Zobrazeno 1 - 10
of 350
pro vyhledávání: '"MHC, Major histocompatibility complex"'
Publikováno v:
Cells, Vol 10, Iss 8, p 1955 (2021)
Innate and adaptive immune systems are evolutionarily divergent. Primary signaling in T and B cells depends on somatically rearranged clonotypic receptors. In contrast, NK cells use germline-encoded non-clonotypic receptors such as NCRs, NKG2D, and L
Externí odkaz:
https://doaj.org/article/c600714e9fa74fdea24224c4a3093e1e
Publikováno v:
The Journal of Allergy and Clinical Immunology
Our understanding of risk factors and interventions influencing outcomes from coronavirus disease 2019 (COVID-19) has continued to evolve, revealing advances emerging from hypotheses formed at the start of the pandemic. Epidemiologic studies have sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078357d10622749990a0e5c126f1cecf
https://doi.org/10.1016/j.jaci.2021.12.775
https://doi.org/10.1016/j.jaci.2021.12.775
Autor:
Jia Le Lee, Michelle A. Linterman
Publikováno v:
Immunology Letters
Highlights • Older people are more susceptible to poor health outcomes after infection. • Ageing is associated with reduced antibody titres in response to vaccination, limiting vaccine efficacy. • A key contributing factor to the poor humoral i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323f132317546bf6bbf077cfb9b39d0a
https://doi.org/10.1016/j.imlet.2021.11.001
https://doi.org/10.1016/j.imlet.2021.11.001
Autor:
Kinga Grabowska, Magda Wąchalska, Małgorzata Graul, Michał Rychłowski, Krystyna Bieńkowska-Szewczyk, Andrea D. Lipińska
Publikováno v:
Viruses, Vol 12, Iss 4, p 429 (2020)
Herpesvirus envelope glycoprotein B (gB) is one of the best-documented extracellular vesicle (EVs)-incorporated viral proteins. Regarding the sequence and structure conservation between gB homologs, we asked whether bovine herpesvirus-1 (BoHV-1) and
Externí odkaz:
https://doaj.org/article/01bbf0491d0042288fd214cc8b909839
Publikováno v:
Neoplasia (New York, N.Y.)
Early lung carcinoma development may be modulated by innate host cellular mechanisms that promote tumor growth and invasion. We recently identified how a loss-of-function mutation in the glycan sulfating enzyme N-deacetylase/N-sulfotransferase-1 (Nds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c1a8c4e83557920ae120f81f6685b95
http://europepmc.org/articles/PMC8560828
http://europepmc.org/articles/PMC8560828
Autor:
Maurizio Federico
Publikováno v:
Cytokine & Growth Factor Reviews
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has given rise to the urgent need for vaccines and therapeutic interventions to address the spread of the SARS-CoV-2 virus. SARS-CoV-2 vaccines in development, and those being
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d440f076bbd18d0f54ba0ad3780228
https://doi.org/10.1016/j.cytogfr.2021.03.001
https://doi.org/10.1016/j.cytogfr.2021.03.001
Publikováno v:
Human Immunology
HLA alleles are associated with the body's response to infection and the regulation of the immune system. HLA alleles have been reported to be involved in response to viral infections such as SARS-CoV2. Our study reviews the HLA alleles associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11be348b671ff35e604d9189640d8ed9
https://doi.org/10.1016/j.humimm.2021.04.005
https://doi.org/10.1016/j.humimm.2021.04.005
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1493-1512 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1493-1512 (2021)
Macrophages are typically identified as classically activated (M1) macrophages and alternatively activated (M2) macrophages, which respectively exhibit pro- and anti-inflammatory phenotypes, and the balance between these two subtypes plays a critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ea92a17df434fa277efb35adc11fe4
https://doi.org/10.1016/j.apsb.2020.12.014
https://doi.org/10.1016/j.apsb.2020.12.014
Autor:
Goshi Shiota, Hiroyuki Tsuchiya
Publikováno v:
Tsuchiya, Hiroyuki. Shiota, Goshi. Immune evasion by cancer stem cells. Regenerative Therapy. 17. 20-33. doi:10.1016/j.reth.2021.02.006
Regenerative Therapy, Vol 17, Iss, Pp 20-33 (2021)
Regenerative Therapy
Regenerative Therapy, Vol 17, Iss, Pp 20-33 (2021)
Regenerative Therapy
Tumor immunity represents a new avenue for cancer therapy. Immune checkpoint inhibitors have successfully improved outcomes in several tumor types. In addition, currently, immune cell-based therapy is also attracting significant attention. However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6054a82a446a6f8b0b1100401e59a6
https://doi.org/10.1016/j.reth.2021.02.006
https://doi.org/10.1016/j.reth.2021.02.006
Autor:
Go, Du-Min, Lee, Seung Hyun, Lee, Su-Hyung, Woo, Sang-Ho, Kim, Kibyeong, Kim, Kyeongdae, Park, Kyu Seong, Park, Jong-Hwan, Ha, Sang-Jun, Kim, Woo Ho, Choi, Jae-Hoon, Kim, Dae-Yong
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Helicobacter pylori has been reported to modulate local immune responses to colonize persistently in gastric mucosa. Although the induced expression of programmed cell death ligand 1 (PD-L1) has been suggested as an immune modulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef8f6fcf149fca0f5b3eb28847252f65
http://europepmc.org/articles/PMC8267570
http://europepmc.org/articles/PMC8267570