Výsledky vyhledávání - "MESOTHELIAL CELLS"

Akademický článek

Bone marrow mesenchymal stem cell-derived exosome inhibits high glucose-induced EMT of peritoneal mesothelial cells

Autor: ZHAO Junli, ZHU Junjun, ZHAN Qiunan, LIU Miao

Publikováno v: Jichu yixue yu linchuang, Vol 44, Iss 8, Pp 1149-1156 (2024)

Objective To investigate the effects of bone marrow mesenchymal stem cell-derived exosomes (BMSCs-Exo) on the regulation of epithelia-mesenchymal transition (EMT) in human peritoneal mesothelial cells (HPMCs) treated with glucose-based peritoneal dia

Externí odkaz: https://doaj.org/article/4038ddb2f33f46a4ae8045aef330f3b8

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Akademický článek

Effect of cellular senescence on the response of human peritoneal mesothelial cells to TGF-β

Autor: Edyta Kawka, Rebecca Herzog, Marcin Ruciński, Agnieszka Malińska, Markus Unterwurzacher, Juan Manuel Sacnun, Anja Wagner, Katarzyna Kowalska, Karol Jopek, Agata Kucz-Chrostowska, Klaus Kratochwill, Janusz Witowski

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Abstract Transforming growth factor β (TGF-β) is implicated in both mesothelial-to-mesenchymal transition (MMT) and cellular senescence of human peritoneal mesothelial cells (HPMCs). We previously showed that senescent HPMCs could spontaneously acq

Externí odkaz: https://doaj.org/article/2cb8718db5424f74bfee025654002816

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Akademický článek

Sterile inflammation of peritoneal membrane caused by peritoneal dialysis: focus on the communication between immune cells and peritoneal stroma

Autor: Hongyong Su, Rong Zou, Jinqi Su, Xiaocui Chen, Haijuan Yang, Ning An, Chen Yang, Jixin Tang, Huafeng Liu, Cuiwei Yao

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

Peritoneal dialysis is a widely used method for treating kidney failure. However, over time, the peritoneal structure and function can deteriorate, leading to the failure of this therapy. This deterioration is primarily caused by infectious and steri

Externí odkaz: https://doaj.org/article/0e2704a014ac43d384e00612b3783fac

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Akademický článek

Reciprocal crosstalk between Th17 and mesothelial cells promotes metastasis‐associated adhesion of ovarian cancer cells

Publikováno v: Clinical and Translational Medicine, Vol 14, Iss 4, Pp n/a-n/a (2024)

Abstract Background IL‐17A and TNF synergistically promote inflammation and tumorigenesis. Their interplay and impact on ovarian carcinoma (OC) progression are, however, poorly understood. We addressed this question focusing on mesothelial cells, w

Externí odkaz: https://doaj.org/article/34a4cb60682e4aa7997d2f9cd82ee079

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Akademický článek

Current developments in peritoneal glucose transport and sodium-glucose co-transporter 2 inhibitors during peritoneal dialysis

Autor: Fan Yang, Cong-hui Liu, Xiao-qi Wang, Xiao-jing Liu, Ya-nan Shi, Zhong-xin Li

Publikováno v: Linchuang shenzangbing zazhi, Vol 23, Iss 11, Pp 946-950 (2023)

As a novel widely used drug, sodium-glucose co-transporter (SGLT) 2 inhibitor may lower blood glucose in type 2 diabetics through blocking SGLT2 to curtain glucose reabsorption in proximal renal tubular cells. At the same time, this drug may bring si

Externí odkaz: https://doaj.org/article/ab6017f8380c40c58b4c9e020a70ff5c

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Akademický článek

Mechanisms of mesothelial cell response to viral infections: HDAC1-3 inhibition blocks poly(I:C)-induced type I interferon response and modulates the mesenchymal/inflammatory phenotype

Autor: Flavia Trionfetti, Claudia Montaldo, Ivan Caiello, Giulio Bontempi, Michela Terri, Marta Tiberi, Vanessa Marchant, Alessandro Domenici, Paolo Menè, Marco Cordani, Clemens Zwergel, Giusi Prencipe, Marta Ruiz-Ortega, Sergio Valente, Antonello Mai, Marco Tripodi, Raffaele Strippoli

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)

Infectious peritonitis is a leading cause of peritoneal functional impairment and a primary factor for therapy discontinuation in peritoneal dialysis (PD) patients. Although bacterial infections are a common cause of peritonitis episodes, emerging ev

Externí odkaz: https://doaj.org/article/f9646b558a1344f187e41e3deecc332e

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Akademický článek

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Akademický článek

HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells

Autor: Flavia Trionfetti, Tonino Alonzi, Giulio Bontempi, Michela Terri, Cecilia Battistelli, Claudia Montaldo, Federica Repele, Dante Rotili, Sergio Valente, Clemens Zwergel, Giulia Matusali, Fabrizio Maggi, Delia Goletti, Marco Tripodi, Antonello Mai, Raffaele Strippoli

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)

BackgroundDespite the significant progress achieved in understanding the pathology and clinical management of SARS-CoV-2 infection, still pathogenic and clinical issues need to be clarified. Treatment with modulators of epigenetic targets, i.e., epid

Externí odkaz: https://doaj.org/article/31d5bba3c72849e2ab6a5faf175fe1bc

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