Výsledky vyhledávání - "MESH : Radiation Chimera"

Homeostasis of Peripheral CD4+ T Cells: IL-2Rα and IL-2 Shape a Population of Regulatory Cells That Controls CD4+ T Cell Numbers

Autor: Martine Papiernik, Afonso R. M. Almeida, Antonio A. Freitas, Nicolas Legrand

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2002, 169 (9), pp.4850-60. ⟨10.4049/jimmunol.169.9.4850⟩
Journal of Immunology, 2002, 169 (9), pp.4850-60. ⟨10.4049/jimmunol.169.9.4850⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2002, 169 (9), pp.4850-60
Journal of immunology (Baltimore, Md., 169(9), 4850-4860. American Association of Immunologists

We show that the lymphoid hyperplasia observed in IL-2Rα- and IL-2-deficient mice is due to the lack of a population of regulatory cells essential for CD4 T cell homeostasis. In chimeras reconstituted with bone marrow cells from IL-2Rα-deficient do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5dd88a962005b9b0c7e534bc0c70aa
https://doi.org/10.4049/jimmunol.169.9.4850

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p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.: p16INK4a function in macrophages

Autor: Réjane Paumelle, Sébastien Fleury, Emmanuel Bouchaert, Jonathan Vanhoutte, Céline Cudejko, Giulia Chinetti-Gbaguidi, Bart Staels, Anne Tailleux, Sarah Anissa Hannou, Patrick Rémy, Lucía Fuentes, Kadiombo Bantubungi, Kristiaan Wouters, David Dombrowicz, Charlotte Paquet

Publikováno v: Blood
Blood, American Society of Hematology, 2011, 118 (9), pp.2556-66. ⟨10.1182/blood-2010-10-313106⟩
Blood, 118(9), 2556-66. The American Society of Hematology
Blood, 2011, 118 (9), pp.2556-66. ⟨10.1182/blood-2010-10-313106⟩

The CDKN2A locus, which contains the tumor suppressor gene p16INK4a, is associated with an increased risk of age-related inflammatory diseases, such as cardiovascular disease and type 2 diabetes, in which macrophages play a crucial role. Monocytes ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f26b1847c364ebe896c594cc036fad
https://doi.org/10.1182/blood-2010-10-313106

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A radiation hybrid map of the European sea bass (Dicentrarchus labrax) based on 1581 markers: Synteny analysis with model fish genomes

Autor: Christophe Hitte, Richard Guyon, Naoual Sadequi, Francis Galibert, Michaelle Rakotomanga, Filip Volckaert, Fabrice Senger

Publikováno v: Genomics
Genomics, Elsevier, 2010, 96 (4), pp.228-38. ⟨10.1016/j.ygeno.2010.07.007⟩
Genomics, 2010, 96 (4), pp.228-38. ⟨10.1016/j.ygeno.2010.07.007⟩

International audience; The selective breeding of fish for aquaculture purposes requires the understanding of the genetic basis of traits such as growth, behaviour, resistance to pathogens and sex determinism. Access to well-developed genomic resourc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ecdde96a96b1991954196c5a3528454

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Mucosal-associated invariant T cell–rich congenic mouse strain allows functional evaluation

Autor: Lionel Le Bourhis, Olivier Lantz, Yue Cui, Katarzyna Franciszkiewicz, Yvonne K. Mburu, Sylvie Rabot, Alexandra Kachaner, Emmanuel Martin, Claire Soudais, Stanislas Mondot, Virginie Premel, Livine Duban, Jean Jaubert, Molly A. Ingersoll, Jean-Pierre de Villartay

Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, 2015, 125 (11), pp.4171-4185. ⟨10.1172/JCI82424⟩
www.jci.org
Journal of Clinical Investigation, American Society for Clinical Investigation, 2015, 125 (11), pp.4171-4185. ⟨10.1172/JCI82424⟩
Journal of Clinical Investigation 11 (125), 4171-4185. (2015)

Mucosal-associated invariant T cells (MAITs) have potent antimicrobial activity and are abundant in humans (5%-10% in blood). Despite strong evolutionary conservation of the invariant TCR-alpha chain and restricting molecule MR1, this population is r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644f41ebbc4f1764869f11e52b9386a8
https://hal-pasteur.archives-ouvertes.fr/pasteur-01662502/file/JCI82424.pdf

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Stromal cell networks regulate thymocyte migration and dendritic cell behavior in the thymus

Autor: Jonathan A. Nowak, Marc Bajénoff, Mathieu Fallet, Stephanie L. Sanos

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2011, 186 (5), pp.2835-41. 〈10.4049/jimmunol.1003563〉
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2011, 186 (5), pp.2835-41. ⟨10.4049/jimmunol.1003563⟩
Journal of Immunology, 2011, 186 (5), pp.2835-41. ⟨10.4049/jimmunol.1003563⟩

