Zobrazeno 1 - 10
of 262
pro vyhledávání: '"MICHEL WASSEF"'
Autor:
Pierre Romero, Laia Richart, Setareh Aflaki, Ambre Petitalot, Megan Burton, Audrey Michaud, Julien Masliah-Planchon, Frédérique Kuhnowski, Samuel Le Cam, Carlos Baliñas-Gavira, Céline Méaudre, Armelle Luscan, Abderaouf Hamza, Patricia Legoix, Anne Vincent-Salomon, Michel Wassef, Daniel Holoch, Raphaël Margueron
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Mutations in chromatin regulators are widespread in cancer. Among them, the histone H3 lysine 27 methyltransferase Polycomb Repressive Complex 2 (PRC2) shows distinct alterations according to tumor type. This specificity is poorly understood
Externí odkaz:
https://doaj.org/article/1b39f7921f8b45b382015dc3a19b069d
Autor:
David Rombaut, Carine Lefèvre, Tony Rached, Sabrina Bondu, Anne Letessier, Raphael M. Mangione, Batoul Farhat, Auriane Lesieur-Pasquier, Daisy Castillo-Guzman, Ismael Boussaid, Chloé Friedrich, Aurore Tourville, Magali De Carvalho, Françoise Levavasseur, Marjorie Leduc, Morgane Le Gall, Sarah Battault, Marie Temple, Alexandre Houy, Didier Bouscary, Lise Willems, Sophie Park, Sophie Raynaud, Thomas Cluzeau, Emmanuelle Clappier, Pierre Fenaux, Lionel Adès, Raphael Margueron, Michel Wassef, Samar Alsafadi, Nicolas Chapuis, Olivier Kosmider, Eric Solary, Angelos Constantinou, Marc-Henri Stern, Nathalie Droin, Benoit Palancade, Benoit Miotto, Frédéric Chédin, Michaela Fontenay
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Myelodysplastic syndromes (MDS) with mutated SF3B1 gene present features including a favourable outcome distinct from MDS with mutations in other splicing factor genes SRSF2 or U2AF1. Molecular bases of these divergences are poorly understoo
Externí odkaz:
https://doaj.org/article/123566d884df484c9b7e6a5d549470f7
Autor:
Arnault Tauziède-Espariat, Thibaut Pierre, Michel Wassef, David Castel, Florence Riant, Jacques Grill, Alexandre Roux, Johan Pallud, Edouard Dezamis, Damien Bresson, Sandro Benichi, Thomas Blauwblomme, Djallel Benzohra, Guillaume Gauchotte, Celso Pouget, Sophie Colnat-Coulbois, Karima Mokhtari, Corinne Balleyguier, Frédérique Larousserie, Volodia Dangouloff-Ros, Nathalie Boddaert, Marie-Anne Debily, Lauren Hasty, Marc Polivka, Homa Adle-Biassette, Alice Métais, Emmanuèle Lechapt, Fabrice Chrétien, Felix Sahm, Philipp Sievers, Pascale Varlet, the RENOCLIP-LOC
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-11 (2022)
Abstract The International Society for the Study of Vascular Anomalies (ISSVA) has defined four vascular lesions in the central nervous system (CNS): arteriovenous malformations, cavernous angiomas (also known as cerebral cavernous malformations), ve
Externí odkaz:
https://doaj.org/article/ea31d1f1e8ef422d8660512d17fda86d
Autor:
Jordan Orly, Annouk Bisdorff, Aline Joly, Afi-Emiliène Edee, Elsa Tavernier, Denis Herbreteau, Olivia Boccara, Michel Wassef, Annabel Maruani
Publikováno v:
Acta Dermato-Venereologica, Vol 103 (2023)
Intramuscular capillary-type haemangiomas (ICTH) are rare vascular anomalies that can easily be misdiagnosed as other entities. A systematic review was performed of all cases of ICTH in the literature since its first description in 1972. An adjudicat
Externí odkaz:
https://doaj.org/article/1e65a30ebad14eb5a2eaf61ae70980cd
Autor:
Florentina Pascale, Jean-Pierre Pelage, Michel Wassef, Saïda H. Ghegediban, Jean-Pierre Saint-Maurice, Thierry De Baere, Alban Denys, Rafael Duran, Frédéric Deschamps, Olivier Pellerin, Noboru Maeda, Alexandre Laurent, Julien Namur
