Zobrazeno 1 - 10
of 114
pro vyhledávání: '"MHC class I-related"'
Autor:
Sang Eun Yoon, Sujin Park, Junhun Cho, Kyung Ju Ryu, Booma Yandava, Sewon Lee, Seok Jin Kim, Won Seog Kim
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionSoluble MHC class I-related chain A (sMICA) and B (sMICB) play a critical role tumor evolution and poor prognosis through an immune evasion mechanism. Thus, this study determines the interaction between sMICA/sMICB and the tumor immune en
Externí odkaz:
https://doaj.org/article/745c8b0762bd4e0ab1222c844cf50db1
Autor:
Caroline L. Ashley, Brian P. McSharry, Hamish E. G. McWilliam, Richard J. Stanton, Ceri A. Fielding, Rommel A. Mathias, David P. Fairlie, James McCluskey, Jose A. Villadangos, Jamie Rossjohn, Allison Abendroth, Barry Slobedman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe antigen presentation molecule MHC class I related protein-1 (MR1) is best characterized by its ability to present bacterially derived metabolites of vitamin B2 biosynthesis to mucosal-associated invariant T-cells (MAIT cells).MethodsT
Externí odkaz:
https://doaj.org/article/53babfbfbc814e488fc54d15c6f86de6
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/33e8f85ccdb54fb6839a033f11e28822
Autor:
Ayako Kurioka, Aminu S. Jahun, Rachel F. Hannaway, Lucy J. Walker, Joannah R. Fergusson, Eva Sverremark-Ekström, Alexandra J. Corbett, James E. Ussher, Christian B. Willberg, Paul Klenerman
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Human mucosal-associated invariant T (MAIT) cells are an important T cell subset that are enriched in tissues and possess potent effector functions. Typically such cells are marked by their expression of Vα7.2-Jα33/Jα20/Jα12 T cell receptors, and
Externí odkaz:
https://doaj.org/article/d1cf7cfefcfc43e5b6eb34a7536e0ea4
Publikováno v:
Iranian Journal of Immunology, Vol 13, Iss 1, Pp 45-53 (2016)
Background: The role of Matrix Metalloproteinase 9 (MMP9) in tumor invasion and progression is prominent. A single nucleotide polymorphism (SNP) in the promoter region of MMP9 (-1562 C/T) increases the transcription and expression of this gene. On th
Externí odkaz:
https://doaj.org/article/b62586651f3f4c6794439cd779ee9079
Autor:
Samer, Carolyn
The ubiquitously expressed antigen-presenting molecule major histocompatibility complex (MHC) class I-related gene protein (MR1) presents microbial metabolites derived from bacteria and fungi biosynthesis of vitamin B. Recognition of surface MR1-anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______293::07ad4a01f4d8db055773e6b692dc2fc9
https://hdl.handle.net/2123/31361
https://hdl.handle.net/2123/31361
Autor:
Joana Dias, Caroline Boulouis, Michał J. Sobkowiak, Kerri G. Lal, Johanna Emgård, Marcus Buggert, Tiphaine Parrot, Jean-Baptiste Gorin, Edwin Leeansyah, Johan K. Sandberg
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Mucosa-associated invariant T (MAIT) cells are unconventional innate-like T cells that recognize microbial riboflavin metabolites presented by the monomorphic MHC class I-related (MR1) molecule. Despite the high level of evolutionary conservation of
Externí odkaz:
https://doaj.org/article/038617b87e864717a3541f1a2f2e4e2f
Akademický článek
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Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2172-2196 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2172-2196 (2021)
Immunotherapy is a rapidly developing area of cancer treatment due to its higher specificity and potential for greater efficacy than traditional therapies. Immune cell modulation through the administration of drugs, proteins, and cells can enhance an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35de5eede84d436e4c319659616fdaea
http://europepmc.org/articles/PMC8424374
http://europepmc.org/articles/PMC8424374
Akademický článek
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