Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma

Autor: MI Rosenberg, E Greenstein, M Buchkovich, M Mikl, A Peres, E Santoni-Rugiu, D Reshef, A Salovin, DL Gibbs, MS Irwin, A Naranjo, I Ulitsky, PA de Alarcon, V Weigman, G Yaari, JA Panzer, N Friedman, JM Maris

SummaryNeuroblastoma is a lethal childhood solid tumor of developing peripheral nerves. Two percent of children with neuroblastoma develop Opsoclonus Myoclonus Ataxia Syndrome (OMAS), a paraneoplastic disease characterized by cerebellar and brainstem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c14aa2a979a20ce12a67a3c7a8280b8f
https://doi.org/10.1101/2021.12.14.471886

Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma.

Autor: Rosenberg MI; Hebrew University of Jerusalem, Edmond Safra Campus, Givat Ram, Jerusalem 91904, Israel. Electronic address: miriamirosenberg@gmail.com., Greenstein E; Department of Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel., Buchkovich M; Q2 Solutions, Durham, NC, USA., Peres A; Bio-engineering, Faculty of Engineering, Bar Ilan University, Ramat Gan, Israel; Bar Ilan Institute of Nanotechnologies and Advanced Materials, Bar Ilan University, Ramat Gan, Israel., Santoni-Rugiu E; Department of Pathology, Rigshospitalet, Copenhagen University Hospital and Department of Clinical Medicine, University of Copenhagen, 2100 Copenhagen, Denmark., Yang L; Pacific Northwest Research Institute, Seattle, WA 98122, USA., Mikl M; Department of Human Biology, Faculty of Natural Sciences, University of Haifa, Mount Carmel, Haifa 31905, Israel., Vaksman Z; New York Genome Center, New York, NY 10013, USA., Gibbs DL; Institute for Systems Biology, 401 Terry Avenue N, Seattle, WA 98109, USA., Reshef D; Department of Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel., Salovin A; Division of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Irwin MS; Department of Pediatrics and Division of Hematology-Oncology, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON M5G1X8, Canada., Naranjo A; Department of Biostatistics, University of Florida, Children's Oncology Group Statistics & Data Center, Gainesville, FL, USA., Ulitsky I; Department of Immunology & Regenerative Biology, Weizmann Institute of Science, Rehovot 7610001, Israel., de Alarcon PA; Department of Pediatrics, Hematology/Oncology, University of Illinois College of Medicine Peoria, Peoria, IL 61605, USA., Matthay KK; Department of Pediatrics, UCSF School of Medicine, San Francisco, CA 94143, USA., Weigman V; Q2 Solutions, Durham, NC, USA., Yaari G; Bio-engineering, Faculty of Engineering, Bar Ilan University, Ramat Gan, Israel; Bar Ilan Institute of Nanotechnologies and Advanced Materials, Bar Ilan University, Ramat Gan, Israel., Panzer JA; Division of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Friedman N; Department of Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel., Maris JM; Department of Pediatrics and Division of Oncology, Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: maris@chop.edu.

Publikováno v: Cell reports [Cell Rep] 2023 Aug 29; Vol. 42 (8), pp. 112879. Date of Electronic Publication: 2023 Aug 02.

The mlpt/Ubr3/Svb module comprises an ancient developmental switch for embryonic patterning.

Autor: Ray S; Department of Biology, Developmental Biology, University of Erlangen-Nuremberg, Erlangen, Germany., Rosenberg MI; Department of Ecology, Evolution and Behavior, Hebrew University of Jerusalem, Jerusalem, Israel., Chanut-Delalande H; Centre de Biologie du Développement, Université Paul Sabatier de Toulouse, Toulouse, France., Decaras A; Institut de Génomique Fonctionelle de Lyon, Lyon, France., Schwertner B; Department of Biology, Developmental Biology, University of Erlangen-Nuremberg, Erlangen, Germany., Toubiana W; Institut de Génomique Fonctionelle de Lyon, Lyon, France., Auman T; Department of Ecology, Evolution and Behavior, Hebrew University of Jerusalem, Jerusalem, Israel., Schnellhammer I; Department of Biology, Developmental Biology, University of Erlangen-Nuremberg, Erlangen, Germany., Teuscher M; Department of Biology, Developmental Biology, University of Erlangen-Nuremberg, Erlangen, Germany., Valenti P; Centre de Biologie du Développement, Université Paul Sabatier de Toulouse, Toulouse, France., Khila A; Institut de Génomique Fonctionelle de Lyon, Lyon, France., Klingler M; Department of Biology, Developmental Biology, University of Erlangen-Nuremberg, Erlangen, Germany., Payre F; Centre de Biologie du Développement, Université Paul Sabatier de Toulouse, Toulouse, France.

Publikováno v: ELife [Elife] 2019 Mar 21; Vol. 8. Date of Electronic Publication: 2019 Mar 21.

Molecular biology. Hiding in plain sight.

Autor: Rosenberg MI; Center for Developmental Genetics, Department of Biology, New York University, New York, NY 10003, USA., Desplan C

Publikováno v: Science (New York, N.Y.) [Science] 2010 Jul 16; Vol. 329 (5989), pp. 284-5.

Heads and tails: evolution of antero-posterior patterning in insects.

Autor: Rosenberg MI; Department of Biology, New York University, New York, NY 10003, USA., Lynch JA, Desplan C

Publikováno v: Biochimica et biophysica acta [Biochim Biophys Acta] 2009 Apr; Vol. 1789 (4), pp. 333-42. Date of Electronic Publication: 2008 Oct 11.