Zobrazeno 1 - 10
of 475
pro vyhledávání: '"MICHAEL A. BRODSKY"'
Autor:
Prashant D. Tailor, MD, Timothy T. Xu, MD, Blake H. Fortes, MD, Raymond Iezzi, MD, Timothy W. Olsen, MD, Matthew R. Starr, MD, Sophie J. Bakri, MD, Brittni A. Scruggs, MD, PhD, Andrew J. Barkmeier, MD, Sanjay V. Patel, MD, Keith H. Baratz, MD, Ashlie A. Bernhisel, MD, Lilly H. Wagner, MD, Andrea A. Tooley, MD, Gavin W. Roddy, MD, PhD, Arthur J. Sit, MD, Kristi Y. Wu, MD, Erick D. Bothun, MD, Sasha A. Mansukhani, MBBS, Brian G. Mohney, MD, John J. Chen, MD, PhD, Michael C. Brodsky, MD, Deena A. Tajfirouz, MD, Kevin D. Chodnicki, MD, Wendy M. Smith, MD, Lauren A. Dalvin, MD
Publikováno v:
Mayo Clinic Proceedings: Digital Health, Vol 2, Iss 1, Pp 119-128 (2024)
Objective: To determine the appropriateness of ophthalmology recommendations from an online chat-based artificial intelligence model to ophthalmology questions. Patients and Methods: Cross-sectional qualitative study from April 1, 2023, to April 30,
Externí odkaz:
https://doaj.org/article/b989e4cca22a42128f8a8334faf81ad8
Autor:
Katharina E. Meijboom, Abbas Abdallah, Nicholas P. Fordham, Hiroko Nagase, Tomás Rodriguez, Carolyn Kraus, Tania F. Gendron, Gopinath Krishnan, Rustam Esanov, Nadja S. Andrade, Matthew J. Rybin, Melina Ramic, Zachary D. Stephens, Alireza Edraki, Meghan T. Blackwood, Aydan Kahriman, Nils Henninger, Jean-Pierre A. Kocher, Michael Benatar, Michael H. Brodsky, Leonard Petrucelli, Fen-Biao Gao, Erik J. Sontheimer, Robert H. Brown, Zane Zeier, Christian Mueller
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
A hexanucleotide repeat expansion in C9ORF72 is the most common genetic cause of ALS and FTD. Here, the authors demonstrate CRISPR/Cas9 excision of the expansion results in a rescue of disease mechanisms in vivo and in vitro.
Externí odkaz:
https://doaj.org/article/3c12d94acb99423da250fefe20d4cde2
Autor:
Michael C. Brodsky, Rory J. Olson, Faizal Z. Asumda, Madeline Q.R. Lopour, Lisa A. Schimmenti, Eric W. Klee
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 30, Iss , Pp 101825- (2023)
Purpose: To highlight the importance of the utility of clinical exome sequencing, and show how it led to the diagnosis of nonsyndromic autosomal dominant optic atrophy arising from an autosomal dominant variant in AFG3L2. Observations: A healthy fath
Externí odkaz:
https://doaj.org/article/51567a3b645d46b79f683f7b6a11a12f
Autor:
Madeline Q.R. Lopour, Lisa A. Schimmenti, Nicole J. Boczek, Hutton M. Kearney, Arlene V. Drack, Michael C. Brodsky
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 29, Iss , Pp 101745- (2023)
Purpose: To describe a case of Alström syndrome arising from maternal uniparental disomy. Observations: A 13-month-old boy with poor vision and nystagmus was diagnosed with Alström syndrome based on genetic testing that identified a homozygous path
Externí odkaz:
https://doaj.org/article/b128732b228c4ff098da2573bce87b65
Autor:
Michael C. Brodsky, Arlene Drack
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 25, Iss , Pp 101307- (2022)
