Zobrazeno 1 - 10
of 208
pro vyhledávání: '"MICHAEL R. RICKELS"'
Autor:
Saba Sheikh, Darko Stefanovski, Marissa J. Kilberg, Denis Hadjiliadis, Ronald C. Rubenstein, Michael R. Rickels, Andrea Kelly
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Insulin secretion within 30 minutes of nutrient ingestion is reduced in people with cystic fibrosis (PwCF) and pancreatic insufficiency and declines with worsening glucose tolerance. The glucose potentiated arginine (GPA) test is validated for quanti
Externí odkaz:
https://doaj.org/article/9eeb2aa56d794eaba42d9d8a793761d6
Autor:
Bibi Uhre Nielsen, Inger Hee Mabuza Mathiesen, Rikke Møller, Rikke Krogh-Madsen, Terese Lea Katzenstein, Tacjana Pressler, James A. M. Shaw, Christian Ritz, Michael R. Rickels, Darko Stefanovski, Thomas Peter Almdal, Daniel Faurholt-Jepsen
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
AimsThe purpose of the study was to further elucidate the pathophysiology of cystic fibrosis (CF)-related diabetes (CFRD) and potential drivers of hypoglycaemia. Hence, we aimed to describe and compare beta cell function (insulin and proinsulin) and
Externí odkaz:
https://doaj.org/article/88132567683d426abc643eb60765c95a
Autor:
Arnaud D. Kaze, Matthew F. Yuyun, Rexford S. Ahima, Michael R. Rickels, Justin B. Echouffo-Tcheugui
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
There are limited data on the link between cardiac autonomic neuropathy (CAN) and severe hypoglycemia in type 2 diabetes. Here, we evaluated the associations of CAN with severe hypoglycemia among 7,421 adults with type 2 diabetes from the Action to C
Externí odkaz:
https://doaj.org/article/e6a7fc5d379a4599bc58d2ada86b42d6
Autor:
Susan Kohl Malone, Amy J. Peleckis, Laura Grunin, Gary Yu, Sooyong Jang, James Weimer, Insup Lee, Michael R. Rickels, Namni Goel
Publikováno v:
Journal of Diabetes Research, Vol 2021 (2021)
Nocturnal hypoglycemia is life threatening for individuals with type 1 diabetes (T1D) due to loss of hypoglycemia symptom recognition (hypoglycemia unawareness) and impaired glucose counter regulation. These individuals also show disturbed sleep, whi
Externí odkaz:
https://doaj.org/article/64477c20e8a4441f8a998b9f62479412
Autor:
Scott A. Soleimanpour M.D., Boaz Hirshberg, David J. Bunnell, Anne E. Sumner, Marilyn Ader, Alan T. Remaley, Kristina I. Rother, Michael R. Rickels, David M. Harlan
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Although islet transplantation may restore insulin independence to individuals with type 1 diabetes mellitus, most have abnormal glucose tolerance. We asked whether the defective glucose tolerance is due to inadequate β-cell mass or to impaired insu
Externí odkaz:
https://doaj.org/article/88fe3f10357d496bb82aee1eaf134f26
Autor:
Bashoo Naziruddin Ph.D., Steve Wease, Donald Stablein, Franca B. Barton, Thierry Berney, Michael R. Rickels, Rodolfo Alejandro
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Pancreatic islet transplantation is a promising treatment option for patients severely affected with type 1 diabetes. This report from CITR presents pre- and posttransplant human leukocyte antigen (HLA) class I sensitization rates in islet-alone tran
Externí odkaz:
https://doaj.org/article/e5e6af115275405fa49d13b740e27eff
Autor:
Melissa S. Putman, Andrew W. Norris, Rebecca L. Hull, Michael R. Rickels, Lori Sussel, Scott M. Blackman, Christine L. Chan, Katie Larson Ode, Tanicia Daley, Arlene A. Stecenko, Antoinette Moran, Meagan J. Helmick, Sharon Cray, Jessica A. Alvarez, Virginia A. Stallings, Katherine L. Tuggle, John P. Clancy, Thomas L. Eggerman, John F. Engelhardt, Andrea Kelly
Publikováno v:
Diabetes. 72:677-689
Cystic fibrosis (CF) is a recessive disorder arising from mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR is expressed in numerous tissues, with high expression in the airways, small and lar
Autor:
Anneliese J. Flatt, Amy J. Peleckis, Cornelia Dalton-Bakes, Huong-Lan Nguyen, Sarah Ilany, Austin Matus, Susan K. Malone, Namni Goel, Sooyong Jang, James Weimer, Insup Lee, Michael R. Rickels
Publikováno v:
Diabetes Technology & Therapeutics. 25:302-314
Autor:
Anneliese J. Flatt, Elizabeth Chen, Amy J. Peleckis, Cornelia Dalton-Bakes, Huong-Lan Nguyen, Heather W. Collins, John S. Millar, Robert J. Gallop, Michael R. Rickels
Publikováno v:
Diabetes technologytherapeutics. 24(10)
Repeated hypoglycemia exposure leads to impaired awareness of hypoglycemia (IAH) and the development of defective counterregulatory responses. To date, only pancreas or islet transplantation has demonstrated normalization of hypoglycemia awareness an
Autor:
Michael R, Rickels, Thomas L, Eggerman, Levent, Bayman, Julie C, Qidwai, Rodolfo, Alejandro, Nancy D, Bridges, Bernhard J, Hering, James F, Markmann, Peter A, Senior, Lawrence G, Hunsicker, Irene, Feurer
Publikováno v:
Diabetes Care. 45:2967-2975
OBJECTIVE To determine long-term outcomes for islet-alone and islet-after-kidney transplantation in adults with type 1 diabetes complicated by impaired awareness of hypoglycemia. RESEARCH DESIGN AND METHODS This was a prospective interventional and o