Zobrazeno 1 - 10
of 866
pro vyhledávání: '"MICHAEL A. HENRY"'
Publikováno v:
Cell Reports, Vol 16, Iss 10, Pp 2686-2698 (2016)
Opioids remain the standard for analgesic care; however, adverse effects of systemic treatments contraindicate long-term administration. While most clinical opioids target mu opioid receptors (MOR), those that target the delta class (DOR) also demons
Externí odkaz:
https://doaj.org/article/69b6dfbb4b994fe0a7a7f55e19607177
Publikováno v:
PAIN Reports, Vol 3, Iss 3, p e658 (2018)
Abstract. Introduction:. Chronic metabotropic glutamate receptor activation in nociceptive afferents may upregulate A-Kinase Anchoring Protein 150 (AKAP150) expression and/or function. Objectives:. To quantify transcriptional changes in AKAP150 expre
Externí odkaz:
https://doaj.org/article/fbb132ac7b5b471b999934c246b72b11
Autor:
Morgan C. Finnerty, Franklin E. Leach, Yousef Zakharia, Kenneth G. Nepple, Michael G. Bartlett, Michael D. Henry, Brian S. Cummings
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Docetaxel is commonly used for treatment of castration-resistant prostate cancer. Unfortunately, many prostate cancer patients develop resistance to docetaxel. Clinical markers less invasive than biopsies, such as blood samples, would be ide
Externí odkaz:
https://doaj.org/article/e6ae2ad0ea39429b927acce33bffe893
Autor:
Michael B. Henry, Emily Funsten, Marisa A. Michealson, Danielle Albright, Cameron S. Crandall, David P. Sklar, Naomi George, Margaret Greenwood-Ericksen
Publikováno v:
Western Journal of Emergency Medicine, Vol 25, Iss 5, Pp 758-766 (2024)
Introduction: The United States lacks a national interfacility patient transfer coordination system. During the coronavirus 2019 (COVID-19) pandemic, many hospitals were overwhelmed and faced difficulties transferring sick patients, leading some stat
Externí odkaz:
https://doaj.org/article/b517c813593c4bcc9307cf2f952c4517
Autor:
Mary E. Herndon, Mitchell Ayers, Katherine N. Gibson-Corley, Michael K. Wendt, Lori L. Wallrath, Michael D. Henry, Christopher S. Stipp
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 9 (2024)
Externí odkaz:
https://doaj.org/article/1e678e4757f2403b873c0fa0b35faf2b
Autor:
Jean Muragizi, Mindi Guptill, Bogdan G. Dumitriu, Michael B. Henry, Adam R. Aluisio, Jean Paul Nzabandora, Appolinaire Manirafasha, Janette Baird, Katelyn Morretti, Naz Karim
Publikováno v:
African Journal of Emergency Medicine, Vol 13, Iss 3, Pp 147-151 (2023)
Introduction: While trends in analgesia have been identified in high-income countries, little research exists regarding analgesia administration in low- and middle-income countries (LMIC). This study evaluates analgesia administration and clinical ch
Externí odkaz:
https://doaj.org/article/d36eb7e0fb044fa485c22e8a723570c2
Autor:
Jianling Bi, Emily Witt, Megan K. McGovern, Arielle B. Cafi, Lauren L. Rosenstock, Anna B. Pearson, Timothy J. Brown, Thomas B. Karasic, Lucas C. Absler, Srija Machkanti, Hannah Boyce, David Gallo, Sarah L. Becker, Keiko Ishida, Joshua Jenkins, Alison Hayward, Alexandra Scheiflinger, Kellie L. Bodeker, Ritesh Kumar, Scott K. Shaw, Salma K. Jabbour, Vitor A. Lira, Michael D. Henry, Michael S. Tift, Leo E. Otterbein, Giovanni Traverso, James D. Byrne
Publikováno v:
Advanced Science, Vol 11, Iss 9, Pp n/a-n/a (2024)
Abstract Modulation of autophagy, specifically its inhibition, stands to transform the capacity to effectively treat a broad range of cancers. However, the clinical efficacy of autophagy inhibitors has been inconsistent. To delineate clinical and epi
Externí odkaz:
https://doaj.org/article/f858b9587aa7486a8b205a415ae94226
Autor:
Bernard Nsengiyumva, Michael B. Henry, Heather M. Kuntz, Molly K. Estes, Melanie M. Randall, Mindi Guptill
Publikováno v:
African Journal of Emergency Medicine, Vol 12, Iss 4, Pp 428-431 (2022)
Introduction: Chest trauma is a major contributor to injury morbidity and mortality, and understanding trends is a crucial part of addressing this burden in low- and middle-income countries. This study reports the characteristics and emergency depart
Externí odkaz:
https://doaj.org/article/1b0681561e064fa686c85d61e62d58d1
Autor:
Marion Vanneste, Anita Venzke, Soumitra Guin, Andrew J. Fuller, Andrew J. Jezewski, Sarah R. Beattie, Damian J. Krysan, Marvin J. Meyers, Michael D. Henry
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionAn attractive, yet unrealized, goal in cancer therapy is repurposing psychiatric drugs that can readily penetrate the blood-brain barrier for the treatment of primary brain tumors and brain metastases. Phenothiazines (PTZs) have demonstra
Externí odkaz:
https://doaj.org/article/4334b357eab940c8a068c9537ffc9a99
Autor:
Melissa A. Marchal, Devon L. Moose, Afshin Varzavand, Nicole E. Jordan, Destiney Taylor, Munir R. Tanas, James A. Brown, Michael D. Henry, Christopher S. Stipp
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionAbl family kinases function as proto-oncogenes in various leukemias, and pro-tumor functions have been discovered for Abl kinases in many solid tumors as well. However, a growing body of evidence indicates that Abl kinases can function to
Externí odkaz:
https://doaj.org/article/3f74f3b22e7d4202910ff27fb642931d