Výsledky vyhledávání - "MESH : Proteoglycans"

Collagens and proteoglycans of the cornea: importance in transparency and visual disorders

Autor: François Malecaze, Stéphane Galiacy, Dawiyat Massoudi

Publikováno v: Cell and Tissue Research
Cell and Tissue Research, Springer Verlag, 2016, 363 (2), pp.337-349. ⟨10.1007/s00441-015-2233-5⟩

International audience; The cornea represents the external part of the eye and consists of an epithelium, a stroma and an endothelium. Due to its curvature and transparency this structure makes up approximately 70% of the total refractive power of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62260792949aba560b71ad7042d79632
https://doi.org/10.1007/s00441-015-2233-5

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Fisetin disposition and metabolism in mice: Identification of geraldol as an active metabolite. : Fisetin disposition and metabolism in mice

Autor: Daniel Scherman, Nicolas Auzeil, Yasmine Touil, François Boulinguez, Hanane Saighi, Anne Regazzetti, Guy G. Chabot

Publikováno v: Biochemical Pharmacology
Biochemical Pharmacology, Elsevier, 2011, 82 (11), pp.1731-9. ⟨10.1016/j.bcp.2011.07.097⟩
Biochemical Pharmacology, Elsevier, 2011, 82 (11), pp.1731-9. 〈10.1016/j.bcp.2011.07.097〉

International audience; Although the natural flavonoid fisetin (3,3',4',7-tetrahydroxyflavone) has been recently identified as an anticancer agent with antiangiogenic properties in mice, its in vivo pharmacokinetics and metabolism are presently not c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18137b514aee309e1bd8655e3f6a75c0
https://doi.org/10.1016/j.bcp.2011.07.097

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Asporin expression is highly regulated in human chondrocytes

Autor: Karim Boumediene, Nicolas Bigot, Elise Duval, Ikuyo Kou, Sylvain Leclercq, Philippe Galéra, Magalie Hervieu, Catherine Baugé

Publikováno v: Molecular Medicine
Molecular Medicine, Feinstein Institute for Medical Research, 2010, 17 (7-8), pp.816-23. ⟨10.2119/molmed.2011.00052⟩
Molecular Medicine, Feinstein Institute for Medical Research, 2010, 17 (7-8), pp.816-23. 〈10.2119/molmed.2011.00052〉

International audience; A significant association between a polymorphism in the D repeat of the gene encoding asporin and osteoarthritis, the most frequent of articular diseases, has been recently reported. The goal of the present study was to invest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67579252e0605e13bc06a938333d353e
http://arxiv.org/abs/1505.06921

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Sp1 Is Involved in Akt-mediated Induction of VEGF Expression through an HIF-1–independent Mechanism

Autor: Hui-Kuo G. Shu, Nabendu Pore, Gilles Pagès, Donald M. O'Rourke, Amit Maity, Bin Li, Eric J. Bernhard, Julie Milanini-Mongiat, Shuang Liu, David Stokoe, Daphne A. Haas-Kogan

Publikováno v: Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2004, 15 (11), pp.4841-53. ⟨10.1091/mbc.E04-05-0374⟩

International audience; Increased expression of vascular endothelial growth factor (VEGF) contributes to the growth of many tumors by increasing angiogenesis. Although hypoxia is a potent inducer of VEGF, we previously showed that epidermal growth fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9824e852e7562b5cef9cb17377794cd5
https://doi.org/10.1091/mbc.e04-05-0374

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Identification of SPOCK2 as a susceptibility gene for bronchopulmonary dysplasia

Autor: Pierre-Henri Jarreau, Emmanuelle Bouzigon, Johanna M. Huusko, Roberto Incitti, Ines Layouni, Jacques R. Bourbon, Richard Lenclen, Claude Danan, Florence Demenais, Mikko Hallman, Alice Hadchouel, Juliana Patkai, Christophe Delacourt, Xavier Durrmeyer, Marie-Laure Franco-Montoya

Publikováno v: American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2011, 184 (10), pp.1164-70. ⟨10.1164/rccm.201103-0548OC⟩
American Journal of Respiratory and Critical Care Medicine, 2011, 184 (10), pp.1164-70. ⟨10.1164/rccm.201103-0548OC⟩
American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2011, 184 (10), pp.1164-70. 〈10.1164/rccm.201103-0548OC〉

International audience; RATIONALE: Bronchopulmonary dysplasia is the most common chronic respiratory disease in premature infants. Genetic factors might contribute to bronchopulmonary dysplasia susceptibility. OBJECTIVES: To identify genetic variants

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85f2b310a0163bd5d2b5d8dbdb8e0d0
https://www.hal.inserm.fr/inserm-00617002/document

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Normal Human Keratinocytes Bind to the α3LG4/5 Domain of Unprocessed Laminin-5 through the Receptor Syndecan-1

Autor: Hugues Lortat-Jacob, Janine Bernaud, Uwe Odenthal, Sophie Bachy, Dominique Rigal, Patricia Rousselle, Neil Smyth, Osamu Okamoto

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2003, 278 (45), pp.44168-77. ⟨10.1074/jbc.M300726200⟩
Journal of Biological Chemistry, 2003, 278 (45), pp.44168-77. ⟨10.1074/jbc.M300726200⟩

Basal keratinocytes of the epidermis adhere to their underlying basement membrane through a specific interaction with laminin-5, which is composed by the association of alpha3, beta3, and gamma2 chains. Laminin-5 has the ability to induce either stab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2614ee3833026b2241fbd5ff78b338a2
https://doi.org/10.1074/jbc.m300726200

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Extracellular matrix-bound angiopoietin-like 4 inhibits endothelial cell adhesion, migration, and sprouting and alters actin cytoskeleton

Autor: Nicolas Bréchot, Ariane Galaup, Clémence Chomel, Laurent Muller, Marine Bignon, Stéphane Germain, Catherine Monnot, Pierre Corvol, Aurélie Cazes, Holger Weber, Sébastien Le Jan

Publikováno v: Circulation Research
Circulation Research, 2006, 99 (11), pp.1207-15. ⟨10.1161/01.RES.0000250758.63358.91⟩
Circulation Research, American Heart Association, 2006, 99 (11), pp.1207-15. ⟨10.1161/01.RES.0000250758.63358.91⟩
Circulation Research, American Heart Association, 2006, 99 (11), pp.1207-15. 〈10.1161/01.RES.0000250758.63358.91〉

Angiopoietin-like 4 (ANGPTL4) is a secreted protein that belongs to the angiopoietin family and is involved in angiogenesis and metabolism regulation. We previously reported the induction of angptl4 by hypoxia in endothelial cells and in human ischem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351b54b14556011dd324b5062af32194
https://www.hal.inserm.fr/inserm-00177171/document

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Nitric oxide (NO) and cartilage metabolism: NO effects are modulated by superoxide in response to IL-1

Autor: Jouzeau, Jean-Yves, Pacquelet, Sandrine, Boileau, Christelle, Nédélec, Emmanuelle, Presle, Nathalie, Netter, Patrick, Terlain, Bernard

Publikováno v: Biorheology
Biorheology, IOS Press, 2002, 39 (1-2), pp.201-14

International audience; Nitric oxide (NO) is thought to mediate most effects of interleukin-1 (IL-1) on cartilage. In vitro evidence includes the decreased synthesis of extracellular matrix components, the abnormal cell renewal, the decreased product

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6ac80c76fe9e3e5b075ff669ebd2723d
https://pubmed.ncbi.nlm.nih.gov/12082283

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