After entry into thymus, T cell progenitors migrate in the cortex and the medulla while completing their education. Recent reports have documented the dynamic and tortuous behavior of thymocytes. However, other than chemokines and/or segregated thymi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb5aae61551b235c70ab6c348209c97
https://hal.archives-ouvertes.fr/hal-00609491

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Fibroblastic reticular cells guide T lymphocyte entry into and migration within the splenic T cell zone

Autor: Marc Bajénoff, Ronald N. Germain, Nicolas Glaichenhaus

Although a great deal is known about T cell entry into lymph nodes, much less is understood about how T lymphocytes access the splenic white pulp (WP). We show in this study that, as recently described for lymph nodes, fibroblastic reticular cells (F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9659527baa6a37bce8c5dbaa9bb9ba7b
https://hal.archives-ouvertes.fr/hal-00419277

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IFN-gamma mediates the rejection of haematopoietic stem cells in IFN-gammaR1-deficient hosts

Autor: Jean-François Emile, Guillaume Vogt, Laurent Rénia, Claire Soudais, Martin Rottman, Jean-Laurent Casanova, Hélène Decaluwe, Jean-Louis Gaillard

Publikováno v: PLoS Medicine
PLoS Medicine, Public Library of Science, 2008, 5 (1), pp.e26. ⟨10.1371/journal.pmed.0050026⟩
PLoS Medicine, Public Library of Science, 2008, 5 (1), pp.e26. 〈10.1371/journal.pmed.0050026〉
PLoS Medicine, Vol 5, Iss 1, p e26 (2008)
PLoS Medicine, 2008, 5 (1), pp.e26. ⟨10.1371/journal.pmed.0050026⟩

Background Interferon-γ receptor 1 (IFN-γR1) deficiency is a life-threatening inherited disorder, conferring predisposition to mycobacterial diseases. Haematopoietic stem cell transplantation (HSCT) is the only curative treatment available, but is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194b5ba86dbf8a305cc52296bc5a08fd
https://www.hal.inserm.fr/inserm-00700812/file/journal.pmed.0050026.pdf

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Cutting Edge: Independent Roles for IRF-3 and IRF-7 in Hematopoietic and Nonhematopoietic Cells during Host Response to Chikungunya Infection

Autor: Matthew L. Albert, Matthew R. Buckwalter, Michael S. Diamond, Olivier Schwartz, Melissa E. Laird, Clémentine Schilte

The host response to Chikungunya virus is dependent on the direct action of type I IFN on infected nonhematopoietic cells. Prior studies have demonstrated that multiple host sensors coordinate an antiviral response; however, the tissue source(s) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd355fa199660657f4633dcac80fed6a
https://hal-pasteur.archives-ouvertes.fr/pasteur-01372485

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p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages

Autor: Cudejko, Céline, Wouters, Kristiaan, Fuentes, Lucía, Hannou, Sarah Anissa, Paquet, Charlotte, Bantubungi, Kadiombo, Bouchaert, Emmanuel, Vanhoutte, Jonathan, Fleury, Sébastien, Remy, Patrick, Tailleux, Anne, Chinetti, Giulia, Dombrowicz, David, Staels, Bart, Paumelle, Réjane

Publikováno v: Blood
Blood, 2011, 118 (9), pp.2556-66. ⟨10.1182/blood-2010-10-313106⟩

International audience; The CDKN2A locus, which contains the tumor suppressor gene p16(INK4a), is associated with an increased risk of age-related inflammatory diseases, such as cardiovascular disease and type 2 diabetes, in which macrophages play a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::3c6eaa040bd9b7051f2a127e84c8ac0d
https://doi.org/10.1182/blood-2010-10-313106

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Expansion of peripheral naturally occurring T regulatory cells by Fms-like tyrosine kinase 3 ligand treatment

Autor: Nabil Bosco, Lee Kim Swee, Bernard Malissen, Antonius G. Rolink, Rhodri Ceredig

Publikováno v: Blood
Blood, American Society of Hematology, 2009, 113 (25), pp.6277-87. ⟨10.1182/blood-2008-06-161026⟩
Blood, 2009, 113 (25), pp.6277-87. ⟨10.1182/blood-2008-06-161026⟩

Fms-like tyrosine kinase 3 ligand (FLT3L) plays a major role in dendritic cell (DC) biology. Deficiency of FLT3L causes a dramatic decrease in DC numbers, whereas increasing its availability (by repetitive injections for 7-10 days) leads to a 10-fold

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f163bd1caa075f102658fe0b1e7ef8f
https://hal.archives-ouvertes.fr/hal-00407815

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