Zobrazeno 1 - 10
of 19
pro vyhledávání: '"MGP, matrix Gla protein"'
Publikováno v:
JACC: Basic to Translational Science
Central Illustration
Highlights • Vascular calcification is a highly regulated, cell-mediated process that is strongly associated with CKD and confers increased risk for incident CV events. • Multiple pathways link vascular calcification wit
Highlights • Vascular calcification is a highly regulated, cell-mediated process that is strongly associated with CKD and confers increased risk for incident CV events. • Multiple pathways link vascular calcification wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e372c695df3f3abc3d2cbb7eb7aeb0
https://doi.org/10.1016/j.jacbts.2020.02.002
https://doi.org/10.1016/j.jacbts.2020.02.002
Autor:
Fabian Schulte, Putu Ustriyana, Farai Gombedza, Felicitas B. Bidlack, Ana Gil-Bona, William J. Landis, Markus Hardt, Nita Sahai, Sailaja Paruchuri
Publikováno v:
Bone Reports
Bone Reports, Vol 14, Iss, Pp 100754-(2021)
Bone Reports, Vol 14, Iss, Pp 100754-(2021)
Bone biomineralization is a complex process in which type I collagen and associated non-collagenous proteins (NCPs), including glycoproteins and proteoglycans, interact closely with inorganic calcium and phosphate ions to control the precipitation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00f6419061f40b341cd0126ebf78227
https://pubmed.ncbi.nlm.nih.gov/33665237
https://pubmed.ncbi.nlm.nih.gov/33665237
Autor:
Alawi A. Alsheikh-Ali, Bin Yu, Leah Ott, Ophélie Gourgas, Marta Cerruti, Benoit de Varennes, Anouar Hafiane, Hamood Al Kindi, Dominique Shum-Tim, Adel Schwertani, Jacques Genest, George Thanassoulis, Nial Filwood
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 4, Pp 358-371 (2017)
JACC: Basic to Translational Science
JACC: Basic to Translational Science
Visual Abstract
Highlights • Lp(a) significantly increased alkaline phosphatase activity, phosphate and calcium content, and matrix vesicle formation and induced apoptosis and calcification of normal human aortic valve interstitial cells. •
Highlights • Lp(a) significantly increased alkaline phosphatase activity, phosphate and calcium content, and matrix vesicle formation and induced apoptosis and calcification of normal human aortic valve interstitial cells. •
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0424038108b253766f655db4c0850b7
http://www.sciencedirect.com/science/article/pii/S2452302X17301341
http://www.sciencedirect.com/science/article/pii/S2452302X17301341
Autor:
Takehiro Hashikata, Minako Yamaoka-Tojo, Lisa Kitasato, Sayaka Namba, Naonobu Takahira, Takuya Hashimoto, Junya Ako, Takashi Masuda, Taiki Tojo, Yuki Ikeda, Takao Shimohama
Publikováno v:
BBA Clinical
Background Stroke prevention by warfarin, a vitamin K antagonist, has been an integral part in the management of atrial fibrillation. Vitamin K-dependent matrix Gla protein (MGP) has been known as a potent inhibitor of arterial calcification and oste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7262c20d6745576240e7974c5f23440
https://doi.org/10.1016/j.bbacli.2015.08.002
https://doi.org/10.1016/j.bbacli.2015.08.002
Publikováno v:
Journal of Nutritional Science
Vitamin K is considered to be involved in the pathological mechanisms of coronary artery calcification (CAC). Correlation between CAC and plasma vitamin K levels was studied. A total of 103 patients, with at least one coronary risk factor, were studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808ed5cc194533ad350c658b6e7f5ec7
https://pubmed.ncbi.nlm.nih.gov/28620475
https://pubmed.ncbi.nlm.nih.gov/28620475
Autor:
Renate M. L. Zwijsen, Lavienja A. J. L. M. Braam, Marjo H. J. Knapen, Elke Theuwissen, Kirsten J.F. Teunissen, Cees Vermeer
Publikováno v:
Journal of Nutritional Science, 4:e35. Cambridge University Press
Journal of Nutritional Science
Journal of Nutritional Science
Population-based studies have shown an inverse association between dietary menaquinones (MK-n, vitamin K2) intake, coronary calcification and CHD risk, suggesting a potential role of vitamin K in vascular health. To date, the effects of increased men
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09962db4726c5fca6ac6c2f64efc2da7
https://cris.maastrichtuniversity.nl/en/publications/2e5005ec-e052-4dfd-be3a-484a61d0fd94
https://cris.maastrichtuniversity.nl/en/publications/2e5005ec-e052-4dfd-be3a-484a61d0fd94
Autor:
Yucheng Yao, Aldons J. Lusis, Pierre J. Guihard, Ana M. Blazquez-Medela, Jiayi Yao, Kristina I. Boström, Medet Jumabay
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 5, Iss 1, Pp 257-263 (2015)
FEBS Open Bio, Vol 5, Iss 1, Pp 257-263 (2015)
Highlights • ABCC6 deficiency stimulates BMP signaling in multiple organs. • ABCC6 deficiency causes tissue-specific induction of BMP-related genes. • Tissue-specific targeting of BMP signaling may be needed in ABCC deficiency.
Mutations i
Mutations i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc696f2558e91dec8cdf040104736ef8
https://pubmed.ncbi.nlm.nih.gov/25893161
https://pubmed.ncbi.nlm.nih.gov/25893161
Akademický článek
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Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Golüke NMS; University Medical Center Utrecht, Department of Geriatrics, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands.; Tergooi Hospitals, Department of Geriatrics, Rijksstraatweg 1, 1261 AN Blaricum, the Netherlands., Schoffelmeer MA; University Medical Center Utrecht, Department of Geriatrics, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands., De Jonghe A; Tergooi Hospitals, Department of Geriatrics, Rijksstraatweg 1, 1261 AN Blaricum, the Netherlands., Emmelot-Vonk MH; University Medical Center Utrecht, Department of Geriatrics, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands., De Jong PA; University Medical Center Utrecht, Department of Radiology, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands., Koek HL; University Medical Center Utrecht, Department of Geriatrics, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands.
Publikováno v:
Bone reports [Bone Rep] 2022 Jun 18; Vol. 17, pp. 101599. Date of Electronic Publication: 2022 Jun 18 (Print Publication: 2022).