Zobrazeno 1 - 10
of 417
pro vyhledávání: '"MICB"'
Autor:
Hitoshi Toyoda, Atsuo Kuramasu, Masahiro Hosonuma, Masakazu Murayama, Yoichiro Narikawa, Junya Isobe, Yuta Baba, Kohei Tajima, Eiji Funayama, Midori Shida, Yuki Maruyama, Aya Sasaki, Yuya Hirasawa, Toshiaki Tsurui, Hirotsugu Ariizumi, Tomoyuki Ishiguro, Risako Suzuki, Sei Kobayashi, Atsushi Horiike, Noriko Hida, Takehiko Sambe, Koji Nobe, Satoshi Wada, Hitome Kobayashi, Mayumi Tsuji, Shinichi Kobayashi, Takuya Tsunoda, Yoshifumi Kudo, Yuji Kiuchi, Kiyoshi Yoshimura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Natural killer group 2 member D ligands (NKG2DLs) are expressed as stress response proteins in cancer cells. NKG2DLs induce immune cell activation or tumor escape responses, depending on their expression. Human pancreatic cancer cells, PANC-
Externí odkaz:
https://doaj.org/article/9cc18d13b98e4eae855bec63d4c5642c
Autor:
A. Yu. Stolbovaya, I. V. Smirnov
Publikováno v:
Медицинская иммунология, Vol 25, Iss 3, Pp 483-488 (2023)
MICA and MICB are non-classical MHC molecules that indicate cellular stress. They act as ligands for NKG2D receptors found on NK cells, thereby triggering a cytotoxic response against damaged, infected, or transformed cells. The production of soluble
Externí odkaz:
https://doaj.org/article/fa733b70daea4505a2251de940138998
Autor:
Kerry A. Whalen, Kavya Rakhra, Naveen K. Mehta, Alexander Steinle, Jennifer S. Michaelson, Patrick A. Baeuerle
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTThe field of immuno-oncology has revolutionized cancer patient care and improved survival and quality of life for patients. Much of the focus in the field has been on exploiting the power of the adaptive immune response through therapeutic ta
Externí odkaz:
https://doaj.org/article/fb972df6cd544835ae785a6f2c34f6d4
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundDiabetic nephropathy (DN), which is the main cause of renal failure in end-stage renal disease, is becoming a common chronic renal disease worldwide. Mendelian randomization (MR) is a genetic tool that is widely used to minimize confounding
Externí odkaz:
https://doaj.org/article/fce88db4b6794d7b95ed1d4622705b13
Autor:
Imaniar Noor Faridah, Haafizah Dania, Rita Maliza, Wan-Hsuan Chou, Wen-Hung Wang, Yen-Hsu Chen, Dyah Aryani Perwitasari, Wei-Chiao Chang
Publikováno v:
Diagnostics, Vol 13, Iss 21, p 3365 (2023)
Dengue is an arboviral disease that has spread globally and become a major public health concern. A small proportion of patients may progress from symptomatic dengue fever (DF) to dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). Finding
Externí odkaz:
https://doaj.org/article/d38a883a71ad441494e8ce6b904de3c0
Publikováno v:
Медицинская иммунология, Vol 24, Iss 1, Pp 41-52 (2022)
The MIC genes are located on chromosome 6 in the class I major histocompatibility complex (MHC) region and encode a membrane-bound stress-inducible protein that acts as a ligand to stimulate the NKG2D activating receptor expressed on the surface of t
Externí odkaz:
https://doaj.org/article/f6151638b4d64d22aae08625e5980b0d
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Akademický článek
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Autor:
Alena Machuldova, Monika Holubova, Valentina S. Caputo, Miroslava Cedikova, Pavel Jindra, Lucie Houdova, Pavel Pitule
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural killer cells possess key regulatory function in various malignant diseases, including acute myeloid leukemia. NK cell activity is driven by signals received through ligands binding activating or inhibitory receptors. Their activity towards el
Externí odkaz:
https://doaj.org/article/7f5e4c10b31c466bb224c23b27d3d567
Akademický článek
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