Zobrazeno 1 - 10
of 780
pro vyhledávání: '"MESH : Transcription Factors"'
Autor:
Marchal-Duval, Emmeline, Homps-Legrand, Méline, Froidure, Antoine, Jaillet, Madeleine, Ghanem, Mada, Lou, Deneuville, Justet, Aurélien, Maurac, Arnaud, Vadel, Aurelie, Fortas, Emilie, Cazes, Aurelie, Joannes, Audrey, Giersh, Laura, Mal, Herve, Mordant, Pierre, Piolot, Tristan, Truchin, Marin, Mounier, Carine, Schirduan, Ksenija, Korfei, Martina, Gunther, Andreas, Mari, Bernard, Jaschinski, Frank, Crestani, Bruno, Mailleux, Arnaud
Publikováno v:
eLife, Vol. 12, no.1, p. 1-32 (2023)
eLife
eLife, 2023, 12, pp.e79840. ⟨10.7554/eLife.79840⟩
eLife
eLife, 2023, 12, pp.e79840. ⟨10.7554/eLife.79840⟩
Matrix remodeling is a salient feature of idiopathic pulmonary fibrosis (IPF). Targeting cells driving matrix remodeling could be a promising avenue for IPF treatment. Analysis of transcriptomic database identified the mesenchymal transcription facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1996ed1dcf65d6fdb8ee48a755b89e39
https://hdl.handle.net/2078.1/276007
https://hdl.handle.net/2078.1/276007
Autor:
Magali Charvin, Thierry Halter, Romain Blanc-Mathieu, Pierre Barraud, Magali Aumont-Nicaise, François Parcy, Lionel Navarro
Publikováno v:
Plant Physiology
Plant Physiology, 2023, 192 (1), pp.77-84. ⟨10.1093/plphys/kiad069⟩
Plant Physiology, 2023, 192 (1), pp.77-84. ⟨10.1093/plphys/kiad069⟩
DNA methylation is an epigenetic mark that fine-tunes gene expression, notably by negatively or positively regulating transcription factor (TF)-DNA binding. In plants, DNA methylation has primarily been shown to inhibit TF-DNA binding. However, littl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cddfafd797eae3befdcb62bba96afdc
https://hal.science/hal-04097425/document
https://hal.science/hal-04097425/document
Publikováno v:
Plant and Cell Physiology
Plant and Cell Physiology, Oxford University Press (OUP), 2021, 62 (3), pp.392-400. ⟨10.1093/pcp/pcab016⟩
Plant and Cell Physiology, Oxford University Press (OUP), 2021, 62 (3), pp.392-400. ⟨10.1093/pcp/pcab016⟩
Phosphate (Pi) deficiency is a major factor limiting plant productivity worldwide. Land plants have evolved different strategies to cope with Pi deficiency. For instance, plants activate the so-called Pi starvation response (PSR) system, which is reg
Autor:
Arnault, Tauziède-Espariat, Aurore, Siegfried, Yvan, Nicaise, Dominique, Figarella-Branger, Romain, Appay, Suhan, Senova, Dorian, Bochaton, Lauren, Hasty, Anna, Martin, Fabrice, Chrétien, Alice, Métais, Pascale, Varlet, Emmanuelle, Uro-Coste
Publikováno v:
Brain Tumor Pathology
Brain Tumor Pathology, 2022, 39 (4), pp.240-242. ⟨10.1007/s10014-022-00439-0⟩
Brain Tumor Pathology, 2022, 39 (4), pp.240-242. ⟨10.1007/s10014-022-00439-0⟩
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e008b003acb8788830562be22ce3a0a1
https://hal-amu.archives-ouvertes.fr/hal-03982121
https://hal-amu.archives-ouvertes.fr/hal-03982121
Autor:
Cosima M. Schmid, Anne Gregor, Gregory Costain, Chantal F. Morel, Lauren Massingham, Jennifer Schwab, Chloé Quélin, Marie Faoucher, Julie Kaplan, Rebecca Procopio, Carol J. Saunders, Ana S.A. Cohen, Gabrielle Lemire, Stephanie Sacharow, Anne O’Donnell-Luria, Ranit Jaron Segal, Jessica Kianmahd Shamshoni, Daniela Schweitzer, Darius Ebrahimi-Fakhari, Kristin Monaghan, Timothy Blake Palculict, Melanie P. Napier, Alice Tao, Bertrand Isidor, Kamran Moradkhani, André Reis, Heinrich Sticht, Wendy K. Chung, Christiane Zweier
Publikováno v:
Genetics in Medicine
Genetics in Medicine, 2023, 25 (7), pp.100839. ⟨10.1016/j.gim.2023.100839⟩
Genetics in Medicine, 2023, 25 (7), pp.100839. ⟨10.1016/j.gim.2023.100839⟩
