Zobrazeno 1 - 10 of 160 pro vyhledávání: '"MESH : RNA, Transfer"'
1
A structural inventory of native ribosomal ABCE1‐43S pre‐initiation complexes
Autor: Thomas Becker, Otto Berninghausen, Timur Mackens-Kiani, Roland Beckmann, Abdelkader Namane, Franz Herzog, Mia Potocnjak, Estelle Dacheux, Jingdong Cheng, Hanna Kratzat, Michael Ameismeier, Micheline Fromont-Racine
Publikováno v: EMBO Journal
EMBO Journal, EMBO Press, 2021, 40 (1), pp.e105179. ⟨10.15252/embj.2020105179⟩
EMBO Journal, 2021, 40 (1), pp.e105179. ⟨10.15252/embj.2020105179⟩
The EMBO Journal
In eukaryotic translation, termination and ribosome recycling phases are linked to subsequent initiation of a new round of translation by persistence of several factors at ribosomal sub‐complexes. These comprise/include the large eIF3 complex, eIF3
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9667dfae9df93ac8f5c6c681f4ddd1b
https://hal-pasteur.archives-ouvertes.fr/pasteur-03430600/document
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2
Somatic genetic rescue in Mendelian haematopoietic diseases
Autor: Alain Fischer, Patrick Revy, Caroline Kannengiesser
Publikováno v: Nature Reviews Genetics
Nature Reviews Genetics, Nature Publishing Group, 2019, 20 (10), pp.582-598. ⟨10.1038/s41576-019-0139-x⟩
International audience; Somatic mutations occur spontaneously in normal individuals and accumulate throughout life. These genetic modifications contribute to progressive ageing phenotypes and are directly involved in cancer development. However, a gr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e801e395a2a20dc34be1955e4c01cefa
https://hal.archives-ouvertes.fr/hal-02347753
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3
Defects in t6A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome
Autor: Arrondel, Christelle, Missoury, Sophia, Snoek, Rozemarijn, Patat, Julie, Menara, Giulia, Collinet, Bruno, Liger, Dominique, Durand, Dominique, Gribouval, Olivier, Boyer, Olivia, Buscara, Laurine, Martin, Gaëlle, Machuca, Eduardo, Nevo, Fabien, Lescop, Ewen, Braun, Daniela A., Boschat, Anne-Claire, Sanquer, Sylvia, Guerrera, Ida Chiara, Revy, Patrick, Parisot, Mélanie, Masson, Cécile, Boddaert, Nathalie, Charbit, Marina, Decramer, Stéphane, Novo, Robert, Macher, Marie-Alice, Ranchin, Bruno, Bacchetta, Justine, Laurent, Audrey, Collardeau-Frachon, Sophie, van Eerde, Albertien M., Hildebrandt, Friedhelm, Magen, Daniella, Antignac, Corinne, van Tilbeurgh, Herman, Mollet, Géraldine
Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.3967. ⟨10.1038/s41467-019-11951-x⟩
Nature Communications, 2019, 10 (1), pp.3967. ⟨10.1038/s41467-019-11951-x⟩
Nature Communications, 10(1). Nature Publishing Group
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
N6-threonyl-carbamoylation of adenosine 37 of ANN-type tRNAs (t6A) is a universal modification essential for translational accuracy and efficiency. The t6A pathway uses two sequentially acting enzymes, YRDC and OSGEP, the latter being a subunit of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e0b6268b745b3ed31edd2587f0bdbe99
https://www.hal.inserm.fr/inserm-02322309
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4
The structure of an E. coli tRNA f Met A 1-U 72 variant shows an unusual conformation of the A 1-U 72 base pair
Autor: Alexey Aleksandrov, Auriane Monestier, Pierre-Damien Coureux, Yves Mechulam, Emmanuelle Schmitt, Michel Panvert
Publikováno v: RNA
RNA, Cold Spring Harbor Laboratory Press, 2017, 23 (5), pp.673-682. ⟨10.1261/rna.057877.116⟩
Translation initiation in eukaryotes and archaea involves a methionylated initiator tRNA delivered to the ribosome in a ternary complex with e/aIF2 and GTP. Eukaryotic and archaeal initiator tRNAs contain a highly conserved A1–U72 base pair at the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc2c96f6476d95f0ed8cfac9e98107f
https://hal-polytechnique.archives-ouvertes.fr/hal-01961641/document
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5
Activation of a Unique Flavin-Dependent tRNA-Methylating Agent
Autor: Eduardo M. Bruch, Marc Fontecave, Martin J. Field, Sun Un, Djemel Hamdane
Publikováno v: Biochemistry
Biochemistry, American Chemical Society, 2013, 52 (49), pp.8949-8956. 〈10.1021/bi4013879〉
Biochemistry, American Chemical Society, 2013, 52 (49), pp.8949-8956. ⟨10.1021/bi4013879⟩
Biochemistry, 2013, 52 (49), pp.8949-8956. ⟨10.1021/bi4013879⟩
