Zobrazeno 1 - 10
of 73
pro vyhledávání: '"MESH : Thiazoles"'
Autor:
Nicolas Barnich, Sébastien Massier, Richard Bonnet, Emilie Vazeille, Guillaume Dalmasso, Hang Thi Thu Nguyen, Tiphanie Faïs, Julien Delmas, Caroline Chevarin
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2021, 22 (7), pp.1-17. ⟨10.3390/ijms22073512⟩
Volume 22
Issue 7
International Journal of Molecular Sciences, MDPI, 2021, 22 (7), pp.1-17. ⟨10.3390/ijms22073512⟩
International Journal of Molecular Sciences, Vol 22, Iss 3512, p 3512 (2021)
International Journal of Molecular Sciences, 2021, 22 (7), pp.1-17. ⟨10.3390/ijms22073512⟩
Volume 22
Issue 7
International Journal of Molecular Sciences, MDPI, 2021, 22 (7), pp.1-17. ⟨10.3390/ijms22073512⟩
International Journal of Molecular Sciences, Vol 22, Iss 3512, p 3512 (2021)
International audience; Background: Adherent-invasive Escherichia coli (AIEC) have been implicated in the etiology of Crohn’s disease. The AIEC reference strain LF82 possesses a pathogenicity island similar to the high pathogenicity island of Yersi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db510b8b2134c43de93c97c733caef56
https://hal.inrae.fr/hal-03318629
https://hal.inrae.fr/hal-03318629
Autor:
Gerald Larrouy-Maumus, Sandrine Favre-Rochex, Alessandro Cascioferro, Hélène Munier-Lehmann, Sonia Rebollo-Ramirez, Claire Beauvineau, Delphine Naud-Martin, Mena Cimino, Brigitte Gicquel, Maria Virginia Buchieri, Olivier Helynck
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2017, 60 (17), pp.7425-7433. ⟨10.1021/acs.jmedchem.7b00726⟩
Journal of Medicinal Chemistry, 2017, 60 (17), pp.7425-7433. ⟨10.1021/acs.jmedchem.7b00726⟩
Journal of Medicinal Chemistry, American Chemical Society, 2017, 60 (17), pp.7425-7433. ⟨10.1021/acs.jmedchem.7b00726⟩
Journal of Medicinal Chemistry, 2017, 60 (17), pp.7425-7433. ⟨10.1021/acs.jmedchem.7b00726⟩
International audience; In this study, we aimed to decipher the natural resistance mechanisms of mycobacteria against novel compounds isolated by whole-cell-based high-throughput screening (HTS). We identified active compounds using Mycobacterium aur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc121eccd96b56ad0e81344220e3315b
https://doi.org/10.1021/acs.jmedchem.7b00726
https://doi.org/10.1021/acs.jmedchem.7b00726
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (31), pp.8229-8234. ⟨10.1073/pnas.1702192114⟩
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (31), pp.8229-8234. ⟨10.1073/pnas.1702192114⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (31), pp.8229-8234. ⟨10.1073/pnas.1702192114⟩
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (31), pp.8229-8234. ⟨10.1073/pnas.1702192114⟩
International audience; Thyroid hormone receptors (TRs) are members of the nuclear hormone receptor superfamily that act as ligand-dependent transcription factors. Here we identified the ten-eleven translocation protein 3 (TET3) as a TR interacting p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf2b53766639fbc3f46a5f35c84cc8c
https://doi.org/10.1073/pnas.1702192114
https://doi.org/10.1073/pnas.1702192114
Autor:
Cristina Bulai Livideanu, Olivier Hermine, Carle Paul, Sophie georgin Lavialle, Sylvie Fraitag, Katia Hanssens, Clive Grattan, Gérard Guillet, Gandhi Damaj, Marie-Olivia Chandesris, Jean-Pierre Kinet, Raphaël Gaillard, Laurent Frenzel, Lawrence B. Afrin, Danielle Canioni, Stéphane Barete, Ludovic Lhermitte, Srdan Verstovsek, Christian Auclair, Ewa Jassem, Julie Agopian, Colin Mansfield, Olivier Lortholary, Patrice Dubreuil, Alain Moussy, Marek Niedoszytko
