Zobrazeno 1 - 10
of 15
pro vyhledávání: '"MESH : Retinal Degeneration"'
Autor:
Hamon, Annaïg, Masson, Christel, Bitard, Juliette, Gieser, Linn, Roger, Jérôme E., Perron, Muriel
Publikováno v:
Investigative Ophthalmology & Visual Science
Investigative Ophthalmology & Visual Science, Association for Research in Vision and Ophthalmology, 2017, 58 (4), pp.1941-1953. ⟨10.1167/iovs.16-21366⟩
Investigative Ophthalmology & Visual Science, Association for Research in Vision and Ophthalmology, 2017, 58 (4), pp.1941-1953. ⟨10.1167/iovs.16-21366⟩
Purpose During retinal degeneration, Müller glia cells respond to photoreceptor loss by undergoing reactive gliosis, with both detrimental and beneficial effects. Increasing our knowledge of the complex molecular response of Müller cells to retinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a217c51fc5bff753b1a6a042c64ece31
http://europepmc.org/articles/PMC6024660
http://europepmc.org/articles/PMC6024660
Autor:
Jean-Claude Jeanny, Francine Behar-Cohen, Christophe Klein, Laurent Jonet, Marie-Christine Naud, Antonin Oudar, Marianne Berdugo, Stéphane Galiacy, Quentin Le Rouzic, Charlotte Andrieu-Soler, Mohamed El Sanharawi, Hélène Coppin, Yves Courtois, François Malecaze, Marie-Paule Roth, Emilie Picard, Chloé Latour
Publikováno v:
Free Radical Biology and Medicine, vol. 89, pp. 1105-1121
Free Radical Biology and Medicine
Free Radical Biology and Medicine, Elsevier, 2015, 89, pp.1105-1121. ⟨10.1016/j.freeradbiomed.2015.08.018⟩
Free Radical Biology and Medicine, 2015, 89, pp.1105-1121. ⟨10.1016/j.freeradbiomed.2015.08.018⟩
Free Radical Biology and Medicine
Free Radical Biology and Medicine, Elsevier, 2015, 89, pp.1105-1121. ⟨10.1016/j.freeradbiomed.2015.08.018⟩
Free Radical Biology and Medicine, 2015, 89, pp.1105-1121. ⟨10.1016/j.freeradbiomed.2015.08.018⟩
International audience; Iron is essential for retinal function but contributes to oxidative stress-mediated degeneration. Iron retinal homeostasis is highly regulated and transferrin (Tf), a potent iron chelator, is endogenously secreted by retinal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e304190f4c2d0544571e34e0b362c4d5
https://doi.org/10.1016/j.freeradbiomed.2015.08.018
https://doi.org/10.1016/j.freeradbiomed.2015.08.018
Autor:
Serge Picaud, José-Alain Sahel, Antoine Chaffiol, Jens Duebel, Deniz Dalkara, Ernst Bamberg, Emilie Mace, Romain Caplette, Abhishek Sengupta, Olivier Marre, Melissa Desrosiers, Peggy Barbe
Publikováno v:
Molecular Therapy
Molecular Therapy, 2015, 23 (1), pp.7-16. ⟨10.1038/mt.2014.154⟩
Molecular Therapy, 2015, 23 (1), pp.7-16. ⟨10.1038/mt.2014.154⟩
International audience; Most inherited retinal dystrophies display progressive photoreceptor cell degeneration leading to severe visual impairment. Optogenetic reactivation of retinal neurons mediated by adeno-associated virus (AAV) gene therapy has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0edefb948e8361eae0ef63b2c0fdaed
https://doi.org/10.1038/mt.2014.154
https://doi.org/10.1038/mt.2014.154
Autor:
William Rostène, Julie Frugier, Françoise Baleux, David Godefroy, Isabelle Célérier, Serge Picaud, Françoise Brignole-Baudouin, Julie Degardin, Jeffrey K. Harrison, Christophe Baudouin, José Sahel, Alexandre Denoyer
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2012, 7 (6), pp.e37873. ⟨10.1371/journal.pone.0037873⟩