PURPOSE LHX2 encodes the LIM homeobox 2 transcription factor (LHX2), which is highly expressed in brain and well conserved across species, but has not been clearly linked to neurodevelopmental disorders (NDD) to date. METHODS Through international co
Autor:
Roman Rohac, Jason C. Crack, Eve de Rosny, Océane Gigarel, Nick E. Le Brun, Juan C. Fontecilla-Camps, Anne Volbeda
Publikováno v:
Communications Biology
Communications Biology, 2022, 5 (1), pp.769. ⟨10.1038/s42003-022-03745-7⟩
Communications Biology, 2022, 5 (1), pp.769. ⟨10.1038/s42003-022-03745-7⟩
Several transcription factors of the Rrf2 family use an iron-sulfur cluster to regulate DNA binding through effectors such as nitric oxide (NO), cellular redox status and iron levels. [4Fe-4S]-NsrR from Streptomyces coelicolor (ScNsrR) modulates expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acfef05a7159a568c983dbb2ac31b768
https://hal.science/hal-03745259
https://hal.science/hal-03745259
Autor:
I K Temple, Sandra Chantot-Bastaraud, Jose María Lloreda-García, Maria Olmo-Sanchez, Cristina De la Torre-Sandoval, Jose Ramón Fernández-Fructuoso, Madeleine D. Harbison, Irene Netchine
Publikováno v:
Clinical Dysmorphology
Clinical Dysmorphology, 2021, 30 (4), pp.194-196. ⟨10.1097/MCD.0000000000000375⟩
Clinical Dysmorphology, 2021, 30 (4), pp.194-196. ⟨10.1097/MCD.0000000000000375⟩
Silver Russell syndrome (SRS) is a congenital disorder characterised by intrauterine growth retardation (IUGR), feeding difficulties and postnatal growth retardation. In a small number of cases PLAG1 variants have been described (OMIM #618907). PLAG1
Autor:
Guillaume Jouret, Solveig Heide, Arthur Sorlin, Laurence Faivre, Sandra Chantot‐Bastaraud, Claire Beneteau, Marie Denis‐Musquer, Peter D. Turnpenny, Charles Coutton, Gaëlle Vieville, Julien Thevenon, Austin Larson, Florence Petit, Elise Boudry, Thomas Smol, Bruno Delobel, Bénédicte Duban‐Bedu, Chiara Fallerini, Francesca Mari, Caterina Lo Rizzo, Alessandra Renieri, Jean‐Hubert Caberg, Anne‐Sophie Denommé‐Pichon, Frédéric Tran Mau‐Them, Isabelle Maystadt, Thomas Courtin, Boris Keren, Linda Mouthon, Perrine Charles, Silvestre Cuinat, Bertrand Isidor, Philippe Theis, Christian Müller, Marizela Kulisic, Seval Türkmen, Daniel Stieber, Dominique Bourgeois, Emmanuel Scalais, Barbara Klink
Publikováno v:
Clinical Genetics
Clinical Genetics, 2022, 102 (2), pp.117-122. ⟨10.1111/cge.14141⟩
Clinical Genetics, 2022, 102 (2), pp.117-122. ⟨10.1111/cge.14141⟩
International audience; BRD4 is part of a multiprotein complex involved in loading the cohesin complex onto DNA, a fundamental process required for cohesin-mediated loop extrusion and formation of Topologically Associating Domains. Pathogenic variati
Publikováno v:
Genetica
Genetica, Springer Verlag, 2020, 148 (5-6), pp.243-251. ⟨10.1007/s10709-020-00102-6⟩
Genetica, 2020, 148 (5-6), pp.243-251. ⟨10.1007/s10709-020-00102-6⟩
Genetica, Springer Verlag, 2020, 148 (5-6), pp.243-251. ⟨10.1007/s10709-020-00102-6⟩
Genetica, 2020, 148 (5-6), pp.243-251. ⟨10.1007/s10709-020-00102-6⟩
International audience; Gibberellic acid (GA) is a major plant hormone involved in several biological processes from the flowering to the symbiosis with microorganisms. Thus, the GA regulation is crucial for plant biology. This regulation occurs via
Publikováno v:
Biomolecular NMR Assignments
Biomolecular NMR Assignments, 2022, 16 (2), pp.257-266. ⟨10.1007/s12104-022-10089-0⟩
Biomolecular NMR Assignments, 2022, 16 (2), pp.257-266. ⟨10.1007/s12104-022-10089-0⟩
International audience; HSP90 is a major molecular chaperone that helps both folding and stabilization of various client proteins often implicated in growth control and cell survival such as kinases and transcription factors. However, among HSP90 cli