Zobrazeno 1 - 10
of 124
pro vyhledávání: '"MICHAEL F. LEAHY"'
Autor:
Ruben A. Mesa, Stacie Hudgens, Lysbeth Floden, Claire N. Harrison, Jeanne Palmer, Vikas Gupta, Donal P. McLornan, Mary F. McMullin, Jean‐Jaques Kiladjian, Lynda Foltz, Uwe Platzbecker, M. Laura Fox, Adam J. Mead, David M. Ross, Stephen T. Oh, Andrew Perkins, Michael F. Leahy, Samineh Deheshi, Rafe Donahue, Barbara J. Klencke, Srdan Verstovsek
Publikováno v:
Cancer Medicine, Vol 12, Iss 9, Pp 10612-10624 (2023)
Abstract Background Myelofibrosis (MF)‐associated constitutional symptoms can severely impact health‐related quality of life. Clinical trials in MF traditionally measure symptom response to treatment as a landmark endpoint of total symptom score
Externí odkaz:
https://doaj.org/article/e6eb999637b34b008d60fd675f19d445
Autor:
Ruben A. Mesa, Claire Harrison, Jeanne M. Palmer, Vikas Gupta, Donal P. McLornan, Mary Frances McMullin, Jean-Jacques Kiladjian, Lynda Foltz, Uwe Platzbecker, Maria Laura Fox, Adam J. Mead, David M. Ross, Stephen T. Oh, Andrew Charles Perkins, Michael F. Leahy, Jun Kawashima, Sunhee Ro, Rafe Donahue, Boris Gorsh, Samineh Deheshi, Srdan Verstovsek
Publikováno v:
HemaSphere, Vol 7, Iss 11, p e966 (2023)
Myelofibrosis (MF) is a chronic myeloproliferative neoplasm that typically manifests with debilitating symptoms that progressively worsen, negatively impacting patients’ quality of life. Fatigue is a multifactorial and burdensome MF-related symptom
Externí odkaz:
https://doaj.org/article/f9632edb1b7c4fa09e09d3f5fe8a8134
Autor:
Kevin M. Trentino, Shannon L. Farmer, Michael F. Leahy, Frank M. Sanfilippo, James P. Isbister, Rhonda Mayberry, Axel Hofmann, Aryeh Shander, Craig French, Kevin Murray
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background There are no overviews of systematic reviews investigating haemoglobin thresholds for transfusion. This is important as the literature on transfusion thresholds has grown considerably in recent years. Our aim was to synthesise evi
Externí odkaz:
https://doaj.org/article/9b77b22f3b844e95972e78d72ca2e64d
Publikováno v:
Clinical Case Reports, Vol 8, Iss 5, Pp 843-847 (2020)
Abstract We report a rare case of aggressive plasmablastic lymphoma with an initial presentation of dermatomyositis. The challenges associated with the diagnosis and treatment approach are also highlighted in this case report.
Externí odkaz:
https://doaj.org/article/561ae6a348d74e07b1dda52cd8d7abe3
Publikováno v:
Case Reports in Hematology, Vol 2020 (2020)
Chronic lymphocytic leukaemia is a slow-growing leukaemia of developing B-lymphocytes, which may transform to an aggressive lymphoma known as Richter’s syndrome. While Richter’s syndrome can present in untreated or relapsed-refractory cases, it m
Externí odkaz:
https://doaj.org/article/53449e97e71f4e4095d8a0989a241e5e
Autor:
Ryan J Collinson, Lynne Wilson, Darren Boey, Zi Yun Ng, Bob Mirzai, Hun S Chuah, Rebecca Howman, Carolyn S Grove, Jacques A J Malherbe, Michael F Leahy, Matthew D Linden, Kathryn A Fuller, Wendy N Erber, Belinda B Guo
Publikováno v:
Platelets, Vol 35, Iss 1 (2024)
Transcription factor 3 (TCF3) is a DNA transcription factor that modulates megakaryocyte development. Although abnormal TCF3 expression has been identified in a range of hematological malignancies, to date, it has not been investigated in myelofibros
Externí odkaz:
https://doaj.org/article/8a8bf5c785ff42dba6fe62c17e84f290
Autor:
Ruben Mesa, Claire Harrison, Jeanne M. Palmer, Vikas Gupta, Donal P. McLornan, Mary Frances McMullin, Jean-Jacques Kiladjian, Lynda Foltz, Uwe Platzbecker, Maria Laura Fox, Adam J Mead, David M Ross, Stephen T Oh, Andrew Charles Perkins, Michael F. Leahy, Jun Kawashima, Sunhee Ro, Rafe Donahue, Samineh Deheshi, Srdan Verstovsek
Publikováno v:
Blood. 140:9677-9680
Autor:
Kevin M. Trentino, Michael F. Leahy, Wendy N. Erber, Hamish Mace, Kylie Symons, Charley A. Budgeon, Kevin Murray
Publikováno v:
Anesthesia & Analgesia. 135:586-591
Autor:
Kylie Symons, Michael F. Leahy, Frank M Sanfilippo, Rory Watts, Kevin Murray, Kevin M Trentino, Jeffrey M. Hamdorf, Hamish Mace, Shannon L Farmer
Publikováno v:
Anesthesia & Analgesia. 132:344-352
BACKGROUND In 2016, a preoperative clinic was implemented to screen, evaluate, and manage anemia and suboptimal iron stores at a major tertiary care medical center in Western Australia. Few studies compare the costs and reimbursements associated with
Autor:
William Reed, Richard Eek, Andrew Nicol, Radha Prathikanti, Rebecca Elstrom, Hannah Rose, Michael F. Leahy, Aileen Cohen, Jingjing Schneider, Xavier Badoux, Constantine S. Tam, Nicholas Wickham, H. Miles Prince, Sushrut Patil, Jane Huang, Hang Quach, Ian W. Flinn
Publikováno v:
Blood Adv
Zanubrutinib (BGB-3111) is a next-generation Bruton tyrosine kinase inhibitor designed to be more selective with fewer off-target effects. We conducted a phase 1 study to assess the safety of its combination with obinutuzumab and evaluate early effic