Publikováno v:
The Lancet
The Lancet, Elsevier, 2017, 389 (10069), pp.612-620. ⟨10.1016/S0140-6736(16)31403-9⟩
The Lancet, 2017, 389 (10069), pp.612-620. ⟨10.1016/S0140-6736(16)31403-9⟩
The Lancet, Elsevier, 2017, 389 (10069), pp.612-620. ⟨10.1016/S0140-6736(16)31403-9⟩
The Lancet, 2017, 389 (10069), pp.612-620. ⟨10.1016/S0140-6736(16)31403-9⟩
Summary Background Indolent systemic mastocytosis, including the subvariant of smouldering systemic mastocytosis, is a lifelong condition associated with reduced quality of life. Masitinib inhibits KIT and LYN kinases that are involved in indolent sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c5746cab0c984508b5cd7c8f0c98bb
https://doi.org/10.1016/s0140-6736(16)31403-9
https://doi.org/10.1016/s0140-6736(16)31403-9
Autor:
Pavel Macek, Jonathan P. Waltho, J. Willem M. Nissink, Matthew J. Cliff, Kevin J. Embrey, Rick Davies, Martin Blackledge, Stanislava Panova, Malene Ringkjøbing Jensen
Publikováno v:
Structure
Structure, Elsevier (Cell Press), 2019, 27 (10), pp.1537-1546.e4. ⟨10.1016/j.str.2019.07.006⟩
Panova, S, Cliff, M, Macek, P, Blackledge, M, Jensen, M R, Nissink, J W M, Embrey, K J, Davies, R & Waltho, J 2019, ' Mapping hidden residual structure within the Myc bHLH-LZ domain using chemical denaturant titration ', Structure . https://doi.org/10.1016/j.str.2019.07.006
Structure, 2019, 27 (10), pp.1537-1546.e4. ⟨10.1016/j.str.2019.07.006⟩
Structure, Elsevier (Cell Press), 2019, 27 (10), pp.1537-1546.e4. ⟨10.1016/j.str.2019.07.006⟩
Panova, S, Cliff, M, Macek, P, Blackledge, M, Jensen, M R, Nissink, J W M, Embrey, K J, Davies, R & Waltho, J 2019, ' Mapping hidden residual structure within the Myc bHLH-LZ domain using chemical denaturant titration ', Structure . https://doi.org/10.1016/j.str.2019.07.006
Structure, 2019, 27 (10), pp.1537-1546.e4. ⟨10.1016/j.str.2019.07.006⟩
International audience; Intrinsically disordered proteins (IDPs) underpin biological regulation and hence are highly desirable drug-development targets. NMR is normally the tool of choice for studying the conformational preferences of IDPs, but the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2279504f4c486d035e0b61eb94e5db50
https://hal.univ-grenoble-alpes.fr/hal-03016176/document
https://hal.univ-grenoble-alpes.fr/hal-03016176/document
Autor:
Christian Trepo, Michael P. Manns, David Wright, Jose Luis Calleja, Peter W. White, Chan-Loi Yong, Stanislas Pol, George Kukolj, Jerry O. Stern, Marc Bourlière, Maurizio Bonacini, Thomas Berg, Wulf Otto Boecher, Yves Benhamou, Gerhard G. Steinmann, Joe Scherer
Publikováno v:
Journal of Hepatology
Journal of Hepatology, Elsevier, 2011, 54 (6), pp.1114-22. ⟨10.1016/j.jhep.2010.08.040⟩
Journal of Hepatology, Elsevier, 2011, 54 (6), pp.1114-22. 〈10.1016/j.jhep.2010.08.040〉
Journal of Hepatology, Elsevier, 2011, 54 (6), pp.1114-22. ⟨10.1016/j.jhep.2010.08.040⟩
Journal of Hepatology, Elsevier, 2011, 54 (6), pp.1114-22. 〈10.1016/j.jhep.2010.08.040〉
International audience; BACKGROUND & AIMS: BI201335 is a highly specific and potent HCV protease inhibitor. This multiple rising dose trial evaluated antiviral activity and safety in chronic HCV genotype-1 patients. METHODS: Thirty-four treatment-na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947da88215c342d73ca0ef790ae3bfd6
https://doi.org/10.1016/j.jhep.2010.08.040
https://doi.org/10.1016/j.jhep.2010.08.040
