Zobrazeno 1 - 10
of 20
pro vyhledávání: '"MICHEL CHRETIEN"'
Autor:
SIMON BISSONNETTE, VALÉRIE LAMANTIA, YANNICK CYR, MARIE DEVAUX, RÉMI RABASA-LHORET, MICHEL CHRETIEN, MAYA SALEH, MAY FARAJ
Publikováno v:
Diabetes. 71
Background and Hypothesis: Elevated plasma apoB-lipoproteins (hyperapoB, mostly LDL) predicts the incidence of type 2 diabetes (T2D) and its risk factors including systemic activation of the interleukin-1 system (measured as plasma IL-1 receptor anta
Autor:
Annie V. Roy, Michael Chan, Logan Banadyga, Shihua He, Wenjun Zhu, Michel Chrétien, Majambu Mbikay
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Background Several in silico studies have determined that quercetin, a plant flavonol, could bind with strong affinity and low free energy to SARS-CoV-2 proteins involved in viral entry and replication, suggesting it could block infection of
Externí odkaz:
https://doaj.org/article/60a83caae5604ed2ad00ce4881acec4a
Autor:
Simon Bissonnette, Valérie Lamantia, Benjamin Ouimet, Yannick Cyr, Marie Devaux, Remi Rabasa-Lhoret, Michel Chrétien, Maya Saleh, May Faraj
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Elevated plasma numbers of atherogenic apoB-lipoproteins (apoB), mostly as low-density lipoproteins (LDL), predict diabetes risk by unclear mechanisms. Upregulation of the NLRP3 inflammasome/interleukin-1 beta (IL-1β) system in white adipos
Externí odkaz:
https://doaj.org/article/0a83e95703d94c1093fe7679d3611bd4
Autor:
Majambu Mbikay, Michel Chrétien
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Isoquercetin and quercetin are secondary metabolites found in a variety of plants, including edible ones. Isoquercetin is a monoglycosylated derivative of quercetin. When ingested, isoquercetin accumulates more than quercetin in the intestinal mucosa
Externí odkaz:
https://doaj.org/article/a7eea6a5d6dc4b738b98687a4944d5f7
Publikováno v:
Scopus-Elsevier
There is growing appreciation that the nucleus is organized into an array of discrete structural domains, each subserving a specific function. These functional nuclear bodies are to be distinguished from pathological intranuclear inclusions which hav
Autor:
Ajoy Basak, Peter Koch, Marcel Dupelle, Francine Sirois, Michel Chretien, Nabil G. Seidah, Majambu Mbikay
Publikováno v:
ChemInform. 34
Autor:
Rudolf Peierls, Michel Chretien
The paper investigates the possibility of introducing 'non-local' interactions, i.e. interactions represented by four-dimensional integral operations, in order to eliminate divergences in the quantum theory of interacting fields. In particular, a typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35bf74253fe6c84d90ebe5416f7f897a
https://doi.org/10.1142/9789812795779_0042
https://doi.org/10.1142/9789812795779_0042
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-3 (2020)
Abstract Soluble low-density lipoprotein receptor (sLDLR) is the circulating ectodomain of transmembrane LDLR. Its blood level strongly correlates with that of triglycerides (TG). This correlation has eluded satisfactory explanation. Hypertriglycerid
Externí odkaz:
https://doaj.org/article/cd66b719ffe84769ad38e48174334e5c
Autor:
Yannick Cyr, Valérie Lamantia, Simon Bissonnette, Melanie Burnette, Aurèle Besse‐Patin, Annie Demers, Martin Wabitsch, Michel Chrétien, Gaétan Mayer, Jennifer L. Estall, Maya Saleh, May Faraj
Publikováno v:
Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)
Abstract Background LDL‐cholesterol lowering variants that upregulate receptor uptake of LDL, such as in PCSK9 and HMGCR, are associated with diabetes via unclear mechanisms. Activation of the NLRP3 inflammasome/interleukin‐1 beta (IL‐1β) path
Externí odkaz:
https://doaj.org/article/55e8b3a5fa1f4be4a5bf58b8cf9bb904
Autor:
Olesya Fedoryak, Charles Arama, Issa Diarra, Bouréma Kouriba, Michel Chrétien, Majambu Mbikay
Publikováno v:
Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 2020 (2020)
Recent evidence suggests that proprotein convertase subtilisin/kexin type 9 (PCSK9), a downmodulator of cellular uptake of blood cholesterol, also negatively impacts host immune response to microbial infection. In this study, we investigated whether
Externí odkaz:
https://doaj.org/article/06126bf1ac6e4c48abff9868fc0424b9