Capsular Switching in Group B Streptococcus CC17 Hypervirulent Clone: A Future Challenge for Polysaccharide Vaccine Development

Autor: Agnès Fouet, Claire Poyart, Anne Six, Samuel Bellais, Philippe Glaser, Magalie Longo, Patrick Trieu-Cuot, Nicolas Dmytruk

Publikováno v: Journal of Infectious Diseases
Journal of Infectious Diseases, Oxford University Press (OUP), 2012, 206 (11), pp.1745-1752. ⟨10.1093/infdis/jis605⟩
Journal of Infectious Diseases, 2012, 206 (11), pp.1745-1752. ⟨10.1093/infdis/jis605⟩
Journal of Infectious Diseases, Oxford University Press (OUP), 2012, 206 (11), pp.1745-1752. 〈10.1093/infdis/jis605〉

Background. The capsular polysaccharide (CPS) is an important virulence factor and a vaccine target of the major neonatal pathogen group B Streptococcus (GBS). Population studies revealed no strong correlation between CPS type and multilocus sequence

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https://hal-pasteur.archives-ouvertes.fr/pasteur-01300172