Zobrazeno 1 - 10
of 1 653
pro vyhledávání: '"MHC-II"'
Autor:
Daxi Sun, Liting Yu, Gang Wang, Yuxue Xu, Peng Wang, Ningning Wang, Zhengyan Wu, Guilong Zhang, Jia Zhang, Yunjiao Zhang, Geng Tian, Pengfei Wei
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Chemodynamic therapy represents a novel tumor therapeutic modality via triggering catalytic reactions in tumors to yield highly toxic reactive oxygen species (ROS). Nevertheless, low efficiency catalytic ability, potential systemic toxicity
Externí odkaz:
https://doaj.org/article/7b3abc1028864e0f90b4c09f0bab4360
Autor:
Lorenzo Azzi, Fabrizio Celesti, Anna Maria Chiaravalli, Amruth Kaleem Basha Shaik, Mariam Shallak, Andrea Gatta, Paolo Battaglia, Stefano La Rosa, Angelo Tagliabue, Roberto Sergio Accolla, Greta Forlani
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Oral Squamous Cell Carcinoma (OSCC) is the most common malignant tumor of the oral cavity. Despite recent advances in the field of oral cancer therapy, including the introduction of immunotherapeutic approaches, the 5-year survival rate remains stead
Externí odkaz:
https://doaj.org/article/2e27451192e2498fa97458bdd3b03998
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract The prediction of major histocompatibility complex (MHC)-peptide binding affinity is an important branch in immune bioinformatics, especially helpful in accelerating the design of disease vaccines and immunity therapy. Although deep learning
Externí odkaz:
https://doaj.org/article/b3fbca8fdd14477e957a7171c95215bb
Autor:
Feng Li, Bowen Niu, Lingling Liu, Mengmin Zhu, Hua Yang, Boyin Qin, Xiuhua Peng, Lixiang Chen, Chunhua Xu, Xiaohui Zhou
Publikováno v:
Animal Models and Experimental Medicine, Vol 6, Iss 6, Pp 585-597 (2023)
Abstract Background Staphylococcus aureus can cause serious infections by secreting many superantigen exotoxins in “carrier” or “pathogenic” states. HLA DQ and HLA DR humanized mice have been used as a small animal model to study the role of
Externí odkaz:
https://doaj.org/article/1dbad711446a41028d6483c8d80e176a
Publikováno v:
Frontiers in Oral Health, Vol 5 (2024)
In a murine model (LCΔMHC-II) designed to abolish MHC-II expression in Langerhans cells (LCs), ∼18% of oral LCs retain MHC-II, yet oral mucosal CD4 T cells numbers are unaffected. In LCΔMHC-II mice, we now show that oral intraepithelial conventio
Externí odkaz:
https://doaj.org/article/0ac138362d3f4eb893dfcd4fc8a5dd38
Autor:
Nyerhovwo Obarorakpor, Deep Patel, Reni Boyarov, Nansalmaa Amarsaikhan, Joseph Ray Cepeda, Doreen Eastes, Sylvia Robertson, Travis Johnson, Kai Yang, Qizhi Tang, Li Zhang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/f5c7ff647ef741eb9a8e132f5b2a68df
Publikováno v:
Microorganisms, Vol 12, Iss 7, p 1270 (2024)
Vandammella animalimorsus is a Gram-negative and non-motile bacterium typically transmitted to humans through direct contact with the saliva of infected animals, primarily through biting, scratches, or licks on fractured skin. The absence of a confir
Externí odkaz:
https://doaj.org/article/01251fac5e874256940786951b3a4451
Autor:
Karim Amrane, Coline Le Meur, Benjamin Besse, Patrice Hemon, Pierre Le Noac’h, Olivier Pradier, Christian Berthou, Ronan Abgral, Arnaud Uguen
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Since the advent of anti-PD1 immune checkpoint inhibitor (ICI) immunotherapy, cutaneous melanoma has undergone a true revolution with prolonged survival, as available 5-year updates for progression-free survival and overall survival demonstrate a dur
Externí odkaz:
https://doaj.org/article/79301deafc554a8f867d18463bc077bf
Autor:
M. Violet Lee, Ola M. Saad, Sylvia Wong, Jason LaMar, Lynn Kamen, Ben Ordonia, Rachel Melendez, Azadeh Hassanzadeh, Shan Chung, Surinder Kaur
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Major histocompatibility complex (MHC)-Associated Peptide Proteomics (MAPPs) is an ex vivo method used to assess the immunogenicity risk of biotherapeutics. MAPPs can identify potential T-cell epitopes within the biotherapeutic molecule. Using adalim
Externí odkaz:
https://doaj.org/article/0bd769f29dfe4b1888748f001e7e2a9e
Autor:
Hayley Goodson, Rebeca Kawahara, Sayantani Chatterjee, Gabriel Goncalves, Joshua Fehring, Anthony W. Purcell, Nathan P. Croft, Morten Thaysen-Andersen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Immunopeptidomics, the study of peptide antigens presented on the cell surface by the major histocompatibility complex (MHC), offers insights into how our immune system recognises self/non-self in health and disease. We recently discovered that hyper
Externí odkaz:
https://doaj.org/article/53ee36d9515f4cada11bd942d09ddfa2