Autor:
Mohammad Javad Mokhtari, A Farhangi, M R Mehrabi, Mehri Mortazavi, Hosseinian Z, Zahra Saffari, Azim Akbarzadeh
Publikováno v:
Pakistan Journal of Biological Sciences
Pakistan Journal of Biological Sciences, Asian Network for Scientific Information (ANSINET), 2011, 14 (2), pp.128-32. ⟨10.3923/pjbs.2011⟩
Pakistan Journal of Biological Sciences, Asian Network for Scientific Information (ANSINET), 2011, 14 (2), pp.128-32. ⟨10.3923/pjbs.2011⟩
International audience; The aim of this study was to investigate the antiproliferative proteins that probably have a role in Helicobacter pylori evade of immune response and cause chronic infection disease and also to see if coccoid form had a role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d70d97ec85169317156d3ebb81375a
https://doi.org/10.3923/pjbs.2011.128.132
https://doi.org/10.3923/pjbs.2011.128.132
Autor:
Milos V. Novotny, Helena A. Soini, Claude Baudoin, Donald Wiesler, Christophe Féron, Sachiko Koyama
Publikováno v:
Journal of Chemical Ecology
Journal of Chemical Ecology, Springer Verlag, 2009, 35 (5), pp.580-9. ⟨10.1007/s10886-009-9628-2⟩
Journal of Chemical Ecology, Springer Verlag, 2009, 35 (5), pp.580-9. ⟨10.1007/s10886-009-9628-2⟩
International audience; Whereas the house mouse (Mus domesticus) has been studied extensively in terms of physiology/behavior and pheromonal attributes, the evolutionarily related mound-building mouse (Mus spicilegus) has received attention only rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6a9b5855f39ff106212b2057075417
https://doi.org/10.1007/s10886-009-9628-2
https://doi.org/10.1007/s10886-009-9628-2
Autor:
Serge Roche, Franck E. Nicolini, Cédric Leroy, Coralie Belanger, Sandrine Hayette, Paul W. Manley, Jean-Max Pasquet, Béatrice Turcq, Francis Belloc, Valérie Lagarde, Francois-Xavier Mahon, Gabriel Etienne
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2008, 68 (23), pp.9809-9816. ⟨10.1158/0008-5472.CAN-08-1008⟩
Cancer Research, American Association for Cancer Research, 2008, 68 (23), pp.9809-9816. ⟨10.1158/0008-5472.CAN-08-1008⟩
Targeting the tyrosine kinase activity of Bcr-Abl is an attractive therapeutic strategy in chronic myeloid leukemia (CML) and in Bcr-Abl–positive acute lymphoblastic leukemia. Whereas imatinib, a selective inhibitor of Bcr-Abl tyrosine kinase, is n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909a493563e6fd6597a87e2304b0e161
https://doi.org/10.1158/0008-5472.can-08-1008
https://doi.org/10.1158/0008-5472.can-08-1008
Autor:
Béatrice Blot, Flavie Strappazzon, Rémy Sadoul, Sakina Torch, Yaël Trioulier, Jean Marc Verna
Publikováno v:
Molecular and Cellular Neuroscience
Molecular and Cellular Neuroscience, Elsevier, 2007, 34 (3), pp.355-65. ⟨10.1016/j.mcn.2006.11.012⟩
Molecular and Cellular Neuroscience, 2007, 34 (3), pp.355-65. ⟨10.1016/j.mcn.2006.11.012⟩
Molecular and Cellular Neuroscience, Elsevier, 2007, 34 (3), pp.355-65. ⟨10.1016/j.mcn.2006.11.012⟩
Molecular and Cellular Neuroscience, 2007, 34 (3), pp.355-65. ⟨10.1016/j.mcn.2006.11.012⟩
International audience; Numerous extracellular stimuli trigger trans-autophosphorylation at Tyr402 of Pyk2, inducing its activation. Pyk2 is a key mediator of several signaling pathways and has been implicated in apoptosis induced by specific stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30abbd5bcecc51395f16569df96163c5
https://doi.org/10.1016/j.mcn.2006.11.012
https://doi.org/10.1016/j.mcn.2006.11.012