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The rabbit VX2 is a large animal model of cancer used for decades by interventional radiologists to demonstrate the efficacy of various locoregional treatments against liver tumors. What do we know about this tumor in the new era of targeted therapy
Externí odkaz:
https://doaj.org/article/e6fc9cf69aa4461394a6c2fd4f473dee
Autor:
Antoine Campagne, Ming-Kang Lee, Dina Zielinski, Audrey Michaud, Stéphanie Le Corre, Florent Dingli, Hong Chen, Lara Z. Shahidian, Ivaylo Vassilev, Nicolas Servant, Damarys Loew, Eric Pasmant, Sophie Postel-Vinay, Michel Wassef, Raphaël Margueron
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
In Drosophila, the Calypso–ASX complex catalyzes H2A deubiquitination and aids Polycomb in transcriptional silencing. Here the authors show that the orthologous complex, BAP1.com, promotes gene activation by counteracting PRC1-mediated gene silenci
Externí odkaz:
https://doaj.org/article/92338fdb37b04b3b97a5b2deb5e4d404
Autor:
Yan Wang, Haizhen Long, Juan Yu, Liping Dong, Michel Wassef, Baowen Zhuo, Xia Li, Jicheng Zhao, Min Wang, Cuifang Liu, Zengqi Wen, Luyuan Chang, Ping Chen, Qian-fei Wang, Xueqing Xu, Raphael Margueron, Guohong Li
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-18 (2018)
Abstract Background The hierarchical organization of eukaryotic chromatin plays a central role in gene regulation, by controlling the extent to which the transcription machinery can access DNA. The histone variants H3.3 and H2A.Z have recently been i
Externí odkaz:
https://doaj.org/article/9bcdce8575f142c6ade14220a178e71e
Autor:
Samar Alsafadi, Alexandre Houy, Aude Battistella, Tatiana Popova, Michel Wassef, Emilie Henry, Franck Tirode, Angelos Constantinou, Sophie Piperno-Neumann, Sergio Roman-Roman, Martin Dutertre, Marc-Henri Stern
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Mutations in the splicing factor SF3B1 are found in uveal melanoma. Here, Alsafadi et al. use RNA-sequencing data from these cancers and experimental models, and show that mutant SF3B1 promotes alternative branchpoints in a specific gene subset and t
Externí odkaz:
https://doaj.org/article/895eb1555d734fbe947b98b9284ba24c
Autor:
Marion Classe, Hui Yao, Roger Mouawad, Chad J. Creighton, Alice Burgess, Frederick Allanic, Michel Wassef, Xavier Leroy, Benjamin Verillaud, Geoffrey Mortuaire, Franck Bielle, Christophe Le Tourneau, Jean-Emmanuel Kurtz, David Khayat, Xiaoping Su, Gabriel G. Malouf
Publikováno v:
Cell Reports, Vol 25, Iss 3, Pp 811-821.e5 (2018)
Summary: Esthesioneuroblastoma (ENB) is a rare cancer of the olfactory mucosa, with no established molecular stratification to date. We report similarities of ENB with tumors arising in the neural crest and perform integrative analysis of these tumor
Externí odkaz:
https://doaj.org/article/4d98bc81390c4d639fbf7c5b3c275f94
Autor:
Florentina Pascale, Afshin Fazel, Julien Namur, Saida-Homayra Ghegediban, Hadrian D’Inca, Michel Wassef, Laurence Moine, Alexandre Laurent
Publikováno v:
Tumor Biology, Vol 39 (2017)
The purpose of our study was to assess the effect of controlled-release chemotherapy on the growth and viability of peritoneal carcinomatosis treated by subperitoneal injection in a rabbit VX2 model. A model of peritoneal carcinomatosis was created b
Externí odkaz:
https://doaj.org/article/08fec4330e5e46359dbf7c0cd08f805a