko Okuda
Publikováno v:
Journal of dermatological science. 85(1)
Background Psoriasis is one of the most common immune-mediated chronic inflammatory skin disorders and is accompanied by erythematous scaly plaques. There is growing evidence that the IL-23/Th17 axis plays a critical role in development of the diseas
Autor:
Minoru Ikeda, Naoko Higuchi, Michitaka Shichijo, Naoki Inagaki, Go Takahashi, Hiroyuki Tanaka
Publikováno v:
International Archives of Allergy and Immunology. 158:359-368
Background: Allergic rhinitis is the most common allergic disease, displaying the typical nasal symptom of congestion. Prostaglandin D2 (PGD2), a chemical mediator released in large amounts by mast cells upon allergic stimulation in humans, is known