PLoS ONE, Public Library of Science, 2012, 7 (6), pp.e37873. 〈10.1371/journal.pone.0037873〉
PLoS ONE, Vol 7, Iss 6, p e37873 (2012)
PLoS ONE, 2012, 7 (6), pp.e37873. ⟨10.1371/journal.pone.0037873⟩
PLoS ONE, Public Library of Science, 2012, 7 (6), pp.e37873. ⟨10.1371/journal.pone.0037873⟩
PLoS ONE, Public Library of Science, 2012, 7 (6), pp.e37873. 〈10.1371/journal.pone.0037873〉
PLoS ONE, Vol 7, Iss 6, p e37873 (2012)
PLoS ONE, 2012, 7 (6), pp.e37873. ⟨10.1371/journal.pone.0037873⟩
International audience; Glaucoma, the most common cause of irreversible blindness, is a neuropathy commonly initiated by pathological ocular hypertension due to unknown mechanisms of trabecular meshwork degeneration. Current antiglaucoma therapy does
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f2117383dc58fb64ab823fe3a14537
https://pubmed.ncbi.nlm.nih.gov/22675496
https://pubmed.ncbi.nlm.nih.gov/22675496
Autor:
Christophe Combadière, William Raoul, Bertrand Calippe, Laurent Jonet, Serge Camelo, Olivier Levy, Florian Sennlaub, Xavier Guillonneau, Sophie Lavalette, Marianne Houssier, Sylvain Chemtob, Francine Behar-Cohen
Publikováno v:
American Journal of Pathology
American Journal of Pathology, American Society for Investigative Pathology, 2011, 178 (5), pp.2416-23. ⟨10.1016/j.ajpath.2011.01.013⟩
American Journal of Pathology, American Society for Investigative Pathology, 2011, 178 (5), pp.2416-23. 〈10.1016/j.ajpath.2011.01.013〉
American Journal of Pathology, 2011, 178 (5), pp.2416-23. ⟨10.1016/j.ajpath.2011.01.013⟩
American Journal of Pathology, American Society for Investigative Pathology, 2011, 178 (5), pp.2416-23. ⟨10.1016/j.ajpath.2011.01.013⟩
American Journal of Pathology, American Society for Investigative Pathology, 2011, 178 (5), pp.2416-23. 〈10.1016/j.ajpath.2011.01.013〉
American Journal of Pathology, 2011, 178 (5), pp.2416-23. ⟨10.1016/j.ajpath.2011.01.013⟩
International audience; The pro-inflammatory cytokine IL-1β has been shown to promote angiogenesis. It can have a neurotoxic or neuroprotective effect. Here, we have studied the expression of IL-1β in vivo and the effect of the IL-1 receptor antago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd56293f319e4ba55534242a10ab7bfa
https://www.hal.inserm.fr/inserm-00690746/document
https://www.hal.inserm.fr/inserm-00690746/document
Autor:
Jeanny, Jean-Claude, Picard, Émilie, Sergeant, Claire, Jonet, Laurent, Yefimova, Marina, Courtois, Yves
Publikováno v:
Bulletin de l'Académie Nationale de Médecine
Bulletin de l'Académie Nationale de Médecine, 2013, 197 (3), pp.661-74; discussion 674-5
Bulletin de l'Académie Nationale de Médecine, Elsevier Masson, 2013, 197 (3), pp.661-74; discussion 674-5
Bulletin de l'Académie Nationale de Médecine, 2013, 197 (3), pp.661-74; discussion 674-5
Bulletin de l'Académie Nationale de Médecine, Elsevier Masson, 2013, 197 (3), pp.661-74; discussion 674-5
International audience; Iron is necessary for cell metabolism, but excess iron can be toxic Iron can generate oxygen free radicals through the Fenton reaction. Iron accumulation has been observed in the retina of patients with age-related macular deg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5fdfd86b0618d75352c63a58166e8ebe
https://www.hal.inserm.fr/inserm-02983671
https://www.hal.inserm.fr/inserm-02983671
Autor:
Jean-Claude, Jeanny, Emilie, Picard, Claire, Sergeant, Laurent, Jonet, Marina, Yefimova, Yves, Courtois