Purpose: To illustrate the potential diagnostic confusion between Batten disease and Stargardt disease created by associated signs and symptoms. Observations: A six-year-old girl with vision loss and prominent behavioral changes and overlooking was p
Externí odkaz:
https://doaj.org/article/07f9ceb5645f470c9456ef81f9ef907b
Publikováno v:
Survey of Ophthalmology. 68:556-561
A 14-year-old boy with a history of shunted congenital hydrocephalus began having headaches with nausea and vomiting after transcontinental flights. He gradually developed horizontal diplopia indicative of mild bilateral sixth nerve palsy, without pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1944820a91c4bbf30230ae034ee9420
https://doi.org/10.1016/j.survophthal.2022.02.003
https://doi.org/10.1016/j.survophthal.2022.02.003
Autor:
Michael C. Brodsky, Deborah L. Renaud
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 22, Iss , Pp 101035- (2021)
Purpose: This report describes pseudopapilledema in two siblings with Cockayne syndrome and examines a structural mechanism for its development. Observations: Two siblings with genetically documented Cockayne syndrome, enophthalmos, and hyperopia wer
Externí odkaz:
https://doaj.org/article/b123bda5a91c4e1a99d79d4e626d27db
Autor:
Aamir Mir, Julia F. Alterman, Matthew R. Hassler, Alexandre J. Debacker, Edward Hudgens, Dimas Echeverria, Michael H. Brodsky, Anastasia Khvorova, Jonathan K. Watts, Erik J. Sontheimer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Resistance of gRNA to ubiquitous ribonucleases is required for CRISPR-Cas9-based therapeutics. Here, the authors explore chemical modifications at all positions of the crRNA guide and tracrRNA cofactor, and identify modified versions that are more po
Externí odkaz:
https://doaj.org/article/b945b146d35544ef9d5a4a30d633c3c0
Autor:
VISHAL N. RAO, LISA A. KALTENBACH, BRADI B. GRANGER, GREGG C. FONAROW, HUSSEIN R. AL-KHALIDI, NANCY M. ALBERT, JAVED BUTLER, LARRY A. ALLEN, DAVID E. LANFEAR, DAN ARIELY, JULIE M. MILLER, MICHAEL A. BRODSKY, THOMAS A. LALONDE, JAMES C. LAFFERTY, CHRISTOPHER B. GRANGER, ADRIAN F. HERNANDEZ, ADAM D. DEVORE
Publikováno v:
Journal of Cardiac Failure. 28:1487-1496
It is unknown whether digital applications can improve guideline-directed medical therapy (GDMT) and outcomes in heart failure with reduced ejection fraction (HFrEF).Care Optimization Through Patient and Hospital Engagement Clinical Trial for Heart F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3400d20928a2515c403fd967cb14936f
https://doi.org/10.1016/j.cardfail.2022.07.050
https://doi.org/10.1016/j.cardfail.2022.07.050
Autor:
Stacy L. Pineles, Robert J. Henderson, Michael X. Repka, Gena Heidary, Grant T. Liu, Amy T. Waldman, Mark S. Borchert, Sangeeta Khanna, Jennifer S. Graves, Janine E. Collinge, Julie A. Conley, Patricia L. Davis, Raymond T. Kraker, Susan A. Cotter, Jonathan M. Holmes, Melinda Y. Chang, Dilshad Contractor, Emily J. Zolfaghari, Aarti Vyas, Tiffany Yuen, Veeral S. Shah, Evelyn A. Paysse, Gihan Romany, Jason H. Peragallo, Judy L. Brower, Aparna Raghuram, Bilal Al Wattar, Ryan Chinn, Srishti Kothari, R. Michael Siatkowski, Maria E. Lim, Alisha N. Brewer, Annette M. Doughty, Sonny W. Icks, Shannon Almeida, Alejandra de Alba Campomanes, Premilla Banwait, Leila Hajkazemshirazi, Yizhuo Bastea-Forte, Jennifer K. Arjona, Jeremy Chen, Karen Cooper, Rafif Ghadban, Sophia M. Chung, Oscar A. Cruz, Traci A. Christenson, Lisa L. Breeding, Dawn M. Govreau, Beth A. Wallis, Brooke E. Geddie, Elisabeth T. Wolinski, Indre M. Rudaitis, Jacqueline Twite, Carrie S. Bloomquist, Sarah R. Laboy, Jackie M. Twite, Michelle V. Doan, Marianne J. Bernardo, Michael C. Brodsky, John J. Chen, Suzanne M. Wernimont, Lindsay L. Czaplewski, Stacy L. Eastman, Moriah A. Keehn, Debbie M. Priebe, Don L. Bremer, Richard P. Golden, Catherine O. Jordan, Mary Lou McGregor, Rachel E. Reem, David L. Rogers, Amanda N. Schreckengost, Sara A. Maletic, Mays A. Dairi, Laura B. Enyedi, Sarah K. Jones, Navajyoti R. Barman, Robert J. House, David A. Nasrazadani, Sean M. Gratton, Justin D. Marsh, Rebecca J. Dent, Lezlie L. Bond, Lori L. Soske, Padmaja Sudhakar, Christi M. Willen, Deborah Taylor, Nathaniel Q. Moliterno, Michael Nsoesie, Shaista Vally, Paul H. Phillips, Robert S. Lowery, Beth Colon, Nancy L. Stotts, Kelly D. To, Collin M. McClelland, Raymond G. Areaux, Ann M. Holleschau, Kim S. Merrill, Luis H. Ospina, Rosanne Superstein, Maryse Thibeault, Helene Gagnon, Sean P. Donahue, Scott T. Ruark, Lisa A. Fraine, Petrice A. Sprouse, Ronald J. Biernacki, Robert A. Avery, Brian J. Forbes, Imran Jivraj, Anita A. Kohli, Meg M. Richter, Agnieshka Baumritter, Ellen B. Mitchell, Ken K. Nischal, Lauren M. Runkel, Bianca Blaha, Whitney Churchfield, Christina Fulwylie, Melissa W. Ko, Luis J. Mejico, Muhammad Iqbal, Catherine E. Attanasio, Lena F. Deb, Courtney B. Goodrich, Alisha M. Hartwell, Jennifer A. Moore, Lisa Bohra, Alexandra O. Apkarian, Elena M. Gianfermi, John D. Roarty, Leemor B. Rotberg, Susan N. Perzyk, Roy W. Beck, Darrell S. Austin, Nicole M. Boyle, Danielle L. Chandler, Patricia L. Connelly, Courtney L. Conner, Trevano W. Dean, Quayleen Donahue, Brooke P. Fimbel, Amra Hercinovic, James E. Hoepner, Joseph D. Kaplon, Zhuokai Li, Gillaine Ortiz, Julianne L. Robinson, Kathleen M. Stutz, David O. Toro, Victoria C. Woodard, Rui Wu, Laura Balcer, Mark Kupersmith, Elizabeth L. Lazar, Amy Waldman, David K. Wallace, Eileen E. Birch, Angela M. Chen, Stephen P. Christiansen, S. Ayse Erzurum, Donald F. Everett, Sharon F. Freedman, William V. Good, Katherine A. Lee, Richard London, Vivian M. Manh, Ruth E. Manny, David G. Morrison, Bonita R. Schweinler, Jayne L. Silver, Lisa C. Verderber, Katherine K. Weise, Ari Green, Marie Diener-West, John D. Baker, Barry Davis, Dale L. Phelps, Stephen W. Poff, Richard A. Saunders, Lawrence Tychsen
Publikováno v:
Ophthalmology. 129:856-864
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::078428402105112beb8ec6989190302d
https://doi.org/10.1016/j.ophtha.2022.03.021
https://doi.org/10.1016/j.ophtha.2022.03.021