Výsledky vyhledávání - "MESH : Viral Nonstructural Proteins/metabolism"

Plasma apolipoprotein H limits HCV replication and associates with response to NS3 protease inhibitors-based therapy

Autor: Matthew L. Albert, Yoann Barthe, Armanda Casrouge, Arnaud Fontanet, Stanislas Pol, Sylvie Lagaye, Hélène Fontaine, Vincent Mallet, Philippe Sultanik, Christophe Hézode, Estelle Mottez, Laurent Abel, Etienne Gayat, Céline Dorival, Fabrice Carrat, Jean-Pierre Bronowicki, Ioannis Theodorou

Publikováno v: Liver International
Liver International, Wiley-Blackwell, 2015, 35 (7), pp.1833-1844. ⟨10.1111/liv.12759⟩
Liver International, 2015, 35 (7), pp.1833-1844. ⟨10.1111/liv.12759⟩
Liver International, Wiley-Blackwell, 2015, 35 (7), pp.1833-1844. 〈10.1111/liv.12759〉

International audience; BACKGROUND & AIMS:Chronic infection with HCV remains a public health problem with approximately 150 million people infected worldwide. HCV intersects with lipid metabolism for replication and entry; and plasma concentrations o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90633f842d8de6ea3f7f4df0ad3c882d
https://doi.org/10.1111/liv.12759

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NS2 proteases from hepatitis C virus and related hepaciviruses share composite active sites and previously unrecognized intrinsic proteolytic activities

Autor: Brigitte Blumen, François Penin, Matthieu Fritz, Annette Martin, Célia Boukadida, Marie-Laure Fogeron

Publikováno v: PLoS Pathogens
PLoS Pathogens, 2018, 14 (2), pp.e1006863. ⟨10.1371/journal.ppat.1006863⟩
PLoS Pathogens, Vol 14, Iss 2, p e1006863 (2018)
PLoS Pathogens, Public Library of Science, 2018, 14 (2), pp.e1006863. ⟨10.1371/journal.ppat.1006863⟩

Over the recent years, several homologues with varying degrees of genetic relatedness to hepatitis C virus (HCV) have been identified in a wide range of mammalian species. HCV infectious life cycle relies on a first critical proteolytic event of its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96679972c4e7957811b757405d37d3a0
https://hal-pasteur.archives-ouvertes.fr/pasteur-02896778

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Mosquito Rasputin interacts with chikungunya virus nsP3 and determines the infection rate in Aedes albopictus

Autor: Fros, Jelke J, Geertsema, Corinne, Zouache, Karima, Baggen, Jim, Domeradzka, Natalia, van Leeuwen, Daniël M, Flipse, Jacky, Vlak, Just M, Failloux, Anna-Bella, Pijlman, Gorben P, LS Virologie, I&I SIB1, Infection & Immunity

Publikováno v: Parasites and Vectors
Parasites and Vectors, BioMed Central, 2015, 8 (1), pp.464. ⟨10.1186/s13071-015-1070-4⟩
Parasites & Vectors
Parasites & Vectors 8 (2015) 1
Parasites & Vectors, 8(1)
Parasites & Vectors, 2015, 8 (1), pp.464. ⟨10.1186/s13071-015-1070-4⟩
Parasites & Vectors, 8. BioMed Central

BACKGROUND: Chikungunya virus (CHIKV) is an arthritogenic alphavirus (family Togaviridae), transmitted by Aedes species mosquitoes. CHIKV re-emerged in 2004 with multiple outbreaks worldwide and recently reached the Americas where it has infected ove

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0df1ff677f0890b512f89a8d40fd875
https://hal-pasteur.archives-ouvertes.fr/pasteur-01678901/file/document.pdf

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Rotavirus NSP2 interferes with the core lattice protein VP2 in initiation of minus-strand synthesis

Autor: M. Alejandra Tortorici, Zenobia F. Taraporewala, John T. Patton, Patrice Vende

Publikováno v: Virology
Virology, Elsevier, 2003, 313 (1), pp.261-273. ⟨10.1016/S0042-6822(03)00302-7⟩

International audience; The rotavirus nonstructural protein NSP2 self-assembles into stable octameric structures that possess nonspecific affinity for single-stranded (ss)RNA and RNA-RNA helix-destabilizing and NTPase activities. Furthermore, NSP2 is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a703cd3c85478366e0eaa8f4513243
https://doi.org/10.1016/s0042-6822(03)00302-7

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Species-specific impact of the autophagy machinery on Chikungunya virus infection

Autor: Nicolas Gangneux, Mickaël Lelek, Marie-Christine Prévost, Mehdi Bouraï, Yves Jacob, Pierre-Olivier Vidalain, Thérèse Couderc, Marc Lecuit, Marianne Lucas-Hourani, Serge Mostowy, Christophe Zimmer, Delphine Judith, Philippe Pierre, Nadège Cayet, Frédéric Tangy

Publikováno v: EMBO Reports
EMBO Reports, EMBO Press, 2013, 14 (6), pp.534-544. ⟨10.1038/embor.2013.51⟩
EMBO Reports, 2013, 14 (6), pp.534-544. ⟨10.1038/embor.2013.51⟩
EMBO reports

Comment in : Macroautophagy--friend or foe of viral replication? [EMBO Rep. 2013]; International audience; Chikungunya virus (CHIKV) is a recently re-emerged arbovirus that triggers autophagy. Here, we show that CHIKV interacts with components of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48d408100c2b59070050ade1ec46ed7
https://hal-pasteur.archives-ouvertes.fr/pasteur-02447347

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Role of Bunyamwera Orthobunyavirus NSs Protein in Infection of Mosquito Cells

Autor: Anna-Bella Failloux, Richard M. Elliott, Agnieszka M. Szemiel

Publikováno v: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2012, 6 (9), pp.e1823. ⟨10.1371/journal.pntd.0001823⟩
PLoS Neglected Tropical Diseases, 2012, 6 (9), pp.e1823. ⟨10.1371/journal.pntd.0001823⟩
PLoS Neglected Tropical Diseases, Vol 6, Iss 9, p e1823 (2012)

Background Bunyamwera orthobunyavirus is both the prototype and study model of the Bunyaviridae family. The viral NSs protein seems to contribute to the different outcomes of infection in mammalian and mosquito cell lines. However, only limited infor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01adff217c22b3055ca6605c1d08d03
https://hal-pasteur.archives-ouvertes.fr/pasteur-01680988/document

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