Publikováno v:
Bulletin de l'Académie Nationale de Médecine
Bulletin de l'Académie Nationale de Médecine, 2013, 197 (3), pp.661-74; discussion 674-5
Bulletin de l'Académie Nationale de Médecine, 2013, 197 (3), pp.661-74; discussion 674-5
Iron is necessary for cell metabolism, but excess iron can be toxic Iron can generate oxygen free radicals through the Fenton reaction. Iron accumulation has been observed in the retina of patients with age-related macular degeneration (AMD). We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e94f23757d58a67e167f6a12a0c16716
https://www.hal.inserm.fr/inserm-02983671
https://www.hal.inserm.fr/inserm-02983671
Autor:
Jean-Claude Jeanny, Laurent Jonet, Isabelle Ranchon-Cole, Francine Behar-Cohen, Carole Beaumont, Yves Courtois, Emilie Picard
Publikováno v:
Investigative Ophthalmology & Visual Science
Investigative Ophthalmology & Visual Science, 2011, 52 (3), pp.1261. ⟨10.1167/iovs.10-5705⟩
Investigative Ophthalmology & Visual Science, Association for Research in Vision and Ophthalmology, 2011, 52 (3), pp.1261. ⟨10.1167/iovs.10-5705⟩
Investigative Ophthalmology & Visual Science, 2011, 52 (3), pp.1261. ⟨10.1167/iovs.10-5705⟩
Investigative Ophthalmology & Visual Science, Association for Research in Vision and Ophthalmology, 2011, 52 (3), pp.1261. ⟨10.1167/iovs.10-5705⟩
International audience; Purpose: Retinal degeneration is associated with iron accumulation in several rodent models in which iron-regulating proteins are impaired. Oxidative stress is catalyzed by unbound iron.Methods: The role of the heavy chain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32837bfc6abf1d776bf1f55af28072e2
https://pubmed.ncbi.nlm.nih.gov/20881284
https://pubmed.ncbi.nlm.nih.gov/20881284
Autor:
Picard, Émilie, Jonet, Laurent, Sergeant, Claire, Vesvres, Marie-Hélène, Behar-Cohen, Francine, Courtois, Yves, Jeanny, Jean-Claude
Publikováno v:
Molecular Vision, vol. 16, pp. 2612-2625
Molecular Vision
Molecular Vision, Molecular Vision, 2010, 16, pp.2612-25
Molecular Vision, 2010, 16, pp.2612-25
Molecular Vision
Molecular Vision, Molecular Vision, 2010, 16, pp.2612-25
Molecular Vision, 2010, 16, pp.2612-25
International audience; Purpose: Retinal degeneration has been associated with iron accumulation in age-related macular degeneration (AMD), and in several rodent models that had one or several iron regulating protein impairments. We investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::85c6d91e3e71861a523216a194cb5f29
https://serval.unil.ch/notice/serval:BIB_7C5D5BD8F500
https://serval.unil.ch/notice/serval:BIB_7C5D5BD8F500
Autor:
Rico Frigg, Wolfgang Raffelsberger, Christian Grimm, Andreas Wenzel, Marijana Samardzija, Markus Thiersch, Olivier Poch
Publikováno v:
BMC Genomics
BMC Genomics, BioMed Central, 2008, 9, pp.73. ⟨10.1186/1471-2164-9-73⟩
BMC Genomics, Vol 9, Iss 1, p 73 (2008)
BMC Genomics, BioMed Central, 2008, 9, pp.73. ⟨10.1186/1471-2164-9-73⟩
BMC Genomics, Vol 9, Iss 1, p 73 (2008)
Background Retinal degeneration is a main cause of blindness in humans. Neuroprotective therapies may be used to rescue retinal cells and preserve vision. Hypoxic preconditioning stabilizes the transcription factor HIF-1α in the retina and strongly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c19adfe9868c508aaa3b20910d36f33
https://www.zora.uzh.ch/id/eprint/3366/
https://www.zora.uzh.ch/id/eprint/3366/