International audience; TrmFO is a tRNA methyltransferase that uses methylenetetrahydrofolate (CH2THF) and flavin adenine dinucleotide hydroquinone as cofactors. We have recently shown that TrmFO from Bacillus subtilis stabilizes a TrmFO-CH2-FADH add
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569c75d096d6fc0e4062c0c8b37545a7
https://doi.org/10.1021/bi4013879
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6
Trm112p Is a 15-kDa Zinc Finger Protein Essential for the Activity of Two tRNA and One Protein Methyltransferases in Yeast
Autor: Léon Dirick, Bruno Lapeyre, Glenn R. Björk, Marie-Hélène Mazauric, Suresh K. Purushothaman
Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2010, 285 (24), pp.18505-15. 〈10.1074/jbc.M110.113100〉
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2010, 285 (24), pp.18505-18515. ⟨10.1074/jbc.M110.113100⟩
International audience; The degenerate base at position 34 of the tRNA anticodon is the target of numerous modification enzymes. In Saccharomyces cerevisiae, five tRNAs exhibit a complex modification of uridine 34 (mcm(5)U(34) and mcm(5)s(2)U(34)), t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9a8ae0da66b4af63c96ac15c38a69a
https://doi.org/10.1074/jbc.m110.113100
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7
Small non coding RNAs in adipocyte biology and obesity
Autor: Ez-Zoubir Amri, Marcel Scheideler
Publikováno v: Mol. Cell. Endocrinol. 456, 87-94 (2017)
Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2017, 456, pp.87-94. ⟨10.1016/j.mce.2017.04.009⟩
International audience; Obesity has reached epidemic proportions world-wide and constitutes a substantial risk factor for hypertension, type 2 diabetes, cardiovascular diseases and certain cancers. So far, regulation of energy intake by dietary and p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6f74e6186ff653c58bd616ce3d8058
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=50937
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8
A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis
Autor: Carine Tisné, Yves Mechulam, Frédéric Dardel, Pierre Barraud, Emmanuelle Schmitt
Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2008, 36 (15), pp.4894-901. 〈10.1093/nar/gkn462〉
Nucleic Acids Research, Oxford University Press, 2008, 36 (15), pp.4894-901. ⟨10.1093/nar/gkn462⟩
International audience; In all organisms, translational initiation takes place on the small ribosomal subunit and two classes of methionine tRNA are present. The initiator is used exclusively for initiation of protein synthesis while the elongator is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641b980fef862354b4ffd7f474b225bf
https://doi.org/10.1093/nar/gkn462
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9
eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition
Autor: Adeline Renaud, A. Myasnikov, Lauriane Kuhn, Angelita Simonetti, Yaser Hashem, Jailson Brito Querido, Eder Mancera-Martínez
Publikováno v: Molecular Cell
Molecular Cell, 2016, 63 (2), pp.206-217. ⟨10.1016/j.molcel.2016.05.033⟩
Molecular Cell, Elsevier, 2016, 63 (2), pp.206-217. ⟨10.1016/j.molcel.2016.05.033⟩
International audience; mRNA translation initiation in eukaryotes requires the cooperation of a dozen eukaryotic initiation factors (eIFs) forming several complexes, which leads to mRNA attachment to the small ribosomal 40S subunit, mRNA scanning for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5b377195d9c0e3791d3c992cbf2e74
https://hal.science/hal-02294734
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10
In Vitro/In Vivo Production of tRNA for X-Ray Studies
Autor: Clément, Dégut, Alexandre, Monod, Franck, Brachet, Thibaut, Crépin, Carine, Tisné
Publikováno v: Methods in Molecular Biology
Methods in Molecular Biology, Humana Press/Springer Imprint, 2016, 1320, pp.37-57. ⟨10.1007/978-1-4939-2763-0_4⟩
Methods in Molecular Biology, 2016, 1320, pp.37-57. ⟨10.1007/978-1-4939-2763-0_4⟩
International audience; tRNAs occupy a central role in the cellular life, and they are involved in a broad range of biological processes that relies on their interaction with proteins and RNA. Crystallization and structure resolution of tRNA or/and t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3addea89076fcb43214c8f1ae35814a9
https://hal.univ-grenoble-alpes.fr/hal-01993848
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