Expansion of nickel binding- and histidine-rich proteins during gastric adaptation of Helicobacter species

Autor: Frédéric Fischer, Egor Vorontsov, Evelyne Turlin, Christian Malosse, Camille Garcia, David L Tabb, Julia Chamot-Rooke, Riccardo Percudani, Daniel Vinella, Hilde De Reuse

Publikováno v: Metallomics
Metallomics, 2022, 14 (9), ⟨10.1093/mtomcs/mfac060⟩

Acquisition and homeostasis of essential metals during host colonization by bacterial pathogens rely on metal uptake, trafficking, and storage proteins. How these factors have evolved within bacterial pathogens is poorly defined. Urease, a nickel enz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e888eb250c3947d49343da350bc72553
https://hal.science/hal-03818858

True-atomic-resolution insights into the structure and functional role of linear chains and low-barrier hydrogen bonds in proteins

Autor: Valentin Borshchevskiy, Kirill Kovalev, Ekaterina Round, Rouslan Efremov, Roman Astashkin, Gleb Bourenkov, Dmitry Bratanov, Taras Balandin, Igor Chizhov, Christian Baeken, Ivan Gushchin, Alexander Kuzmin, Alexey Alekseev, Andrey Rogachev, Dieter Willbold, Martin Engelhard, Ernst Bamberg, Georg Büldt, Valentin Gordeliy

Publikováno v: Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2022, 29 (5), pp.440-450. ⟨10.1038/s41594-022-00762-2⟩

International audience; Hydrogen bonds are fundamental to the structure and function of biological macromolecules and have been explored in detail. The chains of hydrogen bonds (CHBs) and low-barrier hydrogen bonds (LBHBs) were proposed to play essen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db4299953238c5fbf7a1ff05e5a7bd9
https://pubmed.ncbi.nlm.nih.gov/35484235

Analysis of SEC-SAXS data via EFA deconvolution and Scatter

Autor: Tully, Mark, Tarbouriech, Nicolas, Rambo, Robert, Hutin, Stephanie

Publikováno v: Journal of visualized experiments : JoVE
Journal of visualized experiments : JoVE, 2021, 167, ⟨10.3791/61578⟩
Journal of visualized experiments : JoVE, JoVE, 2021, ⟨10.3791/61578⟩

International audience; BioSAXS is a popular technique used in molecular and structural biology to determine the solution structure, particle size and shape, surface-to-volume ratio and conformational changes of macromolecules and macromolecular comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bd5ca8424ccbc08477ed8c6f6a266798
https://hal.science/hal-03187951

Common homozygosity for predicted loss-of-function variants reveals both redundant and advantageous effects of dispensable human genes

Autor: Lluis Quintana-Murci, Antoine Favier, Franck Rapaport, David Neil Cooper, Peter D. Stenson, Etienne Patin, Laurent Abel, Jean-Laurent Casanova, Yufei Luo, Marie Lopez, Antonio Rausell, Yoann Seeleuthner

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, 117 (24), pp.13626-13636. ⟨10.1073/pnas.1917993117⟩
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (24), pp.13626-13636. ⟨10.1073/pnas.1917993117⟩

Humans homozygous or hemizygous for variants predicted to cause a loss of function of the corresponding protein do not necessarily present with overt clinical phenotypes. However, the set of effectively dispensable genes in the human genome has not y

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150e5a5a473272307710ff538827a274
https://hal.archives-ouvertes.fr/hal-03020429

Differentiation-dependent susceptibility of human muscle cells to Zika virus infection

Autor: Gillian Butler-Browne, Jim Zoladek, Ingo Riederer, Quentin Giai Gianetto, Philippe Roingeard, Patricia Jeannin, Julien Burlaud-Gaillard, Pierre-Emmanuel Ceccaldi, Mariette Matondo, Valérie Choumet, Thibault Chaze, Vincent Legros, Vincent Mouly, Philippe V. Afonso, Antoine Gessain, Mariela-Natacha Gonzàlez

Publikováno v: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2020, 14 (8), pp.e0008282. ⟨10.1371/journal.pntd.0008282⟩
PLoS Neglected Tropical Diseases, 2020, 14 (8), pp.e0008282. ⟨10.1371/journal.pntd.0008282⟩
PLoS Neglected Tropical Diseases, Vol 14, Iss 8, p e0008282 (2020)
PLoS Neglected Tropical Diseases, Public Library of Science, 2020, 14, ⟨10.1371/journal.pntd.0008282⟩

Muscle cells are potential targets of many arboviruses, such as Ross River, Dengue, Sindbis, and chikungunya viruses, that may be involved in the physiopathological course of the infection. During the recent outbreak of Zika virus (ZIKV), myalgia was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae776d91cb415f518bbec3e604af2555
https://hal.sorbonne-universite.fr/hal-02939106/file/journal.pntd.0008282.pdf